Flexible structures

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  • With many 'flexible' structures such as large span bridges, tall buildings, towers, cable roofs, etc., being built, the need to understand the dynamics behavior of structures has become a necessity for many engineers. The recent problems with the millinium bridge is simply another reminder. The many devastating earthquakes in many parts of the world leading to severe loss of life in densely inhabited urban areas alos has underlined the need for a fundamental understanding of structural behavior.

    pdf460p aries23 29-09-2012 57 23   Download

  • Two structures of monomeric methionyl-tRNA synthetase, fromMycobac-terium smegmatis, in complex with the ligands methionine⁄adenosine and methionine, were analyzed by X-ray crystallography at 2.3 A˚ and at 2.8 A˚ , respectively. The structures demonstrated the flexibility of the multidomain enzyme. A new conformation of the structure was identified in which the connective peptide domain bound more closely to the catalytic domain than described previously.

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  • The NS2B–NS3 protease complex is essential for the replication of dengue virus, which is the etiologic agent of dengue and hemorrhagic fevers, dis-eases that are a burden for the tropical and subtropical areas of the world. The active form of the NS3 protease linked to the 40 residues of the NS2B cofactor shows highly flexible and disordered region(s)...

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  • The divalent metal transporter (DMT1) is a 12-transmem-brane domain protein responsible for dietary iron uptake in the duodenum and iron acquisition from transferrin in peripheral tissues. The transmembrane domain 4 (TM4) of DMT1 has been shown to be crucial for its biological function. Here we report the 3D structure and topology of the DMT1-TM4 peptide by NMR spectroscopy with simulated annealing calculations in membrane-mimetic environments, e.g. 2,2,2-trifluoroethanol and SDS micelles.

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  • In this paper we sketch an approach for Natural Language parsing. Our approach is an example-based approach, which relies mainly on examples that already parsed to their representation structure, and on the knowledge that we can get from these examples the required information to parse a new input s e n t e n c e . In our approach, examples are annotated with the Structured String Tree Correspondence (SSTC) annotation schema where each SSTC describes a sentence, a representation tree as well as the correspondence between substrhzgs in the sentence and subtrees in the representation tree. ...

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  • Robust natural language interpretation requires strong semantic domain models, "fall-soff" recovery heuristics, and very flexible control structures. Although single-strategy parsers have met with a measure of success, a multi.strategy approach is shown to provide a much higher degree of flexibility, redundancy, and ability to bring task-specific domain knowledge (in addition to general linguistic knowledge) to bear on both grammatical and ungrammatical input. A parsing algorithm is presented that integrates several different parsing strategies, with case-frame instantiation dominating. ...

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  • The NMR solution structures of NTX-1 (PDB code 1W6B and BMRB 6288), a long neurotoxin isolated from the venom ofNaja naja oxiana, and the molecular dynamics simulation of these structures are reported. Calculations are based on 1114NOEs, 19 hydrogen bonds, 19 dihedral angle restraints and secondary chemical shifts derived from 1 Hto 13 C HSQC spectrum. Similar to other long neurotoxins, the three-finger like structure shows a double and a triple strandedb-sheet aswell as some flexible regions, particularly at the tip of loop II and the C-terminal tail....

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  • The approach is designed to achieve good, i.e. accurate and flexible, indexing by identifying index term sources in the meaning representations built by a powerful general purpose analyser, and providing a range of text expressions constituting semantic and syntactic variants for each term concept. Indexing is seen as a legitimate form of shallow text processing, but one requiring serious semantically based language processing, particularly to obtain well-founded complex terms, which is the main objective of the project described. ...

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  • Nordic Fixed Income Derivatives are traded and cleared in a unique market structure. Trades in fixed income derivatives are reached through bilateral negotiations between buyers and sellers, and reported to NASDAQ OMX Derivatives Markets for central counterparty clearing. NASDAQ OMX Derivatives Markets becomes the counterparty to both the buyer and seller, i.e. central counterparty (CCP) clearing. This structure combines the advantages of a cleared market, with the flexibility and the secured liquidity of a market maker driven market....

