Adenine nucleotide translocases (ANTs) are multitask proteins involved in
several aspects of cell metabolism, as well as in the regulation of cell
death⁄survival processes. We investigated the role played by ANT isoforms
1 and 2 in the growth of a human glioblastoma cell line (ADF cells). The
silencing of ANT2 isoform, by small interfering RNA, did not produce sig-nificant changes in ADF cell viability.
Dipetidyl-petidase III is a metallopeptidase involved in a number of physi-ological processes and its expression has been reported to increase with the
histological aggressiveness of human ovarian primary carcinomas. Because
no information regarding the regulation of its expression was available,
experiments were designed to clone, define and characterize the promoter
region of the human dipeptidyl-peptidase III (DPP-III) gene.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: Enhancement of radiosensitivity in human glioblastoma cells by the DNA N-mustard alkylating agent BO-1051 through augmented and sustained DNA damage response...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài:" The c-Met receptor tyrosine kinase inhibitor MP470 radiosensitizes glioblastoma cells...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Radiation Oncology cung cấp cho các bạn kiến thức về ngành y đề tài: " The membrane targeted apoptosis modulators erucylphosphocholine and erucylphosphohomocholine increase the radiation response of human glioblastoma cell lines in vitro...
Living squamous cells are found just below the stratum corneum. These cells have moved
here from the lowest part of the epidermis, the basal layer. The cells of the basal layer, called
basal cells, continually divide to form new keratinocytes. These replace the older
keratinocytes that wear off the skin's surface.
Cells called melanocytes are also found in the epidermis. These skin cells make a brown
pigment called melanin. Melanin gives the skin its tan or brown color. It protects the deeper
layers of the skin from some of the harmful effects of the sun. When skin is exposed...
TheST2gene, which is specifically induced by growth sti-mulation in fibroblasts, encodes interleukin-1 receptor-rela-tedproteins and iswidely expressed in hematopoietic, helper
T, and various cancer cells. However, the physiological as
well as pathological functions of the ST2 gene products are
not yet fully understood. In this study, we analyzed the
expression of theST2gene in human glioma cell lines and
human brain tumor samples with real-time polymerase
The currently available treatment options for glomerular disorders are not optimal
since most of them either respond only partially or poorly so that relapse and
progression is often the rule. Inadequate understanding of the factors underlying the
development and progression of glomerular injury in various clinical scenarios is
primarily responsible for lack of ideal therapies. The section on immune system and
glomerulonephritis has three chapters which basically cover some of the actively
investigated areas. Tetsuhiro Tanaka et al.
In the first section of this book, ‘Retroviral Vector’, chapter one discusses the efficiency
of retroviral DNA integration, the preferences of integration for certain regions, and
advances on integration site selection and gene therapy. Chapter two reviews and
discusses the current cell lines and bioreaction platforms used for production of
retroviral and lentiviral vectors, focusing on the current bottlenecks and future
directions with a particular emphasis in the metabolic constrains.
Today, cancer research is focused on determining how genome and proteome level
information may be useful as tools in prevention, diagnosis, and prognosis. The
development of “omics” technologies, such as proteomics and transcriptomics has
opened new research areas for scientists working on cancer research.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Folate Functionalized Boron Nitride Nanotubes and their Selective Uptake by Glioblastoma Multiforme Cells: Implications for their Use as Boron Carriers in Clinical Boron Neutron Capture Therapy
Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life‐long disorder. It is
characterized by inflammation in the small intestine of genetically predisposed
individuals caused by inappropriate immune response to gluten, a protein enriched in
some of our common grains (wheat, rye and barley). The toxicity of gluten is
manifested by the autoimmune action of T‐lymphocytes on mucosal cells in the small
intestine, disrupting its vital function of absorbing
nutrients from food.
This is not only the most common type of skin cancer, but the most common type of cancer
in humans. About 8 out of 10 skin cancers are basal cell carcinomas (also called basal cell
cancers). They usually develop on sun-exposed areas, especially the head and neck. Basal
cell carcinoma was once found almost entirely in middle-aged or older people. Now it is also
being seen in younger people, probably because they are spending more time out in the sun.
When seen under a microscope, basal cell carcinomas share features with the cells in the
lowest layer of the...
The human prion protein (PrP) is a glycoprotein with a glycosylphosphat-idylinositol (GPI) anchor at its C-terminus. Here we report alternative splic-ing within exon 2 of the PrPgene (PRNP) in the human glioblastoma cell
line T98G. The open reading frame of the alternatively spliced mRNA lacked
the GPI anchor signal sequence and encoded a 230 amino acid polypeptide.
Biopsy (BY-op-see): The removal of cells or tissues for
examination by a pathologist. The pathologist may
study the tissue under a microscope or perform other
tests on the cells or tissue. When only a sample of
tissue is removed, the procedure is called an incisional
biopsy. When an entire lump or suspicious area is
removed, the procedure is called an excisional biopsy.
When a sample of tissue or fluid is removed with a
needle, the procedure is called a needle biopsy, core
biopsy, or fine-needle aspiration.
(BQ) Part 1 book "Brain tumors" presentation of content: Normal tissue, recurrent high grade glioma with radiation changes, gemistocytic astrocytoma, anaplastic astrocytoma, glioblastoma multiforme, granular cell glioblastoma, giant cell glioblastoma, pleomorphic xanthoastrocytoma, pilomyxoid astrocytoma,... and other content.