Xem 1-20 trên 20 kết quả Epigenetic effects
  • We all know only too well that our way of life, the food we eat, smoking, stress or environmental toxins infl uence our health. But we have just started to learn how these environmental factors cooperate with our hereditary genetic dispositions to determine health or the development of diseases. Moreover, we did not know until recently that all these factors may also infl uence the health of our children and grandchildren to whom we may transmit functional changes of our genes.

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  • The impact of biomarkers in present day health care system, health management and healthy life is enormous. Clinicians need them for diagnosis, prognosis, effect of therapeutic intervention, and most importantly, for early detection of a disease. Pharmaceutical industries need them for new drug discovery and drug efficiency test. Regulatory authorities need them for testing toxicity and environmental impact. Epidemiologists need them for population screening and risk factor determination.

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  • Most certainly, Latinas are facing a serious health care crisis that threatens to undermine the reproductive health and overall well-being of themselves, their families and their communities. Despite the growing number of uninsured Latinas and the significant health disparities they face, health policy makers have paid little attention to the reproductive health needs of Latinas. Against this backdrop, we are also witnessing an onslaught of attacks on the reproductive freedom of women in this country that will no doubt disproportionately impact Latinas.

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  • In the wake of the 20-year anniversary of Earth Day in 1990 and the Gulf War shortly thereafter, environmental issues and renewable energy enjoyed renewed interest. Several states enacted new tax credits and began new loan and grant programs. In the late 1990s, states continued to take the lead in developing programs, policies, and incentives to promote the use of renewable energy, in part as a result of electric utility restructuring.

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  • Modern office chair design has solved many of the problems of fitting a wide range of different sized people by providing convenient adjustments. The ranges of adjustments should be checked to ensure that they cater as much as possible for the ethnic mix in the workforce involved. For example, to ensure that all people can obtain good back support, the backrest must be sufficiently adjustable in the fore and aft direction. This changes the effective depth of the seat which should be no greater than the buttock to popliteal length. The backrest height should also be...

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  • If one posits a powerful connection among learning, doing and understanding, then the argument for teaching media literacy is a compelling one. And equally, there is a compelling case to be made that the teaching of media literacy should be global – the content of the course should be global, because the effects of media messages certainly are. There is no global issue or political arena in which the statement of problems and the framing of possible solutions are not influenced by media coverage.

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  • Bacillus Thuringiensis (Bt): A pest control product that is made from beneficial bacteria and applied as a spray to kill caterpillars. Sold under a variety of names such as Thuricide, Dipel, and Bio-Worm and others. Use Bacillus thuringiensis ëIsraelensisí (Bti) in water for the control of mosquito larvae and for control of fungus gnats in pot plants in office buildings. Use Garrett Juice with Bt for extra effect. Molasses also helps. It provides protein and keeps insect-killing bacteria alive on the foliage longer ñ even during rain.

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  • Physical damage functions relating health (mortality and morbidity) to air pollution levels have been estimated over a number of years in different countries. Although the net effect of pollutants on health is unclear, the Committee of the Medical Effects of Air Pollution (COMEAP), set up by the UK government has found the strongest link between health and pollution to be for particulates (PM10), sulphur dioxide (SO2) and ozone (O3) (Department of Health, 1998).

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  • The Internet’s rapid and profound entry into our lives quite understandably makes people wonder how, both individually and collectively, we have been affected by it. When major shifts in technology use occur, utopian and dystopian views of their impact on society often abound, reflecting their disruptiveness and people’s concerns. Given its complex uses, the Internet, both as a technology and as an environment, has had both beneficial and deleterious effects. Above all, though, it has had transformative effects.

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  • The Seventh Directive complements these harmonization efforts with requirements on when and how firms must prepare consolidated financial accounts. Both directives effectively prescribe a common set of accounting rules for both consolidated and unconsolidated (or parent-only) financial statements. The directives had to be transformed into national laws by the member states during the late 1980s and early 1990s. As a result, accounting standards across EU member states are fairly similar, though not necessarily equal in every respect.

