Milk provides nutritional, immunological and developmental components
for newborns. Whereas identification of such components has been per-formed by targeting proteins and free oligosaccharides, structural and func-tional analyses of the N-glycome of milk glycoproteins are scarce.
Agglutination of red blood cells (RBCs), including chicken RBCs (cRBCs),
has been used extensively to estimate viral titer, to screen glycan-receptor
binding preference, and to assess the protective response of vaccines.
Although this assay enjoys widespread use, some virus strains do not
In response to a request from the National Institutes of Health (NIH), the Food and Drug
Administration (FDA), the U.S. Department of Energy (DOE), and the National Science
Foundation (NSF), the National Research Council convened a committee to assess the
importance and impact of glycoscience, explore the landscape of current research, and
identify the challenges that will need to be addressed to enable the field to move
Expression of the tumor suppressor p16
after stable transfection can
restore the susceptibility of epithelial tumor cells to anoikis. This property
is linked to increases in the expression and cell-surface presence of the
fibronectin receptor. Considering its glycan chains as pivotal signals, we
assumed an effect of p16
This book is simple in its design. Glyconutrition is, I believe, one of the health technologies which is already impacting the health world. It has earned four Nobel Prizes in the last eight offered in the field of medicine, which is a powerful testimony in and of itself. However, glyconutrition is already referred to as one of the top ten technologies which will change our world. That is the position of the prestigious M.I.T.