As with the first edition, the primary purpose of this
book is to describe human blood group antigens and
their inheritance, the antibodies that define them, the
structure and functions of the red cell membrane
macromolecules that carry them, and the genes that
encode them or control their biosynthesis. In addition,
this book provides information on the clinical relevance
of blood groups and on the importance of blood
group antibodies in transfusion medicine in particular.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Rac1-mediated signaling plays a central role in secretion-dependent platelet aggregation in human blood stimulated by atherosclerotic plaque
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Differential expression of RANK, RANK-L, and osteoprotegerin by synovial fluid neutrophils from patients with rheumatoid arthritis and by healthy human blood neutrophils...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Detection of DNA mismatch repair proteins in fresh human blood lymphocytes - towards a novel method for hereditary non-polyposis colorectal cancer (Lynch syndrome) screening
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Effects of dexamethasone on TNF-alpha-induced release of cytokines from purified human blood eosinophils...
Chapter 17 provides knowledge of blood. This chapter presents the following content: Overview: Blood composition and functions, blood plasma, formed elements, hemostasis, transfusion and blood replacement, diagnostic blood tests, developmental aspects of blood.
Chapter 19 - The cardiovascular system: Blood vessels (part a). When you finish this chapter, you should: Describe the three layers that typically form the wall of a blood vessel, and state the function of each; define vasoconstriction and vasodilation; compare and contrast the structure and function of the three types of arteries;...
Blood, urine and stomach contents (including gastric lavage fluid and vomitus) are usually used as specimens for analysis of drugs and poisons for living subjects. A blood concentration of a toxin can be an indicator for estimation of intoxication degree. Urine sometimes contains large amounts of metabolites and/or an unchanged form of a toxin; it contains low levels of proteins, which usually interfere with analysis, and thus is suitable for screening tests using immunoassays without tedious pretreatments.
The purpose of this book remains what it was in the
first seven editions: to present the fundamental principles
and facts of human physiology in a format that
is suitable for undergraduate students, regardless of
academic backgrounds or fields of study: liberal arts,
biology, nursing, pharmacy, or other allied health professions.
Pentazocine ( Fig. 5.1) is a non-narcotic analgesic, but shows mild dependence; there are many cases of pentazocine abuse especially for medical and co-medical workers. The drug is being regulated as a subclass compound of narcotics (DEA class: IV). Pentazocine in both antemortem and postmortem specimens is being analyzed by GC [1–4], HPLC [5–7] and GC/MS . In this chapter, a simple method for GC/MS analysis of pentazocine in human whole blood and urine is presented.
⊡ Figure 5.1
Structures of pentazocine and dextromethorphan (IS).
Physics explains everything from the beginning to the end of any complete
description of the human body. Such a comprehensive discussion should begin
with the basic structure of matter, as explained by quantum mechanics – the
physics at small dimensions, and end with the mechanics of human motion,
the energetics of metabolism, the fluid dynamics of blood flow through vessels,
the mechanisms for speaking and hearing, and the optical imaging system
we call the eye.
Determination of methemoglobin (Met-Hb) in blood is important for the diagnosis of poisoning by oxidants, such as nitrite, nitrate, chlorate, chlorite, alkyl nitrites, nitroglycerin, aniline and other compounds. In 1938, Evelyn and Malloy  had devised a photoelectric method for determination of Met-Hb in blood. Minor modifications of this method were made by several researchers to increase sensitivity [2–4]. These methods are based on a phenomenon that the absorbance maximum of weakly acidic Met-Hb at 630 nm disappears by addition of cyanide.
Alcohol usually means ethanol/ethyl alcohol. It has a long history for the human being, and gives euphoric effects and sometimes improves the human relationship. In contrast, there are many cases of violence, injuries, homicides and traffic accidents with drinking; close relation can be observed between ethanol and crimes/accidents. When forensic autopsies are performed, ethanol concentrations in blood and urine are routinely measured. GC analysis of ethanol using the conventional packed columns is described in many of literature [1, 2].
As coumarin rodenticides, warfarin, coumatetralyl, coumafuryl, coumachlor and bromadiolone are commercially available in Japan. The coumarin rodenticides do not show direct anticoagulant action causing bleeding, but inhibit the metabolic cycle of vitamin K; the inhibition causes the interference with protein biosynthesis of vitamin K-dependent coagulant factors (II, VII, IX and X factors) in the liver, which are very important for the blood coagulation system. The lowered coagulant factors cause the bleeding deaths of the rodents .
Blood and urine are the common specimens for drug analysis in both antemortem and postmortem cases. Usually, urine is used for drug screening using immunoassays at the first step; secondly, the drug detected is chromatographically quantitated with blood. The data obtained are carefully assessed with taking the values reported in references into consideration together with clinical and postmortem findings; the judgement of poisoning and its degree is made comprehensively.
Pyrethroids are the general term for insecticide pyrethrins and their analogs (cinerins and jasmolins) being included in the flowers of pyrethrum or chrysanthemum. Trace concentrations of pyrethroids exert rapid toxic effects on insects, but are rapidly metabolized for detoxification in warm-blooded animals; they are insecticides with very high safety for humans. On the basis of clarification of chemical structures of the effective components of the pyrethrum, many of new synthetic pyrethroids were developed.