Xem 1-20 trên 66 kết quả Genomics era
  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Membrane traffic in the post-genomic era...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Assessing the origin of species in the genomic era...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Lipids join the post-genomic era...

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  • Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field.

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  • This book considers diagnosis and treatment of abdominal and thoracic aortic aneurysms. It addresses vascular and cardiothoracic surgeons and interventional radiologists, but also anyone engaged in vascular medicine. The book focuses amongst other things on operations in the ascending aorta and the aortic arch. Surgical procedures in this area have received increasing attention in the last few years and have been subjected to several modifications.

    pdf218p ti_du_hoang 15-08-2012 36 12   Download

  • The Twenty-First Century Physician: Expanding Frontiers The Era of Genomics In the spring of 2003, the complete sequencing of the human genome was announced, officially ushering in the genomic era. However, even before this landmark accomplishment, the practice of medicine had been evolving as a result of the insights gained from an understanding of the human genome as well as the genomes of a wide variety of microbes, whose genetic sequences were becoming widely available as a result of the breathtaking advances in sequencing techniques and informatics.

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  • The chapter provides insight into the early assessment process and the application of precaution, an often poorly described management action rarely captured in peer review literature. The situation surrounding this potential new threat to blood safety was largely resolved in mid-2011 when it was determined that the virus was an artifact from contaminated patient samples and from contamination stemming from a diagnostic test kit widely used by researchers.

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  • It usually looks at cash flow during the hold period of the investment plus the cash flow resulting from the ultimate disposition of the investment property. In these respects it is different from and more sophisticated than Tool Kit #2 Direct Capitalization, which usually limits its focus to annual net incomes without taking into account cash flow, appreciation in value, paying down of mortgages, or ultimate cash flow on disposition.

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  • The explosion of new technologies in the post-genomic era is allowing the study of biological systems on a genome-wide scale, at the main functional genomic levels: (epi)-genome, transcriptome, proteome, endo- and exometabolome, and their interactions. At the same time that these techniques are being applied and refined, the complexity of biological systems is being rediscovered (1) with thousands of components (e.g., genes, transcripts, proteins, metabolites) participating in finely tuned metabolic and regulatory networks.

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  • The impact of biomarkers in present day health care system, health management and healthy life is enormous. Clinicians need them for diagnosis, prognosis, effect of therapeutic intervention, and most importantly, for early detection of a disease. Pharmaceutical industries need them for new drug discovery and drug efficiency test. Regulatory authorities need them for testing toxicity and environmental impact. Epidemiologists need them for population screening and risk factor determination.

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  • Increasing attention has also been given to dissecting and understanding diversity in relation to genes underlying important agronomic traits in a number of crops. Molecular phylogenetics and genetic diversity analysis can help to clarify the taxonomic identity and evolutionary relationships of the wild relatives of crop species. These methods can also help prevent misidentification and carefully plan effective germplasm management strategies.

    pdf414p conquynho32 18-09-2012 33 6   Download

  • Carotenoids are hydrophobic compounds and thereby act as lipophilic antioxidants preventing polyunsaturated fatty acids from oxidative damages. In fact, carotenoids are incorporated into lipid membranes and thus could act as chain-breaking antioxidants by stopping free radical chain reactions (propagation of lipid peroxidation), scavenging lipid peroxyl radicals (LOO•), avoiding the abstraction of allylic hydrogens from neighboring lipids. Inactivation of lipoxygenase activity by carotenoids is also proposed as another mechanism of protection against oxidative stress.

    pdf190p wqwqwqwqwq 23-07-2012 41 5   Download

  • Because the insurance industry employs both captive and independent producers in its various models of product distribution, understanding the insurer-producer relationship is critical when determining the insurer’s responsibility for its appointed producers’ social media communications. As such, if the content of an appointed producer’s social media communication can be attributed to a specific carrier, regulators will also attribute the communication to the carrier.

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  • For the last 100 years, a health care regulatory project enthusiastically endorsed by generations of health policy experts has been encrusting U.S. health care with layer upon layer of increasingly intrusive regulation. Though each regulation may be innocuous in its own right, taken together they have had the unfortunate effect of divorcing patients from spending on their health, creating explosive growth in Wisconsin’s Medicaid budget, and making Wisconsin’s market for hospital services one of the least competitive in the United States.

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  • This guidance is not legally-binding. It represents a synthesis of the information and experience available to the Commission. It is intended as a summary of the current state of the art with respect to best practice on integrated environmental management. The guidance is not intended to be a rigid set of rules to be followed in all circumstances. The mere fact that there is so much diversity between cities across the EU means that no one solution is applicable nor appropriate for all situations.

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  • In terms of detail, the Cairns Group inter alia demands that payments under environmental programs should be less than the extra costs involved in complying. A controversial point could be that the EU’s environmental programs offer income foregone, additional costs as well as the financial incentive necessary to encourage farmers to make agri-environmental undertakings. The new suggestion brought forward by Cairns could thus be seen as an indicator that the Group is considering current practice, like by the EU, as too generous regarding the amount of the overall compensation.

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  • Subsidy rates range from 38% to 67% for policies using either “basic” units or “optional” units. Basic units cover all plantings in a single county of a crop with the same tenant/landlord. Optional units are basic units divided into smaller units by township section. As newly authorized under the 2008 farm bill, a higher subsidy rate (up to 80%) is provided for policies using enterprise units (all land for a single crop in a county, regardless of the tenant/landlord structure). Because the premium for policies using enterprise units is lower (i.e.

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  • Conceptually, the equity method treats the investee company as if it were condensed into one balance sheet item and one income statement item and then merged into the investor company at the proportion owned by the investor. The equity method is sometimes called “one-line consolidation” because it results in the same effect on the investor’s earnings and retained earnings as would result from consolidating the financial statements of the investor and investee companies. It does so without combining both companies’ financial statements.

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  • While structuring financing packages for vital projects is among the most impor- tant roles the federal government plays in infrastructure investment, its activities extend well beyond this role and into research, issuing regulations, awarding grants, environmental protection, and even directly operating and maintaining locks, dams, bridges, and utilities throughout our country. To coordinate all of these activities and maximize the efficiency of federal infrastructure programs, we need a national infrastructure planning council.

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  • The ambiguity in Judd’s sculpture relates to most of his sculptures conforming to box like constructions that rely on the precision of the right angle, the consequence of this is that just as square boxes have four sides, so do his sculptures, and in having four sides they can be said to be made up of parts, no matter how pervasive the quality of the orthogonal and the square are. Further to this, the repetition of squareness without variation can result in a work having little or no aesthetic significance, what is required therefore is the addition of a ‘different’...

    pdf6p yasuyidol 01-04-2013 17 4   Download

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