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  • After providing the basic background in electromagnetic theory necessary to utilize the software, the author of Ebook Antenna and EM Modeling with Matlab describes the benefits and many practical uses of the Matlab. Sergey Makarov's text utilizes the widely used Matlab(r) software, which offers a more flexible and affordable alternative to other antenna and electromagnetic modeling tools currently available.

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  • The development and deployment of NEMS and MEMS are critical to the U.S. economy and society because nano- and microtechnologies will lead to major breakthroughs in information technology and computers, medicine and health, manufacturing and transportation, power and energy systems, and avionics and national security.

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  • The book "Wind Tunnels and Experimental Fluid Dynamics Research" is comprised of 33 chapters divided in five sections. The first 12 chapters discuss wind tunnel facilities and experiments in incompressible flow, while the next seven chapters deal with building dynamics, flow control and fluid mechanics. Third section of the book is dedicated to chapters discussing aerodynamic field measurements and real full scale analysis (chapters 20-22).

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  • As SIAP notes, the organizational structure of many arts groups and institutions makes them ideal leverage points for local, regional and even global connections. They are flexible organizations that function across a range of applications and relationships; they are linked to local and non-local consumers and suppliers; they utilize horizontal business alliances to enrich their workforce, business offerings and customer base.

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  • DotNetNuke 5.4 is a powerful and flexible content management system for building websites. It comes with many features for publishing content, including tools to create Blogs, Banner Advertising, News Feeds, and much more. The chapters in this book provide example recipes that will show how to download, install, configure, and customize DotNetNuke with your own plugin modules.

    pdf432p nguoidanden 03-07-2013 37 6   Download

  • Filers categorized over half of the subjects as policyholders of either the insured, the beneficiary, the payer, or the applicant. The next largest category of subjects was the applicant or owner of an annuity. Consistent with data from all other financial services industries, insurance compa- ny filers most commonly cited “BSA/Money Laundering/Structuring” as the charac- terization of suspicious activity. Structuring, where larger transactions are broken into smaller exchanges, is consistent with an attempt to avoid currency reporting requirements. ...

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  • The evidence in this paper documents that the similarities between banks’ and non- financial firms’ capital structure may be greater than previously thought. Specifically, this paper establishes five novel and interrelated empirical facts. First, standard cross-sectional determinants of firms’ capital structures also apply to large, publicly traded banks in the US and Europe, except for banks close to the minimum capital requirement.

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  • The ability to conduct research independently, accurately, and effectively plays a fundamental role in college and the workplace. Research skills are critical tools for acquiring, extending, and sharing knowledge in academic and workplace settings, and students must be able to determine when and how to conduct and document research.

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  • The way the project is managed and executed is the key to its success. The involvement of the right people for data capture and decision making is also crucial. It is necessary to identify and recruit these people at the start of the project and to define the project organization structure. It is also necessary to establish the procedures that will be used by the people in the Project Organization Structure to carry out and control the project work.

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  • This studydescribesamodifiedcolorimetricassay foruricase activity in flexible 96-well microtiter plates using the uricase/ uric acid/horseradish peroxidase/4-aminoantipyrine/3,5-dichloro-2-hydroxybenzene sulfonate colorimetric reaction. The utility of this assay was demonstrated in a screen for mutant uricase enzymes derived from theuricasegene of the thermophilic bacteriumBacillus subtilisby a modified stag-gered extension process (StEP) mutagenesis. AnEscherichia coli library of StEP-derived uricase mutant clones was screened yielding two identical active mutanturicasegenes....

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  • Whatever the debate about its nature and causes, almost all observers would agree that inner-city poverty is multidimensional, extraordinarily complex, and difficult to under- stand. Various disciplines and policy frameworks give rise to very different notions of poverty and of its sources. To economists, it is an issue of labor markets, productivity, incentives, human capital, and choice. Sociologists and anthropologists tend to emphasize social status and relations, behavior, and culture. For social psychologists, the issues may include self-image, group membership, and attitudes.

    pdf94p doidieumuonnoi 11-06-2013 17 4   Download

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