Xem 1-20 trên 1414 kết quả Failure
  • The purpose of this book is to look at a wide variety of these brand failures, and brands which have so far managed to narrowly escape death, in order to explore the various ways in which companies can get it wrong. The process of branding was. The process of branding was developed to protect products from failure. This is easy to see if we trace this process back to its 19th-century origins. In the 1880s, companies such as Campbell’s, Heinz and Quaker Oats were growing ever more...

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  • Twenty years ago in the twenty-first edition of the Principles and Practice of Medicine, the authors described what was then the practice for the pharmacologic therapy of patients with heart failure, which included digoxin and a diuretic [1]. In addition, the authors noted that recent studies had supported the potential use of vasodilators in the treatment of this population of patients.

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  • Your kidneys filter wastes from your blood and regulate other functions of your body. When your kidneys fail, you need treatment to replace the work of healthy kidneys to survive. Developing kidney failure means that you have some decisions to make about your treatment. If you choose to receive treatment, your choices are hemodialysis, peritoneal dialysis, and kidney transplantation. Each of them has advantages and disadvantages. You may also choose to forgo treatment.

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  • The purpose of this book is to look at a wide variety of these brand failures, and brands which have so far managed to narrowly escape death, in order to explore the various ways in which companies can get it wrong. The process of branding was. The process of branding was developed to protect products from failure. This is easy to see if we trace this process back to its 19th-century origins. In the 1880s, companies such as Campbell’s, Heinz and Quaker Oats were growing ever more...

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  • Preventing System Failures Now it is time to discuss the measures that will help you prevent system failures. Naturally, all emergency planning should be done beforehand.

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  • Dealing with Update Failures So far, the examples you've seen have assumed that the updates pushed to the database by the Update() have succeeded.

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  • Epidemiology Idiopathic MDS is a disease of the elderly; the mean age at onset is 68 years. There is a slight male preponderance. MDS is a relatively common form of bone marrow failure, with reported incidence rates of 35 to 100 per million persons in the general population and 120 to 500 per million in the elderly. MDS is rare in children, but monocytic leukemia can be seen. Therapy-related MDS is not age-related and may occur in as many as 15% of patients within a decade following intensive combined modality treatment for cancer. Rates of MDS have increased over time,...

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  • Pathophysiology Bone marrow failure results from severe damage to the hematopoietic cell compartment. In aplastic anemia, replacement of the bone marrow by fat is apparent in the morphology of the biopsy specimen (Fig. 102-1) and MRI of the spine. Cells bearing the CD34 antigen, a marker of early hematopoietic cells, are greatly diminished, and in functional studies, committed and primitive progenitor cells are virtually absent; in vitro assays have suggested that the stem cell pool is reduced to ≤1% of normal in severe disease at the time of presentation. Figure 102-1 A.

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  • Bài giảng “Managing chronic heart failure patient in chronic kidney disease” trình bày các nội dung: Epidemiology, pathophysiolog, management, modification of risk factors, angiotensin-converting enzyme inhibitors,… Mời các bạn cùng tham khảo nội dung chi tiết.

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  • Harrison's Internal Medicine Chapter 102. Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes Aplastic Anemia, Myelodysplasia, and Related Bone Marrow Failure Syndromes: Introduction The hypoproliferative anemias are normochromic, normocytic or macrocytic and are characterized by a low reticulocyte count. Deficient production of RBCs occurs with marrow damage and dysfunction, which may be secondary to infection, inflammation, and cancer.

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  • Aplastic Anemia Definition Aplastic anemia is pancytopenia with bone marrow hypocellularity. Acquired aplastic anemia is distinguished from iatrogenic marrow aplasia, marrow hypocellularity after intensive cytotoxic chemotherapy for cancer. Aplastic anemia can also be constitutional: the genetic diseases Fanconi's anemia and dyskeratosis congenita, while frequently associated with typical physical anomalies and the development of pancytopenia early in life, can also present as marrow failure in normal-appearing adults.

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  • Infections Hepatitis is the most common preceding infection, and posthepatitis marrow failure accounts for about 5% of etiologies in most series. Patients are usually young men who have recovered from a bout of liver inflammation 1 to 2 months earlier; the subsequent pancytopenia is very severe. The hepatitis is seronegative (non-A, non-B, non-C, non-G) and possibly due to a novel, as yet undiscovered, virus. Fulminant liver failure in childhood also follows seronegative hepatitis, and marrow failure occurs at a high rate in these patients.

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  • Immune-Mediated Injury The recovery of marrow function in some patients prepared for bone marrow transplantation with antilymphocyte globulin (ALG) first suggested that aplastic anemia might be immune-mediated. Consistent with this hypothesis was the frequent failure of simple bone marrow transplantation from a syngeneic twin, without conditioning cytotoxic chemotherapy, which also argued both against simple stem cell absence as the cause and for the presence of a host factor producing marrow failure. Laboratory data support an important role for the immune system in aplastic anemia.

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  • Definition and Differential Diagnosis PRCA is characterized by anemia, reticulocytopenia, and absent or rare erythroid precursor cells in the bone marrow. The classification of PRCA is shown in Table 102-4. In adults, PRCA is acquired. An identical syndrome can occur constitutionally: Diamond-Blackfan anemia, or congenital PRCA, is diagnosed at birth or in early childhood and often responds to glucocorticoid treatment; a minority of patients have etiologic mutations in a ribosomal RNA processing gene called RPS19.

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  • The risk of sudden death from cardiac causes is increased among survivors of acute myocardial infarction with reduced left ventricular systolic function. We assessed the risk and time course of sudden death in high-risk patients after myocardial infarction. methods We studied 14,609 patients with left ventricular dysfunction, heart failure, or both after myocardial infarction to assess the incidence and timing of sudden unexpected death or cardiac arrest with resuscitation in relation to the left ventricular ejection fraction....

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  • Struggle, failure, triumph: while triumph is the thing sought, struggle has its joy, and failure is not without its uses. "It is not the goal," says Jean Paul, "but the course which makes us happy." The law of life is what a great orator affirmed of oratory--"Action, action, action!" As soon as one point is gained, another, and another presents itself. "It is a mistake," says Samuel Smiles, "to suppose that men succeed through success; they much oftener succeed through failure.

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  • (BQ) Part 1 book "Heart failure management the neural pathways" presents the following contents: Therapies in heart failure, tomorrow may be too lat, atrial fibrillation, heart failure, and the autonomic nervous system, cardiovascular serenade - listening to the heart, cerebral aging - implications for the heart autonomic nervous system regulation,...

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  • Heart failure is a pathological state in which cardiac output is insufficient to meet the body's demand for oxygen present in every living situation of the patient. Invite you to read the Sermon heart failure reference to learn more about heart failure classification, cause heart failure, heart failure symptoms, ...

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  • Competitive markets usually do a remarkably effective job of allocating society’s scarce resources to their most highly valued uses. Thus, we begin this chapter by demonstrating how properly functioning markets efficiently allocate resources. We then explore what happens when markets don’t function properly. In some circumstances, economically desirable goods are not produced at all. In other situations, they are either overproduced or underproduced. This chapter focuses on these situations, which economists refer to as market failures.

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  • Research objectives: Describe the prevalence, clinical and para-clinical features of deep vein thrombosis at lower extremities using venous Doppler ultrasound. Identify the risk factors of deep vein thrombosis at lower extremities and its correlation to heart failure severity.

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