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  • Carbon Monoxide is toxic to humans. Even healthy people can be affected by carbon monoxide. People who breathe high levels of CO can develop vision problems, redued ability to work or learn, or have difficulty performing complex tasks. People who have heart disease may cause chest pains or other more serious cardiovascular effects. The problem with air pollution is that it looks to be increasing in toxicity rather than being solved or reduced. More and more people are driving automobiles or trucks. And the Earth’s growing population is requiring more electricity to...

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  • Therefore an Executive MBA degree program was created that is open for management / business ad- ministration graduates as well as for graduates from other disciplines (e.g. computer science, engineer- ing, economics, and psychology). The Executive MBA in Business Engineering program is offered as a part-time program. To guarantee an effective learning situation, two-week learning periods at the uni- versity alternate with six-week practice periods in which the students return to their jobs.

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  • The total investment required for the six corridors is Rp. 4,012 trillion. From this, it is expected that the Sumatra Corridor will receive Rp. 714 trillion (18% of total investment), Rp. 945 (24% of total investment) for the Kalimantan corridor, Rp. 1,290 trillion (32% of total investment) for the Java corridor, Rp. 309 trillion (8% of total investment) for the Sulawesi Corridor, Rp. 133 trillion (3% of total investment) for the BaliNusa Tenggara Corridor and lastly Rp. 622 trillion (15% of total investment) for the Papua Kepulauan Maluku Corridor. See figure below. ...

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  • This book emerges from two separate, but intersecting, strands of work that began in the late 1980s, when the World Bank ini- tiated a review of priorities for the control of specific diseases. The review generated findings about the comparative cost- effectiveness of interventions for most diseases important in developing countries. The purpose of the cost-effectiveness analysis (CEA) was to inform decision making within the health sectors of highly resource-constrained countries.

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  • Chapter 16 - Gene regulation in eukaryotes. The main contents of this chapter include all of the following: Overview of eukaryotic gene regulation, control of transcription initiation, chromatin structure and epigenetic effects, regulation after transcription, a comprehensive example: sex determination in Drosophila.

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  • Hydroxyurea was fi rst used as a treatment for cancer. It is a powerful medicine. But hydroxyurea is given at a much lower dose to children with sickle cell disease. No serious side effects have been seen in children with sickle cell disease. The dose used in the treatment of sickle cell disease does not cause the usual side effects seen with cancer treatment. It does not cause hair loss, vomiting, weakness, or loss of appetite. Many children with sickle cell disease have taken hydroxyurea for several years without problems. Hydroxyurea is very safe when given by medical specialists...

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  • It will help to connect with local training programs, provide internships, and offer professional development. Some health centers may be able to have trained community health workers perform these functions but the community health worker should be supervised by an MSW level social worker or by a registered nurse. Language access and delivery of culturally appropriate services are also essential components of providing quality care.

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  • Various factors are associated with an increased risk of becoming infected and subsequently developing disease (Table 1 and Fig. 1). Transmission is most efficient in poorly ventilated, crowded environments. Droplets become diluted once they enter the external environment and M. tuberculosis is rapidly destroyed by ultraviolet radiation. Following lung infection, multiplication and dissemination of the organism is contained once cell-mediated immunity develops at 2–12 weeks.

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  • International agreements, supported by hard science, are proving effective in combating wide-ranging environmental threats such as ozone depletion and long-range transboundary air pollution. Can similar agreements be implemented to address the more complex risks posed by global climate change? Scientific analysis in general, and the health sector in particular, need to inform and help advance ongoing policy discussions.

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  • Mixed lineage leukemias (MLLs) are histone-methylating enzymes with critical roles in gene expression, epigenetics and cancer. Although MLLs are important gene regulators little is known about their own regulation. Herein, to understand the effects of toxic stress onMLLgene regulation, we treated human cells with a common food contaminant mycotoxin, deoxynivalenol (DON).

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