Genetic basis

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  • Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: The complex genetic basis of simple behavior...

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Genetic mapping of wild introgressions into cultivated peanut: a way toward enlarging the genetic basis of a recent allotetraploid

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  • Human genetics is the medical field with the most rapid and, one can say, overwhelming progress. The medical practitioner constantly needs to be up-to-date on the newest developments in his field. The diversity and rapid dynamics of advancements in genetics can sometimes overcome the assimilation possibilities of one person; thus, overspecialization for narrowing and deepening the research focus is needed. Consequently, expert opinion is much valued. This book aims to provide exactly such opinions regarding several genetic diseases.

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  • Chapter 19 - Variation and selection in populations. This chapter involves the study of how genetic laws impact the genetic makeup of a population. Mendelian principles are the basis for the Hardy-Weinberg law which allows one to calculate allele and genotype frequencies from one generation to the next. The Hardy-Weinberg law can be used only if other forces are not acting on the allele frequency. Those forces include selection, migration, mutation, and population size.

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  • Crossing-over and genetic recombination. During chiasma formation, either of the two sister chromatids on one chromosome pairs with one of the chromatids of the homologous chromosome. Genetic recombination occurs through crossing-over and results in recombinant and nonrecombinant chromosome segments in the gametes. Together with the random segregation of the maternal and paternal chromosomes, recombination contributes to genetic diversity and forms the basis of the concept of linkage.

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  • Periodontal disease progression is episodic in nature on a tooth site level, but more recently, it has been realized that it is principally patient-based rather than site-based (Zia et al., 2011); the host related risk factors could be the key to better understand disease evolution. The available evidence shows that important risk factors for periodontal disease relate to poor oral hygiene, tobacco use, excessive alcohol consumption, stress, and diabetes mellitus (Laurina et al., 2009; Taylor & Borgnakke, 2008).

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  • Plant response to reduced water availability and other abiotic stress (e.g. metals) have been analysed through changes in water absorption and transport mechanisms and also by molecular and genetic approach. A relatively new aspects of fruit nutrition are presented in order to provide the basis for the improvement of some fruit quality traits. The involvement of hormones, nutritional and proteomic plant profiles together with some structure/function of sexual components have also been addressed.

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  • Inflammatory bowel disease research is changing. Progress in defining and treating these diseases is advancing in lock step with the furious pace of technological advances that continue to refine the tools of discovery. With sequencing of the entire genome completed, genetics research is providing direction for molecular and immunological in vivo and in vitro investigation, which in turn directs the development of targeted therapeutics.

    pdf761p hyperion75 18-01-2013 33 10   Download

  • Tham khảo sách 'novel insights on chronic kidney disease, acute kidney injury and polycystic kidney disease', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • Expressiveness refers to the ability of the event notification service to provide a powerful data model with which to capture information about events, to express filters and patterns on notifications of interest, and to use that data model as the basis for optimizing notification delivery.

    pdf104p nhacchovina 22-03-2013 23 7   Download

  • To be effective, risk management needs to be an ongoing and meaningful element in the management of the plan. The plan needs to do more than a ‘tick and flick’ exercise at the commencement of the project; it needs to identify who is responsible for reviewing risks on a regular basis, and how this will be done.

    pdf27p tay_thi_le 21-02-2013 19 6   Download

  • How and when such theoretical uncertainty will translate into actual market movements will depend on market dynamics. Because of extreme monetary ease, short-term interest rates have been close to zero for some time and markets expect policy rates to remain low. The yield curve is quite steep yet long-term interest rates are very low by historical standards. Graph 4 shows that the US dollar term spread has been around 250–350 basis points since mid-2009.

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  • Since publication of the first edition of CRC Desk Reference of Clinical Pharmacology in 1998, dramatic discoveries in molecular medicine, along with rapid concomitant technological advances, have revolutionized the diagnosis and treatment of a broad range of human diseases with new medications. Given the rapid pace of new discovery, genetic- and cell-based therapeutics have now become a common part of the physicians’ armamentarium. A few examples will be given concerning two leading causes of death—cancer and cardiovascular diseases—to illustrate this....

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  • The year 2004 witnessed what was probably the most highly publicized fingerprint error ever exposed: the case of Brandon Mayfield, an Oregon attorney and Muslim convert who was held for two weeks as a material witness in the Madrid bombing of March 11, 2004, a terrorist attack in which 191 people were killed. Mayfield, who claimed not to have left the United States in ten years and did not have a passport, was implicated in this attack almost solely on the basis of a latent fingerprint found on a bag in Madrid containing detonators and explosives in the aftermath of the bombing.

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  • This book provides recent developments and advances in research on Down syndrome. It covers a wide range of topics, including investigations on prenatal diagnosis and screening, genetic counseling, neoplastic disease, congenital heart disease, dentistry and oral health, obesity, molecular genetics and neurological disorders in Down syn‐ drome. It is also a resource for scientists and research workers who wish to learn more about Down syndrome. To date, well over one hundred chromosome syndromes have been reported. Whilst on an individual basis many of these are...

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  • Nitric oxide (NO • ) has been proposed to be a physiological modulator of cell proliferation, able to promote in most cases cell cycle arrest. In this review I explore the molecular basis of this mechanism of action. The mod-ulatory action of NO • on the intracellular concentration of cGMP and the machinery directly involved in the control of cell cycle progression, inclu-ding the expression and activity of diverse cyclins and cyclin-dependent kinases,

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  • Dairies are required to have an NMP to protect water quality from livestock nutrient discharges. Each basic function of the operation, production, collection, storage, transfer, treatment and field application is covered by the plan. The basis for nutrient management is sound agronomic use of solid and liquid manure. The Livestock Nutrient Management Program has inspectors that routinely inspect dairies for compliance with their nutrient management plans and preventing any discharges to surface and ground water....

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  • The Ethiopian Boran breed is one of the cattle breeds widely used in Ethiopia. The breed is well adapted to semi-arid tropical conditions, has a high degree of heat tolerance, is tolerant to many of the diseases prevailing in the tropics and has the ability to survive long periods of feed and water shortage (Ojango et al. 2006). These properties have genetic basis and have been acquired by natural and human selection over generations. They are all essential for successful animal production in the tropics.

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  • The design of b-glycosidases with planed substrate specificity for biotechnological application has received little attention. This is mostly a consequence of the lack of data on the molecular basis of the b-glycosidase specificity, namely data on the energy of the noncovalent interactions in the enzymetransition state complex.

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