Genotype encodes

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  • contrast, the solution is defined by data structures that describe the original problem context indirectly and thus, determine the search space within an evolutionary search (optimization process). There exists the analogy in the nature, where the genotype encodes the phenotype, as well. Consequently, a genotype-phenotype mapping determines how the genotypic representation is mapped to the... more

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  • n contrast, the solution is defined by data structures that describe the original problem context indirectly and thus, determine the search space within an evolutionary search (optimization process). There exists the analogy in the nature, where the genotype encodes the phenotype, as well. Consequently, a genotype-phenotype mapping determines how the genotypic representation is mapped to the phenotypic property. In other words, the phenotypic property determines the solution in original problemcontext. ...

    pdf136p contentnew 10-04-2012 94 44   Download

  • In mammals, cytochrome P450 17a-hydroxylase⁄17–20 lyase (CYP17), which is encoded by a single gene, plays a critical role in the production of mineralocorticoids, glucocorticoids and androgens by the adrenal cortex. Two CYP17 isoforms with unique catalytic properties have been identified in the South African Angora goat (Capra hircus), a subspecies that is susceptible to cold stress because of the inability of the adrenal cortex to produce sufficient levels of cortisol.

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  • Lack of functional Fragile X mental retardation protein (FMRP) is the pri-mary cause of the Fragile-mental retardation syndrome in humans. In most cases, the disease results from transcriptional silencing of fragile mental retardation gene 1, fmr1, which encodes FMRP. However, a single mis-sense mutation (I304N) in the second KH domain of FMRP gives rise to a particularly severe case of Fragile X syndrome.

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