Genetic effects

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  • The National Council on Radiation Protection and Measurements (NCRP) was requested by the US Department of Energy (DOE) to review the literature on the effects of radiation on aquatic organisms and develop a document that reviews the present understanding of such effects and provides guidance for a standard for the protection of populations of aquatic organisms.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population...

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  • Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: Genetic effects of static magnetic fields. Body size increase and lethal mutations induced in populations of Drosophila melanogaster after chronic exposure

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  • Tuyển tập các báo cáo nghiên cứu về lâm nghiệp được đăng trên tạp chí lâm nghiệp quốc tế đề tài: Improving models of wood density by including genetic effects: A case study in Douglas-fir...

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  • Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Selection of as grandparental combinations a procedure designed to make use of dominance genetic effects

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  • Population Screening Mass genetic screening programs require tests of high enough sensitivity and specificity to be cost-effective. An effective screening program should fulfill the following criteria: that the tested disorder is prevalent and serious; that it can be influenced presymptomatically through lifestyle changes, screening, or medications; and that identification of risk does not result in undue discrimination or harm.

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  • Harrison's Internal Medicine Chapter 64. The Practice of Genetics in Clinical Medicine Implications of Molecular Genetics for Internal Medicine The field of medical genetics has traditionally focused on chromosomal abnormalities (Chap. 63) and Mendelian disorders (Chap. 62). However, there is genetic susceptibility to many common adult-onset diseases, including atherosclerosis, cardiac disorders, asthma, hypertension, autoimmune diseases, diabetes mellitus, macular degeneration, Alzheimer's disease, psychiatric disorders, and many forms of cancer.

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  • Genetically modified foods and food products derived from genetically engineered organisms are among a number of biotechnological developments intended to improve shelf life, nutritional content, flavor, color, and texture, as well as agronomic and processing characteristics. Although in popular parlance the term genetically modified often is used interchangeably with genetically engineered, in this report genetic modification refers to a range of methods used to alter the genetic composition of a plant or animal, including traditional hybridization and breeding.

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  • General Classes of Cancer Genes There are two major classes of cancer genes. The first class comprises genes that directly affect cell growth either positively (oncogenes) or negatively (tumor-suppressor genes). These genes exert their effects on tumor growth through their ability to control cell division (cell birth) or cell death (apoptosis). Oncogenes are tightly regulated in normal cells. In cancer cells, oncogenes acquire mutations that relieve this control and lead to increased activity of the gene product.

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  • Learners enrolled in all healthcare training programs need to have a basic understanding of medical genetics so that they can successfully transition from students to clinicians. The field of medical genetics is advancing at a fast pace and is becoming increasingly integral to all aspects of medicine. This fact emphasizes the need for every practicing clinician and faculty member to develop an in-depth knowledge of the principles of human genetics, given that they are applicable to such a wide variety of clinical presentations.

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  • The 2005 Declaration discussed above and the Universal Declaration on the Human Genome and Human Rights, 1997 are both resolutions passed in the General Assembly. They have no immediate binding effect. They play a signifi cant role in the formation of customary international law. There are many different forms of law making in international law and although an international convention or a treaty is a source of binding rules, the importance of other methods of formation of international law cannot be underestimated.

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  • Although the main consideration of policy must be the reduction in pollution at source, there has been an increasing recognition that the biosphere is an important sink for many pollutants, with plant canopies being considered more effective than other land uses. Thus, the biosphere provides benefits additional to those associated directly with their aesthetic and wildlife characteristics. Plants facilitate the uptake, transport and assimilation or decomposition of many gaseous and particulate pollutants.

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  • Humidity promotes the growth of moulds Credit: Infrogmation The majority of the health effects linked to dampness and moisture of buildings are those of the respiratory system. They range from irritation of mucous membranes, respiratory symptoms, and infections to diseases such as asthma and allergy. However , it is still not known precisely how dampness leads to these symptoms and which are the main substances responsible. Humidity problems in buildings may originate from leaks, condensation, or the ground.

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  • The betulinic acid (BetA) purified fromPulsatilla chinensis(PC) has been found to have selective inhibitory effects on hepatitis B virus (HBV). In hepatocytes from HBV-transgenic mice, we showed that BetA substantially inhibited HBV replication by downregulation of manganese superoxide dismutase (SOD2) expression, with subsequent reactive oxygen species gen-eration and mitochondrial dysfunction.

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  • Anaemia is a common complication of pulmonary tuberculosis. The precise mechanism of anaemia in pulmonary tuberculosis is not clearly known, but anaemia of inflammation as well as of Fe deficiency has been implicated. Both are common in developing countries. It is extremely difficult to distinguish anaemia of Fe deficiency from anaemia of inflammation with the haematological indices used routinely. Therefore, Fe preparations are usually prescribed for all anaemic patients irrespective of the aetiology. This approach has been questioned.

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  • This study characterized the human apolipoprotein H [APOH; b2-glycopro-tein I (b2GPI)] promoter and its variants byin vitro functional experiments and investigated their relationship with human plasmab2GPI levels. We examined the individual effects of 12 APOHpromoter single nucleotide polymorphisms in the 5¢ flanking region ofAPOH(1.4 kb) on luciferase activity in COS-1 cells and HepG2 cells and their impact on plasma...

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  • In this work we compared two plant ureases, jackbean urease (JBU) and embryo-specific soybean urease (SBU) and a bacterial (Bacillus pasteurii) urease, for kinetic parameters and other biological properties described recently for ureases that are independent of the ureolytic activity. The insecticidal effect of ureases was investigated in feedingtrials with the cotton sucker bug,Dysdercus peruvi-anus (Hemiptera) as an insect model. Contrastingwith B. pasteuriiurease (PBU), both plant ureases presented potent insecticidal activity, with LD50 values of 0.017% (w/w) and 0.

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  • Chapter 8 includes contents: The genetic code, transcription: from DNA to RNA, translation: from mRNA to protein, differences in gene expression between prokaryotes and eukaryotes, a comprehensive example: computerized analysis of gene expression in C. elegans, The effect of mutations on gene expression and gene function.

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  • Chapter 16 - Gene regulation in eukaryotes. The main contents of this chapter include all of the following: Overview of eukaryotic gene regulation, control of transcription initiation, chromatin structure and epigenetic effects, regulation after transcription, a comprehensive example: sex determination in Drosophila.

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  • The National Cancer Institute (NCI) Office of Biorepositories and Biospecimen Research (OBBR) asked the RAND Corporation to identify and analyze existing data on the effects of preanalytical variables on biospecimens used to study genetic and proteomic changes in cancer. The project was broken down into three phases.

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