Hepatic microsomal

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  • Pharmacology can be defined as the study of substances that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes. These substances may be chemicals administered to achieve a beneficial therapeutic effect on some process within the patient or for their toxic effects on regulatory processes in parasites infecting the patient.

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  • Recent studies have suggested that parts of the hepatic activities of diacylglycerol acyltransferase and acyl choles-terol acyltransferase are expressed in the lumen of the endoplasmic reticulum (ER). However the ER membrane is impermeable to the long-chain fatty acyl-CoA substrates of these enzymes.

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  • Evaluation of the patient with jaundice. MRCP, magnetic resonance cholangiopancreatography; ALT, alanine aminotransferase; AST, aspartate aminotransferase; SMA, smooth-muscle antibody; AMA, antimitochondrial antibody; LKM, liver-kidney microsomal antibody; SPEP, serum protein electrophoresis; CMV, cytomegalovirus; EBV, Epstein-Barr virus. Isolated Elevation of Serum Bilirubin Unconjugated Hyperbilirubinemia The differential diagnosis of an isolated unconjugated hyperbilirubinemia is limited (Table 43-1).

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