Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Bacterial flagellin elicits widespread innate immune defense mechanisms, apoptotic signaling, and a sepsis-like systemic inflammatory response in mice...
Blackleg fungi [Leptosphaeria maculans(asexual stage Phoma lingam) and
Leptosphaeria biglobosa] are devastating plant pathogens with well-estab-lished stratagems to invade crucifers, including the production of enzymes
that detoxify plant defenses such as phytoalexins.
Cathelicidins are an important family of cationic host defense peptides in
vertebrates with both antimicrobial and immunomodulatory activities.
Fowlicidin-1 and fowlicidin-2 are two newly identified chicken cathelicidins
with potent antibacterial activities. Here we report structural and func-tional characterization of the putatively mature form of the third chicken
cathelicidin, fowlicidin-3, for exploration of its therapeutic potential.
(BQ) Part 1 book "The immune system" presents the following contents: Elements of the immune system and their roles in defense, innate immunity-the immediate response to infection, the induced response to infection, antibody structure and the generation of B cell diversity, antigen recognition by T lymphocytes,...
(BQ) Part 2 book "The immune system" presents the following contents: Preventing infection at mucosal surfaces, immunological memory and vaccination, coevolution of innate and adaptive immunity, failures of the body’s defenses, transplantation of tissues and organs, disruption of healthy tissue by the adaptive immune response, cancer and its interactions with the immune system.
Agree that in consideration of and as a condition of acceptance of my participation in the Event, for
myself, my executors and administrators, hereby waive all and any claim, right or cause of action
against the Council which I or they might otherwise have, arising out of my injury or loss of any
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for other participants and members of the general...
Infectious diseases have been known for thousands of years, although accurate
information on their etiology has only been available for about a century.
In the medical teachings of Hippocrates, the cause of infections occurring frequently
in a certain locality or during a certain period (epidemics)was sought
in “changes” in the air according to the theory of miasmas. This concept, still
reflected in terms such as “swamp fever” or “malaria,” was the predominant
academic opinion until the end of the 19th century, despite the fact that the
Dutch cloth merchant A.
Collectins are a family of collagenous calcium-dependent
defense lectins in animals. Their polypeptide chains consist
of four regions: a cysteine-rich N-terminal domain,a colla-gen-like region,ana-helical coiled-coil neck domain and
a C-terminal lectin or carbohydrate-recognition domain.
These polypeptide chains form trimers that may assemble
into larger oligomers. The best studied family members are
the mannan-binding lectin,which is secreted into the blood
by the liver,and the surfactant proteins A andD,which are
secreted into the pulmonary alveolar and airway lining fluid....
We have previously shown that high density lipoprotein is
the most abundant protein in the carp plasma and dis-plays bactericidal activityin vitro. Therefore the aim of
this study was to analyze the contribution of its principal
apolipoproteins, apoA-I and apoA-II, in defense. Both
apolipoproteins were isolated by a two step procedure
involving affinity and gel filtration chromatography and
were shown to display bactericidal and/or bacteriostatic
activity in the micromolar range against Gram-positive
and Gram-negative bacteria, including some fish patho-gens. ...
Chapter 8 provides knowledge of lymphatic & immune system. The following will be discussed in this chapter: Lymphatic system, nonspecific defenses, specific defenses, induced immunity, immunity side effects.
Events following entry of bacilli: Phagocytosis of M.tuberculosis by alveolar macrophages is the firstevent in the host-pathogen relationship that decidesoutcome of infection. Within 2 to 6 wk of infection,cell-mediated immunity (CMI) develops, and thereis an influx of lymphocytes and activatedmacrophages into the lesion resulting in granulomaformation. The exponential growth of the bacilli ischecked and dead macrophages form a caseum. Thebacilli are contained in the caseous centers of thegranuloma.
The term ‘antimicrobial peptides’ refers to a large number of peptides first
characterized on the basis of their antibiotic and antifungal activities. In
addition to their role as endogenous antibiotics, antimicrobial peptides, also
called host defense peptides, participate in multiple aspects of immunity
(inflammation, wound repair, and regulation of the adaptive immune sys-tem) as well as in maintaining homeostasis.
Antigen binding to the B-cell receptor (BCR) of pre-mature B lymphocytes
induces their apoptotic cell death, but binding to the BCR of mature
B lymphocytes triggers activation and proliferation. Binding to pre-mature
B lymphocytes is thought not only to function as a mechanism to exclude
B-cell clones that possess the ability to react with self-antigen, but also to
act as a defense mechanism in auto-immune diseases.
Chapter 28 - The lymphatic and immune systems. After completing chapter 28, you will be able to: List the pathways and organs of the lymphatic system and give their locations; define lymph and tell how it is circulated in the body; define the terms infection, pathogen, and antigen; list and describe the nonspecific body defense mechanisms; explain the signs and causes of inflammation.
Chapter 28 - The lymphatic and immune systems. After completing chapter 28, you will be able to: List the pathways and organs of the lymphatic system and give their locations; define lymph and tell how it is circulated in the body; define the terms infection, pathogen, and antigen; list and describe the nonspecific body defense mechanisms; explain the signs and causes of inflammation;...
Chapter 29 - The immune system. After completing Chapter 29, you will be able to: Define the terms infection, pathogen, and antigen; list and describe the nonspecific body defense mechanisms; explain the signs and causes of inflammation; explain what is meant by specific body defenses;...
(BQ) Part 2 book "Microbiology principles and explorations" presents the following contents: Innate host defenses, basic principles of adaptive immunity and immunization, immune disorders, urogenital and sexually transmitted diseases, diseases of the respiratory system, oral and gastrointestinal diseases, diseases of the nervous system, applied microbiology,....
The innate and acquired immune responses to L. monocytogenes have been studied extensively in mice. Shortly after IV injection, most bacteria are found in Kupffer cells in the liver, with some organisms in splenic macrophages. Listeriae that survive the bactericidal activity of initially infected macrophages grow in the cytosol and spread from cell to cell. In the liver, the result is infection of hepatocytes. Neutrophils are crucial to host defense during the first 24 h of infection, while influx of activated macrophages from the bone marrow is critical subsequently.
Harrison's Internal Medicine Chapter 61. Disorders of Granulocytes and Monocytes
Disorders of Granulocytes and Monocytes: Introduction Leukocytes, the major cells comprising inflammatory and immune responses, include neutrophils, T and B lymphocytes, natural killer (NK) cells, monocytes, eosinophils, and basophils. These cells have specific functions, such as antibody production by B lymphocytes or destruction of bacteria by neutrophils, but in no single infectious disease is the exact role of the cell types completely established.