Xem 1-17 trên 17 kết quả Human melanoma
  • ETuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: lectroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft

    pdf10p dauphong6 05-01-2012 18 5   Download

  • Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : Electroporation increases antitumoral efficacy of the bcl-2 antisense G3139 and chemotherapy in a human melanoma xenograft

    pdf10p dauphong8 14-01-2012 17 4   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Oncolysis of malignant human melanoma tumors by Coxsackieviruses A13, A15 and A18

    pdf6p dauphong1 21-12-2011 18 2   Download

  • Lysophosphatidicacid (LPA), oneof thenaturallyoccurring phospholipids, stimulates cellmotility through theactivation of Rho family members, but the signaling mechanisms remain tobe elucidated. In thepresent study,we investigated the roles of p21-activated kinase 1 (PAK1) onLPA-induced focal adhesion kinase (FAK) phosphorylation and cell motility.

    pdf9p dell39 03-04-2013 14 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Epigenetics of human cutaneous melanoma: setting the stage for new therapeutic strategies

    pdf22p dauphong4 03-01-2012 28 8   Download

  • In chapter nineteen, Kaneda et al. develop a hemagglutinating virus of Japan envelope (HVJ-E) vector using inactivated Sendai virus, as a pseudovirion for gene and drug delivery. They evaluate the anti-tumor effects of HVJ-E itself on mouse and human melanoma in animal models, and also the enhancement of anti-tumor effects of HVJ-E containing IL-12 gene.

    pdf422p kmkmkmkmkm 08-09-2012 28 5   Download

  • Gamma-retroviral vectors, commonly designated retroviral vectors, were the first viral vector employed in Gene Therapy clinical trials in 1990 and are still one of the most used. More recently, the interest in lentiviral vectors, derived from complex retroviruses such as the human immunodeficiency virus (HIV), has been growing due to their ability to transduce non-dividing cells (Lewis et al. 1992; Naldini et al. 1996), an attribute that distinguishes them from other viral vectors, including their simple counterparts, gammaretroviral vectors.

    pdf426p kmkmkmkmkm 08-09-2012 21 4   Download

  • Modern communication tools such as the Internet provide a relatively inexpensive, accessible, easy-entry means of sharing ideas, information, and pictures around the world. In a political and human rights context, in closed societies when the more established, formal news media is denied access to or does not report on specified news events, the Internet has become an alternative source of media, and sometimes a means to organize politically.

    pdf15p doiroimavanchuadc 06-02-2013 29 4   Download

  • Desmoplastic melanoma (DM) is an unusual, non-pigmented, sclerosing variant of spindle cell malignant melanoma that can range in appearance from sarcomatoid to scar-like lesion. Cytomorphologic features described on FNA include a moderate cellularity with pleomorphic spindle cells occurring singly and in small aggregates. The spindle cells exhibit plump nuclei with deep grooves and folds, coarse and clumped chromatin, and inconspicuous to multiple, prominent nucleoli, along with naked spindly nuclei. Intranuclear cytoplasmic inclusions are rare.

    pdf806p ti_du_hoang 15-08-2012 23 2   Download

  • From this list the information specialist sifted and removed any irrelevant material based on the title or abstract before passing to the researcher. All the remaining articles were then stored in a Reference Manager electronic library. Searches were updated and re-run 6–8 weeks before the stakeholder consultation, thereby ensuring that the latest relevant published evidence was included in the database. Any evidence published after this date was not included.

    pdf0p khongmuonnghe 07-01-2013 16 2   Download

  • Thea-melanocyte-stimulating hormone (aMSH) receptor (MC1R) is amajordeterminant ofmammalianskinandhair pigmentation. Binding ofaMSHtoMC1Rinhuman mel-anocytes stimulates cell proliferation and synthesis of pho-toprotective eumelanin pigments. Certain MC1Ralleles have been associated with increased riskof melanoma. This can be theoretically considered on two grounds. First, gain-of-function mutations may stimulate proliferation, thus promoting dysplastic lesions.

    pdf9p tumor12 22-04-2013 9 2   Download

  • Excessive inflammatory responses can be horribly destructive. Unsurprisingly, therefore, immune responses are dampened down and fine-tuned in a multitude of ways to minimize their damaging effects. Four articles in this issue provide examples of such immune regulation on four different levels. Wolfgang Junger (page 201) explains that cells take it upon themselves to control their behaviour to extracellular cues through autocrine feedback loops involving purinergic receptors.

    pdf0p camchuong_1 11-12-2012 19 1   Download

  • Although the psychosocial oncology literature is strong, substantial limitations and unanswered questions remain. Much of the research has focused on heterogeneous samples of patients who vary widely across disease site (e.g., melanoma vs. breast cancer), stage of progression (e.g., localized vs. metastatic), and phase of illness (e.g., initial diagnosis vs. long-term survival). The challenges patients face vary widely across these dimensions, and therefore, it is crucial for research designs to take this into consideration....

    pdf8p taisaokhongthedung 09-01-2013 20 1   Download

  • Toll-like receptors and RNA helicase family members [retinoic acid-inducible gene I (RIG-I) and melanoma differentiation associated gene-5 (MDA5)] play important roles in the induction of interferon-bas a major event in innate immune responses after virus infection. TRIF (adaptor pro-tein of Toll-like receptor 3)-mediated and Cardif (adaptor protein of RIG-I or MDA5)-mediated signaling pathways contribute rapid induction of interferon-bthrough the activation of interferon regulatory factor-3 (IRF-3)....

    pdf16p media19 04-03-2013 12 1   Download

  • A second paragraph will address Diffuse Reflectance Spectroscopy (DRS) that has been tested on phantoms mimicking melanoma. A third paragraph will talk about two techniques that have given preliminary results on potential Breslow index determination: the first one, infrared microimaging, performed on fixed and paraffin-embedded tissues (i.e. after excision of the tumour) and the second one, photoacoustic microscopy, performed in vivo on mice on which melanoma human cells were xenografted.

    pdf706p ti_du_hoang 15-08-2012 34 2   Download

  • A series of alpha-substituted 2’,5’-dihydroxychalcones bearing a cyanide, bromine, or methyl group at alpha-position were synthesized and evaluated for in vitro cytotoxicity against three cancer cell lines, including B16, murine melanoma, HCT116 (colon cancer), A431 (human epidermoid carcinoma), and HUVEC (human umbilical venous endothelial cell). The synthesized chalcones showed significant cytotoxicity against most of cell lines, with IC50 values ranging from 0.97 to 10 µg/mL.

    pdf6p uocvong04 24-09-2015 6 2   Download

  • The MeOH extract of Nam ginseng (roots and rhizomes of Dracaena angustifolia) afforded two new furostanol saponins, named namonins E and F (1 and 2), along with another four known steroidal saponins (3 - 6). Their structures were determined on basis of spectral analyses and chemical methods. All compounds were tested for their antiproliferative activity against murine colon 26-L5 carcinoma, human HT-1080 fibrosar- coma and B-16 BL6 melanoma cells. Compounds 10, 11 and 14 showed potent antiprolife- rative activity against HT-1080 fibrosarcoma cells, having IC50 values of 0.2 µM, 0.

    pdf5p uocvong04 24-09-2015 10 2   Download

Đồng bộ tài khoản