Fatty acids (FAs) can be degraded via different mechanisms including
a-, b- and x-oxidation. In humans, a range of different genetic diseases has
been identified in which either mitochondrial FAb-oxidation, peroxisomal
FAb-oxidation or FAa-oxidation is impaired. Treatment options for most
of these disorders are limited.
In plants, fatty acids (FA) are subjected to various types of oxygenation
reactions. Products include hydroxyacids, as well as hydroperoxides, epox-ides, aldehydes, ketones and a,x-diacids. Many of these reactions are cata-lysed by cytochrome P450s (P450s), which represent one of the largest
superfamilies of proteins in plants.
In this chapter 16 (part 3), you will: Know the reactions/enzymes/co-substrates/intermediates of fatty acid synthesis, be able to recognize the intermediates of one round of fatty acid synthesis, know the co-enzymes and co-substrates involved in each step, know how the fatty acid synthetic machinery is organized in plants, bacteria and animals.
The aims of this paper were to investigate the component fatty acids of some freshwater fish
species by comparing the levels of essential fatty acids present. The FAME were determined
by GC-MS and were identified using retention time locked methods and retention time
databases. The fatty acids profiles include minor amounts of odd-number, branched-chain,
and even-number fatty acids as well as saturated components, the MUFA and PUFA. The
major SFA were C14:0 and C16:0. The C18:1 was the prominent MUFA....
Fatty acid synthase (FAS) is uniquely expressed at high levels in cancer
cells and adipose tissue. The objectives of this study were to identify, purify
and validate soy FAS inhibitory peptides and to predict their binding
modes. Soy peptides were isolated from hydrolysates of purifiedb-conglyci-nin by co-immunoprecipitation and identified using LC-MS⁄MS.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:
Dietary intake of fish, omega-3, omega-6 polyunsaturated fatty acids and vitamin D and the prevalence of psychotic-like symptoms in a cohort of 33 000 women from the general population
Fatty acids are an important energy source, for they yield over twice as much energy as an equal mass of carbohydrate or protein. In humans, the primary dietary source of fatty acids is triacylglycerols. This lecture will describe the metabolism of fatty acids. The two main components of fatty acid metabolism are β oxidation and fatty acid synthesis. Upon completion of this lecture, you will understand that the fatty-acid breakdown reactions of β oxidation result in the formation of reduced cofactors and acetyl-CoA molecules, which can be further catabolized to release free energy.
three groups of 40 perch breeders were reared in order to study the effects of 3 different levels of dietary n-3 and n-6 fatty acids on egg quality. two experimental diets, r1 and r2 (n-3/n-6 = 0.13 and 35.54, respectively), were compared to one commercial food, r3 (n-3/n-6 = 3.48). spawning and fertilization rates were high for diets r1 and r3, which displayed a n-3/n-6 ratio of 0.77 and 2.34 in the eggs, respectively, by comparison with r2 (n-3/n-6 = 4.87), which produced low reproductive performances. We can conclude that dietary n-3 and n-6 FA levels influence egg and larval...
Interest in food lipids has grown dramatically in recent years as a result of findings related to their
health effects. Fats and oils have often been condemned because of their high energy value and due
to potential health problems associated with certain saturated fatty acids as well as trans fats.
However, lipids are important in that they provide essential fatty acids and fat-soluble vitamins as
well as flavor, texture, and mouthfeel to foods.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Attenuating posttraumatic distress with omega-3 polyunsaturated fatty acids among disaster medical assistance team members after the Great East Japan Earthquake: The APOP randomized controlled trial
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: SuperSAGE analysis of the Nicotiana attenuata transcriptome after fatty acid-amino acid elicitation (FAC): identification of early mediators of insect responses
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Preparation of Monodisperse Iron Oxide Nanoparticles via the Synthesis and Decomposition of Iron Fatty Acid Complexes
In the present study, acyl-CoA synthetase mutants of Saccharomyces
cerevisiae were employed to investigate the impact of this activity on cer-tain pools of fatty acids. We identified a genotype responsible for the secre-tion of free fatty acids into the culture medium.
Glycosphingolipids are located in cell membranes and the brain is especi-ally enriched. We speculated that the subcellular location of glycosphingo-lipids depends on their fatty acid chain length because their sugar residues
are constant, whereas fatty acid chain length can vary within the same
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài:Dietary fatty acid intake affects the risk of developing bone marrow lesions in healthy middle-aged adults without clinical knee osteoarthritis: a prospective cohort study...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Dietary n-3 fatty acids have suppressive effects on mucin upregulation in mice infected with Pseudomonas aeruginosa...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity