Infectious diseases continue to represent a major diagnostic and therapeutic challenge in the
critical care unit. Infectious diseases maintain their preeminence in the critical care unit setting
because of their frequency and importance in the critical unit patient population.
Since the first edition of Infectious Diseases in Critical Care Medicine, there have been newly
described infectious diseases to be considered in differential diagnosis, and new antimicrobial
agents have been added to the therapeutic armamentarium.
The epidemiology of infectious diseases is one of the great triumphs of applied
ecology. In particular, the public health importance of parasites has
lead to a large literature, exploring their impact on the population dynamics,
population genetics and evolutionary biology of human populations. An
important milestone was the Dahlem Conference on population biology of infectious
diseases, held in 1981. The resulting book (Anderson and May 1982)
lucidly summarised the contemporary state of parasite ecology and epidemiology.
Host Factors in Infection
For any infectious process to occur, the pathogen and the host must first encounter each other. Factors such as geography, environment, and behavior thus influence the likelihood of infection. Although the initial encounter between a susceptible host and a virulent organism frequently results in disease, some organisms can be harbored in the host for years before disease becomes clinically evident. For a complete view, individual patients must be considered in the context of the population to which they belong.
Harrison's Internal Medicine Chapter 113. Introduction to Infectious Diseases: Host–Pathogen Interactions
Host–Pathogen Interactions: Introduction
Despite decades of dramatic progress in their treatment and prevention, infectious diseases remain a major cause of death and debility and are responsible for worsening the living conditions of many millions of people around the world. Infections frequently challenge the physician's diagnostic skill and must be considered in the differential diagnoses of syndromes affecting every organ system.
Infectious diseases have been a problem for military personnel throughout history. The
consequences in previous conflicts have ranged from frequent illnesses disrupting daily activities
and readiness to widespread deaths. Preventive measures, early diagnosis, and treatment greatly
limit the exposures and acute illnesses of troops today in comparison with those in armies of the
past, but infections and consequent acute illnesses still occur. In addition, long-term adverse
health outcomes of some pathogens are increasingly recognized....
(BQ) Part 1 book "Hematology, immunology and infectious disease expert consult" presents the following contents: Updated information on stem cells for the neonatologist; current issues in the pathogenesis, diagnosis, and treatment of neonatal thrombocytopenia; nonhematopoietic effects of erythropoietin,... Invite you to consult.
(BQ) Part 2 book "Hematology, immunology and infectious disease expert consult" presents the following contents: Diagnosis, treatment, and considerations on vaccine mediated prevention; neonatal T cell immunity and its regulation by innate immunity and dendritic cells; probiotics for the prevention of necrotizing enterocolitis in preterm neonates; breast milk and viral infection; probiotics for the prevention of necrotizing enterocolitis in preterm neonates,... Invite you to consult.
(BQ) Part 1 book "Harrison's infectious disease" presents the following contents: Introduction to infectious diseases, fever and approach to the febrile patient, infections in organ systems, bacterial infections.
(BQ) Part 2 book "Harrison's infectious disease" presents the following contents: Viral infections, prion diseases, fungal and algal infections, protozoal and helminthic infections, laboratory values of clinical importance.
(BQ) Part 2 book "Cases in medical microbiology and infectious diseases" presentation of content: Skin and soft tissue infections, central nervous system infection, systemic infections, advanced cases.
(BQ) Part 1 book "Pathology of infectious diseases" presentation of content: Principles of infectious disease pathology - An introduction, herpes virus infections, viral hepatitis, human papillomavirus, polyomaviruses, and parvovirus infections, human immunodeficiency virus infection,... and other contents.
(BQ) Part 2 book "Pathology of infectious diseases" presentation of content: Anaerobic bacterial infections; rickettsia, ehrlichia, and anaplasma infections; tuberculosis and infections by nontuberculous mycobacteria, buruli ulcer, dematiaceous fungal infections, parasitic infections,... and other contents.
In a Global scenario, economically progressive nations have developed medical
sciences. But still it lacks precise information during the enhancement of potent drugs
to combat ailment, which is the legacy of the organisms that generate diseases. Rising
countries had long been perceived the threat, which at times, down the lane has been
the major factor for magnanimous economic disaster and human poverty. Lot of
resources was put into force by the world community to abscond the microbial fauna
and genetically inherited diseases to contain them within the safe limits.
From HIV to influenza, the battle between infectious agents and the immune system is at the heart of disease. Knowledge of how and why parasites vary to escape recognition by the immune system is central to vaccine design, the control of epidemics, and our fundamental understanding of parasite ecology and evolution. As the first comprehensive synthesis of parasite variation at the molecular, population, and evolutionary levels, this book is essential reading for students and researchers throughout biology and biomedicine....
The Forum on Emerging Infections was created by the Institute of Medicine
(IOM) in 1996 in response to a request from the Centers for Disease Control and
Prevention (CDC) and the National Institutes of Health (NIH). The purpose of
the Forum is to provide structured opportunities for leaders from government,
academia, and industry to meet and examine issues of shared concern regarding
research, prevention, detection, and management of emerging or reemerging
The Immune Response
Innate Immunity As they have co-evolved with microbes, higher organisms have developed mechanisms for recognizing and responding to microorganisms. Many of these mechanisms, referred to together as innate immunity, are evolutionarily ancient, having been conserved from insects to humans. In general, innate immune mechanisms exploit molecular patterns found specifically in pathogenic microorganisms. These "pathogen signatures" are recognized by host molecules that either directly interfere with the pathogen or initiate a response that does so.
The global community has suffered recently from newly emerged infectious diseases and from diseases once thought to be in decline. It now faces the threat of a human influenza pandemic arising from the recently emerged avian influenza H5N1 virus. The pace of global travel, migration, and commerce has increased
(BQ) Part 1 book "Pathophysiology of disease flashcards" presents the following contents: Genetic disease, disorders of the immune system, infectious diseases, neoplasia, blood disorders, nervous system disorders, diseases of the skin, pulmonary disease, cardiovascular disorders heart disease.