Understanding the High-Functioning Alcoholic represents the untold story of millions
of alcoholics. The goal of this book is to allow society to see that alcoholics
all suffer from the same disease, but that it may manifest in different ways.
The homeless person and the high-powered executive can both be alcoholics—
alcoholism does not differentiate among socioeconomic class, education level,
and appearance. However, because the high-functioning alcoholic (HFA) has
the ability to perform and succeed, the treatment often comes too late or not at
This book is the outcome of many years of study. With the exception of a few quotations, none of the material
has ever before appeared in any book. The writer has been indebted for years past to many of the physicians
mentioned in the following pages for copies of pamphlets and magazines, and for newspaper articles, bearing
upon the medical study of alcohol.
Agency theory argues that there are costs associated with the separation of
ownership and control in publicly held companies. The agency model proposes that
non-executive directors are an effective means of monitoring executive directors and
that they are able to change the behaviour of the executive directors so that
shareholder interests are pursued (Fama 1980; Fama and Jensen 1983; Hermalin
and Weisbach 2003).
Health literacy is “the degree to which individuals can obtain, process, and understand the basic health information and services they need to make appropriate health decisions.” It represents a constellation of skills necessary for people to function effectively in the health care environment and act appropriately on health care information. These skills include the ability to interpret documents, read and write prose (print literacy), use quantitative information (numeracy), and speak and listen effectively (oral literacy).
Prescribed medication taken in conjunction with alcohol can cause adverse side effects
and generally, older people are advised not to drink when they are taking other drugs.
Problems caused by using alcohol and other drugs concurrently may include a diminished
effect of the drugs in an individual who drinks regularly and the increased sensitivity to
drugs conferred by malnutrition and severe liver damage, for example cirrhosis. Alcohol in
moderate amounts can depress the rate of drug metabolism so that the action of some
drugs is exaggerated, such as benzodiazipines.
This primary text-book of applied physiology follows a natural order of treatment. In each subject elementary
anatomical facts are presented in a manner which impresses function rather than form, and from the form
described derives the function. The facts and principles are then applied to everyday life. Anatomy and pure
physiology make clear and fix hygienic points, while applied physiology lends interest to the otherwise dry
facts of physiology and anatomy.
This book investigates whether or not there is a causal link between personality traits and the development of alcohol abuse. Findings suggest that there is such a link: people who are inclined toward sensation-seeking are likely to consume more alcohol, and those who show high levels of psychotic and/or antisocial behavior are more inclined to have alcohol problems. The authors successfully develop and validate a measure of the Addiction-Prone Personality.
Pyruvate decarboxylase is a key enzyme in organisms whose energy metab-olism is based on alcoholic fermentation. The enzyme catalyses the nonoxi-dative decarboxylation of 2-oxo acids in the presence of the cofactors
thiamine diphosphate and magnesium ions.
The primary objective of the Working Group in developing recommendations for
nutrition principles for foods marketed to children has been the promotion of children’s
health through better diet, with particular – but not sole – emphasis on reducing the incidence
of childhood obesity.
After a limited physical examination, palpable FNAB may be performed as clinically indicated.
The operator should wear examination gloves as described in standard precautions.
should be cleansed with an alcohol swab prior to puncture for superficial FNAB. For percutaneous
biopsy of deep lesions, sterile or aseptic technique is used.
Local anesthesia may be used for palpable lesions at the preference of the operator and the patient,
but is usually used for percutaneous radiologically guided needle biopsies.
In preparing this, his latest volume, the author found himself embarrassed from the beginning, because of the
large amount of material which came into his hands, and the consequent difficulty of selection and
condensation. There is not a chapter which might not have been extended to twice its present length, nor a fact
stated, or argument used, which might not have been supplemented by many equally pertinent and conclusive.
The extent to which alcohol curses the whole people cannot be shown in a few pages: the sad and terrible
history would fill hundreds of volumes.
The function of the Basal Ganglia is a subject of increasing prominence, not only among neuroanatomists, neurobiologists, cognitive-scientists and psychiatrists, but also among clinical ergonomists, rehabilitation, internal medicine and public health medics. This volume is the first of its kind. Scientists of diverse backgrounds join to explore issues about the Basal Ganglia from multiple angles. Basal Ganglia - An Integrative View explores the Basal Ganglia from diverse perspectives, sometimes as starting point others as end of diverse pathologies....
Alcohols are synthesized by a wide variety of methods, and the hydroxyl group may be converted to most other functional groups. For these reasons, alcohols are versatile synthetic intermediates. In this chapter, we discuss the physical properties of alcohols and summarize the methods used to synthesize them.
Chapter 11 - Reactions of Alcohols. Alcohols are important organic compounds because the hydroxyl group is easily converted to almost any other functional group. In Chapter 10, we studied reactions that form alcohols. In this chapter, we seek to understand how alcohols react and which reagents are best for converting them to other kinds of compounds.
The high-level Commission on Information and Accountability for Women’s and Children’s
Health included among its 10 recommendations one that is specific to improving
measurement of maternal (and child) deaths. This recommendation requires that “by 2015,
all countries have taken significant steps to establish a system for registration of births,
deaths and causes of death, and have well-functioning health information systems that
combine data from facilities, administrative sources and surveys”.
ADH1 and ADH4 are the major alcohol dehydrogenases
(ADH) in ethanol and retinol oxidation. ADH activity and
protein expression were investigated in rat gastrointestinal
tissuehomogenates by enzymatic andWesternblot analyses.
In addition, sections of adult rat gastrointestinal tract were
examined byin situ hybridization and immunohistochem-istry.ADH1andADH4weredetectedalong thewhole tract,
changing their localization and relative content as a function
of the area studied.
Mammalian alcohol dehydrogenases (ADH) 3 form a com-plex enzyme system based on amino-acid sequence, func-tional properties, and gene expression pattern. At least four
mouseAdhgenes are known to encode dierent enzyme
classes that share less than 60% amino-acid sequence iden-tity. Two ADH-containing and overlapping C57BL/6
bacterial arti®cial chromosome clones, RP23-393J8 and
-463H24, were identi®ed in a library screen, physically
mapped, and sequenced.
Worldwide consumption in 2005 was equal to 6.13 litres of pure alcohol consumed per
person aged 15 years or older. A large portion of this consumption – 28.6% or 1.76 litres
per person – was homemade, illegally produced or sold outside normal government
controls. However, despite widespread consumption, a higher percentage of people
currently do not drink at all. Almost half of all men and two thirds of women have not
consumed alcohol in the past year.
Other beverages than wine, beer and spirits are consumed mostly in sub-Saharan Africa,
which has generally low alcohol use levels. In the rest of the world – including most of
the Western Hemisphere, northern Europe, many African countries and Australia – the
most consumed beverage in terms of litres of pure alcohol is beer.
Globally, more than 45% of total recorded alcohol is consumed in the form of spirits,
predominantly in the South-East Asia and Western Paciﬁ c (WPR) regions (Table 3).
Approximately 36% of total recorded alcohol is consumed in the form of beer. ...
A compound consisting of an alkyl group and the functional group -OH is an alcohol. The
identity of an individual alcohol depends on the identity of R, the alkyl group. For example, when
R is the methyl group, we have CH30H. This is methyl alcohol or methanol, also known as wood
alcohol. It is highly toxic and can cause blindness or even death in relatively small doses. When R
is the ethyl group, we have CH3CH20H. This is ethyl alcohol or ethanol. Ethanol is the alcohol in
alcoholic beverages. When R is the isopropyl group, we have (CH3)2CHOH. This is isopropyl alcohol.