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Intrachromosomal triplications (TRP) can contribute to disease etiology via gene dosage effects, gene disruption, position effects, or fusion gene formation. Recently, post-zygotic de novo triplications adjacent to copynumber neutral genomic intervals with runs of homozygosity (ROH) have been shown to result in uniparental isodisomy (UPD).

14p vibransone 28-03-2024 3 2   Download

Ebook "Electrochemistry of immobilized particles and droplets: Experiments with three-phase electrodes (2nd edition)" is still the only one detailing strategies for solid state electroanalysis. It also features the specific potential of the techniques to use immobilized particles (for studies of solid materials) and of immobilized droplets of immiscible liquids for the purpose of studying the three-phase electrochemistry of these liquids.

341p tudohanhtau1006 29-03-2024 2 1   Download

Ebook "Quadruplex nucleic acids (Topics in Current chemistry, Volume 330)" includes descriptions of two physical chemical approaches that provide mechanistic details of quadruplex reactions. Kinetic studies that unravel the mechanism of tetramolecular quadruplex assembly are presented by the team from the Mergny laboratory, studies that may be most relevant for the nanotechnology community.

285p coduathanh1122 27-03-2024 1 1   Download

Ebook "Viral entry into host cells" for a virus to invade a host cell it needs to penetrate the physical barrier imposed by the plasma membrane. Viruses have evolved specialized surface proteins to meet this challenge. These proteins facilitate delivery of the viral genetic information into the host cell by either fusing the viral envelope with a host cell membrane or by forming membrane pores. Membrane fusion and pore formation critically depend on the engagement of host cell receptors and receptor choice is a key determinant of viral tropism.

213p cotieubac1004 15-03-2024 0 0   Download

Part 2 book "Chemical engineering of polymers - Production of functional and flexible materials" includes content: Study of temperature dependence of specific resistance of nickel tungsten coating on copper; topology of formation of latexes in heterogeneous static monomer water systems; synthesis and research of some phtalocyaninic dyes with Cu, Zn for testing in the systems of solar cells type; polymeric recording media based on carbazole containing copolymers and benzoxyphthalocyanines of transition metalsnment,... and other contents.

246p muasambanhan09 16-03-2024 1 1   Download

Ebook "Cell polarity 1: Biological role and basic mechanisms" provides a state-of-the art overview on the most relevant aspects of cell polarity. Volume 1 addresses cell polarity and cell migration (front-rear polarity), cell polarity and barrier formation (apico-basal polarity) and neuronal polarity. It particularly focuses on cell polarity at the molecular level and the underlying molecular mechanisms. It also elaborates the common principles and mechanisms that regulate cellular polarization in different cell types and contexts.

396p manmanthanhla0201 26-02-2024 3 1   Download

Ultraviolet B (UVB) radiation is directly related to sunburn and other visible changes on the skin surface, including discoloration and skin carcinoma. This study investigates the influence of UVB rays (wavelength from 290 - 320nm) on the formation of cancerous tissues and also shows the differences between abnormal and normal tissue.

10p vibego 02-02-2024 1 0   Download

Ebook "The sticky synapse: Cell adhesion molecules and their role in synapse formation and maintenance" are responsible for the functional differences between the various types of neuronal synapses, have become one of the central themes of modern neurobiology. It is becoming increasingly clear that a misregulation of synaptogenesis and synaptic remodeling and dysfunctional neuronal synapses are at the heart of several human diseases, both neurological disorders and psychiatric conditions.

451p manmanthanhla0201 27-02-2024 3 1   Download

Ebook Developmental neurobiology: Part 2 includes content: Cell determination and early differentiation, neuronal survival and programmed cell death, synaptic formation and reorganization,…and other contents.

199p longtimenosee03 01-02-2024 2 0   Download

Ebook "Wood and tree fungi: Biology, damage, protection, and use" provides an up-to-date overview of the various wood and tree fungi that damage trees, lumber, and timber, with special focus given to identification, prevention, and remediation techniques. The final section focuses on the positive effects of wood-inhabiting microorganisms, covering past and classical methods like myco-wood, mushroom cultivation, biological pulping, and "palo podrido", as well as recent biotechnological processes.

