Tremendous strides have been made in the field of antiaging
medicine since the publication of my first book, The
Wrinkle Cure, in 2000. It was there that I first introduced my
inflammation–aging theory, which firmly places chronic,
low-grade invisible inflammation at the center of aging, age-related
diseases, and a host of degenerative conditions.
This theory was often dismissed with either ridicule or skepticism—
however, science has now recognized its validity, and inflammation has
been overwhelmingly recognized as a serious threat to health and
Rural residents have higher rates of age-adjusted mortality, disability, and chronic disease than their urban counterparts. Contributing negatively to the health status of rural residents are their lower socioeconomic status, higher incidence of both smoking and obesity, and lower levels of physical activity. Contributing negatively to the health status of farmers are the high risks from workplace hazards; contributing positively are farmers¿ higher socioeconomic status, lower incidence of smoking, and more active lifestyle.
Theory argues that R&D intensity and acquisition activity may be either directly or inversely related. However, empirically we know relatively little about which firms are responsible for acquisition activity in high-technology industries.
This book developed from my teaching and consulting experiences
going back three decades. Working with Fortune 500
clients, I have been constantly amazed that finance is almost an
afterthought in the everyday world of business—except, of
course, for such financial services companies as banks and securities
CASE 1: Pizza Hut CASE 2: General Motors Corporation Introduction The Value Chain Primary Activities Support Activities Pizza Industry Value Chain Primary Activities Support Activities Automobile Industry Value Chain Primary Activities Support Activities The Value Chain as Part of a Business System Pizza Hut General Motors Capability Drivers First-Mover Status Scale of Operation Experience Interrelationships Assessing Competitive Advantage First-Mover Advantages Scale and Experience Advantages The Growth of the Internet and Competitive Advantage Diagnosing Pizza Hut’s Capabilities First-...
Explain the internal context of strategy. Identify a firm’s resources and capabilities and explain
their role in its performance. Define dynamic capabilities and explain their role in both
strategic change and a firm’s performance. Explain how value‑chain activities are related to firm
performance and competitive advantage. Explain the role of managers with respect to resources,
capabilities, and value‑chain activities.
Three options emerged for harmonising the scope of institutions that are deemed to provide
sufficient guarantees in terms of prudential regulation and capital requirements to fulfil the
task of being a depositary. The impact assessment concludes that both credit institutions and
regulated investment firms provide sufficient guarantees in terms of prudential regulation,
capital requirements and effective supervision to act as UCITS depositaries. Other institutions
(such as, e.g.
Writing is the most dreaded activity for my fourth grade students. Not only do
they strongly oppose writing in all forms, they struggle to use the proper mechanics to
communicate effectively with a targeted audience. My frustration with my students’
abilities to be effective writers led me to investigate the following question: “Will the
implementation of selected lessons and activities taken from 6+1 Traits of Writing and
Writer’s Workshop equip my students with the descriptive and mechanical writing skills
they need to become proficient writers?” ...
This book developed as a result of my requirement to have a simple, comprehensive
and well-structured repertoire of tools for my own consulting activities. Whenever I
wanted to ‘pull the rabbit out of the hat’, I used to waste time browsing through previous
project work to find things I had done previously. In order to avoid having to
‘reinvent the wheel’ each time, I developed my own ‘cheat sheet’ – a list with names
of tools to prompt and remind me of what was ‘available’....
Once the law goes into effect, individuals who do not
have minimal essential coverage will be required to
pay a tax penalty. e penalty will be waived if the cost
of coverage exceeds 8 percent of family income, if an
individual is uninsured for fewer than three months, if
an individual’s income is below the federal tax-filing
threshold, or if the individual meets other criteria for
exemption described in the ACA. New employerresponsibility
provisions will apply to firms with 50 or
more full-time equivalent employees.
Gaps in current knowledge
To strengthen current knowledge, particularly on effectiveness,
cost/benefit analysis and the impact on health of WHP programmes,
further research is needed. The development of simple and easy-to-use
validated instruments for diet and physical activity evaluation is
Are these practices making a difference? According
to survey respondents, organizational project
management maturity is improving (Figure 2). Twenty
percent describe their organizations as having “high”
overall project management maturity, up from 11%
in 2006. Perhaps not surprisingly, larger firms tend
to report higher maturity levels. Nearly 30% of
firms with at least US$1 billion in annual revenues
report a high maturity level compared to just 10%
of those with annual revenues under US$50 million.
The automotive industry in India was heavily regulated until the 1970s. The automotive firms
were obliged to obtain licenses from the Indian government for various firm activities. The
1980s witnessed some relaxation in the regulations and the entry of Japanese firms. In the
early 1990s, India undertook historic economic reforms under which the automotive industry
was liberalised. Various government interventions in the form of policies, existing at various
points of time, have influenced the development of India’s automotive industry over these
Individuals are then identified as workers and nonworkers
(i.e., the unemployed and the respective dependents/
spouses of workers). Workers are assigned
employer wage distribution characteristics from EDD
2007 data based on firm size and insurance offer status
from their MEPS record. e firms are then statistically
matched to the Employer Sponsored Insurance (ESI)
data from the 2010 CEHBS, which contains additional
information on the actuarial value of the health plans
Co-operative movement in Tripura started in 1949 and over the years there has been a
gradual expansion in size, numbers and volume of operations of Co-operative Societies in
the State. Now Co-operative Societies of diversified activities have come up and with the
growth of the Co-operative movement its accounting system also gets complicated. Audit of
Co-operatives has become a big job to complete it in time maintaining the quality and
In brief, this dissertation presents four major contributions: (1) Regulatory actors affect strat-
egy formation. In particular, and in a situation when a regulator changes from protecting the
firm to promoting change, the consistency between resource allocations and the official con-
cept of corporate strategy decreases when regulatory involvement increases. (2) Internal
alignments are contingent upon the perceived opportunity structure of a regulatory initiative.
The recruitment of leukocytes from the circulation into tissues requires leu-kocyte migration through the vascular endothelium. The mechanisms by
which leukocytes attach and firmly adhere to the endothelial cell surface
have been studied in detail. However, much less is known about the last
step in this process, the diapedesis of leukocytes through the vascular endo-thelium.
The second industry effect analyzed in our paper takes account of the fact that the
human capital of an independent executive can be proxied by the performance of the
company where the non-executive director is employed as an executive director.
One particular issue with relating director quality to firm performance is that the latter
may be influenced by a variety of factors beyond managerial control, such as an
overall economic downturn or industry shock. Firm performance is therefore a very
noisy measure of director quality. ...
The audit committee should seek reassurance that the auditors and their
staff have no family, financial, employment, investment or business
relationship with the company (other than in the normal course of
business). The audit committee should seek from the audit firm, on an
annual basis, information about policies and processes for maintaining
independence and monitoring compliance with relevant requirements,
including current requirements regarding the rotation of audit partners
The soluble, cytoplasmic NAD
-reducing [NiFe]-hydro-genase fromRalstonia eutrophais aheterotetrameric enzyme
(HoxFUYH) and contains two FMN groups. The purified
oxidized enzyme is inactive in the H2-NAD
can be activated by catalytic amounts of NADH. It was
discovered that one of the FMN groups (FMN-a) is selec-tively released upon prolonged reduction of the enzyme
with NADH. During this process, the enzyme maintained
its tetrameric form, with one FMN group (FMN-b) firmly
bound, but it lost its physiological activity – the reduction of
by H2. ...