Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: The role of a pseudocapsula in thymic epithelial tumors: outcome and correlation with established prognostic parameters. Results of a 20-year single centre retrospective analysis...
(BQ) Part 2 book "Liver pathology" presentation of content: Liver allograft pathology, liver involvement in other systemic diseases, benign epithelial nodules and tumors, malignant epithelial tumors, vascular tumors, tumors with mesenchymal component.
Expression of the tumor suppressor p16
after stable transfection can
restore the susceptibility of epithelial tumor cells to anoikis. This property
is linked to increases in the expression and cell-surface presence of the
fibronectin receptor. Considering its glycan chains as pivotal signals, we
assumed an effect of p16
Cancer may constitute the most extensively studied
disease entity of our time. Nevertheless, our comprehension
of the cellular and molecular pathology
of malignant transformation is incomplete. In view
of the diverse clinical presentations of various
malignancies, doubts may be raised as to whether it
is appropriate to refer to cancer as one group of disease
states. The notion of malignant tumors as a
pathologic and pathophysiologic class of conditions
begs the question for defining criteria that characterize
all malignant growths, regardless of their tissue
Accurate statistics on cancer occurrence and outcome are essential both for the purposes of
research and for planning and evaluation programmes for cancer control (Parkin, 2006).
Although tumours of thyroid account for only 1% of the overall human cancer burden, they
represent the most common malignancies of the endocrine system and pose a significant
challenge to pathologists, surgeons and endocrinologists. Among epithelial tumors,
carcinomas of follicular cell origin far outnumber those of C-cell origin.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells...
Coordinated expression and upregulation of interleukin-1a, interleukin-1b,
tumor necrosis factor-a, interleukin-6, granulocyte–macrophage colony-stimulating factor, interleukin-8, monocyte chemotactic protein-1 (MCP-1)
and epithelial cell derived neutrophil activator-78, with chemoattractant
and proinflammatory properties of various cytokine families, were obtained
in the intestinal epithelial cell line Int407 upon Vibrio choleraeinfection.
The eye lens is composed of fiber cells that differentiate from epithelial cells
on its anterior surface. In concert with this differentiation, a set of proteins
essential for lens function is synthesized, and the cellular organelles are
degraded. DNase II-like acid DNase, also called DNase IIb, is specifically
expressed in the lens, and degrades the DNA in the lens fiber cells.
The interaction of the antibacterial phosphonodipeptide
/peptide cotransporters was
studied in Caco-2 cells, expressing the low-affinity intestinal
type peptide transporter 1 (PEPT1), and SKPT cells,
expressing the high-affinity renal type peptide transporter 2
(PEPT2). Alafosfalin strongly inhibited the uptake of
C]glycylsarcosine withKi values of 0.19 ± 0.01 mMand
0.07 ± 0.01 mMfor PEPT1 and PEPT2, respectively.
A novel hypoxically regulated intercellular junction protein
(claudin-like protein of 24 kDa, CLP24) hasbeen identified
that shows homology to the myelin protein 22/epithelial
membrane protein 1/claudin family of cell junction proteins,
which are involved in the modulation of paracellular per-meability. The CLP24 protein containsfour predicted
transmembrane domains and a C-terminal protein–protein
The retinal pigment epithelium (RPE) is essential for main-tenance of photoreceptors and normally functions under
conditions enriched with reactive oxygen species. RPE
therefore expresses various defense enzymes against oxida-tive stress, including heme oxygenase-1 (HO-1). HO-1
catalyzes heme breakdown to release iron, carbon monox-ide, and biliverdin, which is reduced to bilirubin, a potent
radical scavenger. HO-1 expression is induced by various
environmental factors, which has been established as a def-ense mechanism....
Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Malignant phyllodes tumor with heterologous liposarcomatous differentiation and tubular adenoma-like epithelial component...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome...
For decades, endocytosis has been recognized as a fundamental cellular process that
regulates the uptake of small molecules (cell surface proteins, bacteria, toxins, etc.) into
the cell. So why, after years of study, does this simple process warrant more
discussion? Anyone who has examined the endocytic pathway will appreciate that this
conceptually simple mechanism is highly complex and sophisticated. Like ballet
dancers who make their synchronous performance seem effortless, the cell brings in
molecules via a carefully choreographed mechanism.
The CCAAT-Displacement-Protein (CUX1) can transcriptionally repress
sucrase–isomaltase gene expression, a specific product of enterocytes that
becomes re-expressed during human colonic polyposis. Little is known of
the gene repertoire that is directly affected by CUX1 in the intestinal
Lactoferrin (LF) is a Fe
-binding glycoprotein, first
recognized in milk and then in other human epithelial
secretions and barrier fluids. Many different functions have
been attributed to LF, including protection from iron-induced lipid peroxidation, immunomodulation and cell
growthregulation, DNA binding, and transcriptional acti-vation. Its physiological role is still unclear, but it has been
suggested to be responsible for primary defense against
microbial and viral infection.
The heat-stable enterotoxin peptides (ST) produced by
enterotoxigenicEscherichia coliare one of the major causes
of transitory diarrhea in the developing world. Toxin bind-ing to its receptor, guanylyl cyclase C (GC-C), results in
receptor activation and the production of high intracellular
levels of cGMP. GC-C is expressed in two differentially
glycosylated forms in intestinal epithelial cells. Prolonged
exposure of human colonic cell lines to ST peptides induces
cellular refractoriness to the ST peptide, in terms of intra-cellular cGMP accumulation....
(BQ) Part 2 book "Gastrointestinal pathology and its clinical implications" presents the following contents: Gastric epithelial polyps and tumors, small and large bowel structure - Developmental and mechanical disorders, small bowel mucosal disease, small bowel mucosal disease, enteric infections and associated diseases, small and large bowel polyps and tumors, the anal canal.
(BQ) Part 2 book "Dermatology acne" presentation of content: The Vasculopathic pattern, panniculitis, fibrosing dermatitis, the depositional pattern, the melanocytic tumors, epithelial neoplasms, adnexal neoplasms, the mesenchymal tumors.
(BQ) Part 1 book "Pathology of the maxillofacial bones - A guide to diagnosis" presentation of content: Non-neoplastic diseases, cysts, epithelial odontogenic tumors, odontogenic tumors mesenchymal, odontogenic tumors - mixed epithelial and mesenchymal, odontogenic tumors - malignant.