336p tachieuhoa 28-01-2024 2 2   Download

In ebook "The Mycota: A comprehensive treatise on fungi as experimental systems for basic and applied research (Volume I: Growth, differentiation and sexuality)" major topics of the first section include dynamic intracellular processes, apical growth, hyphal fusion, and aging. The second section analyses autoregulatory signals, pheromone action, and photomorphogenesis and gravitropism abiotic signals.

454p tachieuhoa 28-01-2024 4 2   Download

Ebook "Genomics and molecular genetics of plant-nematode interactions" reviews developments in the molecular biology of plant-nematode interactions that have been driven by the application of genomics tools. The book will be of interest to postgraduate students and to researchers with an interest in plant nematology and/or plant pathology more generally.

563p tachieuhoa 28-01-2024 4 2   Download

Part 1 book "Essentials of domestic animals embryology" includes content: History of embryology, cellular and molecular mechanisms in embryonic development, comparative reproduction, gametogenesis, fertilization, embryo cleavage and blastulation, gastrulation, body folding and coelom formation, neurulation, comparative placentation, development of the central and peripheral nervous system, eye and ear, development of the blood cells, heart and vascular system.

222p muasambanhan04 11-01-2024 6 1   Download

Part 1 book "Mouse cell culture - Methods and protocols" includes content: The culture of mouse embryonic stem cells and formation of embryoid bodies; derivation of primary mouse embryonic fibroblast (PMEF) cultures; embryonic skeletal muscle microexplant culture and isolation of skeletal muscle stem cells; ... and other contents.

119p muasambanhan04 07-01-2024 2 1   Download

In ebook "Cancer signaling: From molecular biology to targeted therapy" the first part gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells.

357p lucchinguyen 28-12-2023 3 2   Download

Ebook "Bone metastases from prostate cancer: Biology, diagnosis and management" presents up-to-date information on one of the hottest topics in prostate cancer, namely bone metastases. The most recent developments with respect to biology, pathology, diagnosis, and treatment are described, providing readers with an excellent understanding of the mechanisms of metastasis formation, the characteristics of metastases, their aggressiveness, and prognostic factors for treatment response.

293p lucchinguyen 28-12-2023 5 2   Download

Ebook "Cell cycle synchronization: Methods and protocols (Second edition)" provides detailed protocols on the theoretical background of cell cycle synchronization procedures and instructions on how to implement these techniques. The chapters in Cell Cycle Synchronization: Methods and Protocols, Second Edition cover subjects such as: physical fractionations including centrifugal elutriation of healthy and apoptotic cells, and nuclei of mammalian cells; large scale mitotic cell synchronization; chromosome formation during fertilization in eggs;...

345p lucchinguyen 28-12-2023 5 2   Download

Ebook "Cancer stem cells: Methods and protocols" comprehensive collection of methods, protocols, and procedures used for the identification, characterization, and selection of cancer stem cells. These include surface marker expression, side population, spheres formation, ALDH activity, and numerous others.

224p lucchinguyen 28-12-2023 4 2   Download

Ebook "Disease gene identification: Methods and protocols (Second edition)" presents detailed laboratory procedures in an easy to follow format that can be carried out with success by investigators lacking previous exposure to a specific research method. Chapter guide readers through the application of molecular approaches to disease gene identification and overviews, and case studies are also presented.

396p lucchinguyen 28-12-2023 5 2   Download

In this study, we found that LINC00852 was highly expressed in the tissue of prostate cancer using quantitative reverse transcription PCR (qRT-PCR). CCK-8 assay, colony formation experiment, Transwell migration and invasion experiments were performed to prove that the up-regulation of LINC00852 could promote the proliferation, migration and invasion of prostate cancer cells in vitro.

13p vileonardodavinci 23-12-2023 3 2   Download