Genes including toll

Xem 1-20 trên 45 kết quả Genes including toll
  • Jules Hoffmann made his pioneering discovery in 1996, when he and his co-workers investigated how fruit flies combat infections. They had access to flies with mutations in several different genes including Toll, a gene previously found to be involved in embryonal development by Christiane Nüsslein-Volhard (Nobel Prize 1995). When Hoffmann infected his fruit flies with bacteria or fungi, he discovered that Toll mutants died because they could not mount an effective defense.

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  • Each year , approximately 71,500 women in the United States are diagnosed with a gynecologic cancer. While all women are at risk for developing gynecologic cancers, few will ever develop one. Still, it is important to know the signs because there is no way to know for sure who will get a gynecologic cancer. The information included in this booklet will help you recognize any warning signs, so you can ask your health care provider about them. These signs and symptoms often are related to something other than gynecologic cancer. But it is...

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  • Recent DCF analysis highlighted the importance of improved national aid information management systems to better track effective development cooperation targets, including on gender equality and the empowerment of women, and to make a wide range of timely and forward-looking information (on disbursements, forecasts, progress on results, and gender issues) widely available to all stakeholders for accountability purposes.

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  • PHI has often financed the delivery of larger treatment volumes by offering higher payments to providers. Financial incentives linked to payment mechanisms exert a direct impact upon doctors’ productivity.32 This has contributed to a growth in the volumes of private hospital treatments in several countries where doctors have both public and private sector engagements, as in Australia and Ireland (Colombo and Tapay, 2003 and 2004b).

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  • This report provides an overview of the statutory framework, key players, infrastructure, resources, tools, and operations associated with enforcement and compliance of the major pollution control laws and regulations administered by EPA. It also outlines the roles of federal (including regional offices) and state regulators, as well as the regulated community. Understanding the many facets of how all federal pollution control laws are enforced, and the responsible parties involved, can be challenging.

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  • Estrogen receptors and serotonin receptors coexist in cells in a wide variety of tissues, and this critical review of the literature suggests that many of E2's effects may be medi- ated by changes in the actions of serotonin (5HT). Serot- onin is usually considered to be a neurotransmitter, but surprisingly, only 1% of serotonin in the human body is found in the CNS [4].

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  • Note, however, that the securities laws of applicable non-U.S. jurisdictions, which are beyond the scope of this article, must be complied with. Although Regulation S provides a complex hierarchy of offering types and the corresponding requirements for each, the basic principle is that there must be no “directed selling efforts” in (toward) the United States.

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  • We included studies that evaluated the performance of the most recent generation of commercial, RD1 antigen-based IGRAs (QFT-GIT and T-SPOT) among adults (age $15 years) with suspected active pulmonary tuberculosis or confirmed tuberculosis in low- and middle-income countries [22]; the World Bank Country Classification was considered as a surrogate for national tuberculosis incidence. HIV infection was established either by documented serological testing or self-report.

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  • The second of these new initiatives launched in September of 2008 is a similar partnership between an organization called World of Good, Inc. and online auction giant eBay. This collaboration is known as World of Good by eBay and their tagline is “Where your Shopping Shapes the World.” The partnership was formed with the idea that there is a growing consumer need for trusted information, and for transparency into how and where products are made. Both World of Good and Worldstock.

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  • Coordination means, at a minimum, that programming within and among U.S. agencies takes advantage of each agency’s strengths, avoids duplication, and increases the efficiency and effectiveness of each dollar spent. Better coor- dination of programs and delivery platforms provides opportunities to strengthen the integration of health services at the point of delivery to meet more of the health care needs of individuals, as well as ensure satisfaction with and increase demand for those services.

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  • Public employment services and employers face a major challenge with the scale of unemployment in Europe, in particular among young persons. To boost the employability levels is key to re-launch growth, taking also into consideration vulnerable groups. The potential for job creation in sectors such as the green economy, ICT, health and is not fully exploited. Education and training systems are not keeping up with changing labour market needs – resulting in shortages in key areas like science, mathematics and e-skills.

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  • With regard to the destination of the invested funds in terms of sector allocation, we are restricted to use data obtained about business angel networks (see EBAN, 2010c). While it is generally difficult to apply insights gained from networks to the overall BA market, it might be fair to assume such sector data to be representative for the market in general.

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  • An analysis of the journals revealed that the teachers experimented quite freely with different teaching styles. Sometimes, they were very direct in giving students instruc- tions on how to revise their drafts. At other times they were more open to student input and negotiation of meaning.

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  • There is a global trend of falling household sizes over time, though an international comparison quickly reveals that this reduction is not uniform across countries. Apart from tradition, economic variables are influential in determining how many people live together in one household. We have tried to capture this relationship with a pooled cross-section of 38 countries and data for different years between 1960 and 2006. The dependent variable is the average household size.

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  • This plan sets out our high level business priorities and delivery plans for 2012-2013, not only to provide core services to offenders in prison and on probation in England and Wales, but also to continue to improve the way we work, to achieve better outcomes for the public at less cost to the taxpayer. The reforms and activities in this plan are part of the wider Ministry of Justice Transforming Justice programme, to deliver a justice system which is more effective, less costly, and more responsive to the public.

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  • This paper focuses on the issue of reporting errors in subjective health measures. We state assumptions under which we can use relatively simple methods to assess the relative importance of state dependent reporting errors in individual responses to health questions. The methods proposed in this paper could be used directly to purge reporting biases from the subjective health responses to generate unbiased measures of health that can be used in subsequent analyses. The methods are applied on Dutch data , It may be clear from the discussion in...

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  • The resulting view, that financial markets can be subject to inherent instability, induces governments to intervene to provide depositor protection in some form or other. Explicit deposit insurance is one approach, while an explicit or implicit deposit guarantee is another. In either case, general prudential supervision also occurs to limit the risk incurred by insurers or guarantors. To control the incentives of bank owners who rely too heavily on government funded deposit insurance, governments typically enforce some control over bank owners.

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  • To break this chicken-and-egg problem, thus enabling more flexible informa- tion access, we have created a web browser extension called Piggy Bank that lets users make use of Semantic Web content within Web content as users browse the Web. Wherever Semantic Web content is not available, Piggy Bank can invoke screenscrapers to re-structure information within web pages into Semantic Web format. Through the use of Semantic Web technologies, Piggy Bank provides direct, immediate benefits to users in their use of the existing Web.

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  • It is estimated that NRs. 0.5 billion per year in tourism revenue is lost due to air pollution in Kathmandu valley (World Bank, 1997). Findings of a survey conducted among 1,702 tourists between May and June 2001 by MARG Nepal indicate that the quality of air is the number one area where tourists feel improvement is needed. This shows that Kathmandu’s poor transportation system and pollution is not only affecting human health and environmental quality, but also the tourism industry (Business Age, 2001).

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  • He points to his fi rm’s work for Microsoft Corp.’s Xbox gaming system. “We were engaging with bloggers and fans eight to 10 months before the ads broke. “Our job is no longer doing a press conference to break the ads—we are building engagement with enthusiasts to create a runway of credibility for a new brand or campaign.” Under the old model of public relations, the job of a PR fi rm was to get a story in the newspaper. Says Mr. Stockman, “If we got a piece in The Wall Street Journal, we’d give ourselves high fi ves. Now, if you get a piece in the Journal, you have...

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