Isolated helically

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  • Heat transfer calculations in different aspects of engineering applications are essential to aid engineering design of heat exchanging equipment. Minimizing of computational time is a challenging task faced by researchers and users. Methodology of calculations in some application areas are incorporated in this book, such as differential analysis of heat recoveries with CFD in a tube bank, heating and ventilation of equipment and methods for analytical solution of nonlinear problems.

    pdf382p kimngan_1 05-11-2012 55 6   Download

  • Type IIa bacteriocins, which are isolated from lactic acid bacteria that are useful for food preservation, are potent antimicrobial peptides with considerable potential as therapeutic agents for gastrointestinal infections in mam-mals. They are ribosomally synthesized as precursors with an N-terminal leader, typically 18–24 amino acid residues in length, which is cleaved during export from the produ-cing cell.

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  • Two novel pore-forming peptides have been isolated from the venom of the South-African scorpion Opistophtalmus carinatus. These peptides,designated opistoporin 1 and 2, differ by only one amino acid and belong to a group of a-helical,cationic peptides. For the first time,a comparison of the primary structures ofa-helical pore-forming peptides from scorpion venom was undertaken.

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  • Recombinant, bacterially expressed apoptin protein induces apoptosis inhuman tumour cell lines but not innormal cells, mimicking the behaviour of ectopically expressed apoptin. Recombinant apoptin is isolated exclusively as a highly stablemultimeric complex of 30–40monomers, with little, if any,a-helical and b-sheet structure. Despite its apparent disorder, multimeric apoptin is biologically active. Here, we present evidence thatmost of the apoptinmoietieswithin the complex may well share a similar conformation.

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