Kidney cells

Xem 1-20 trên 75 kết quả Kidney cells
  • Polarized membrane sorting of connexin 43 (Cx43) has not been well-char-acterized. Based on the presence of a putative sorting signal, YKLV(286– 289), within its C-terminal cytoplasmic domain, we hypothesized that Cx43 is selectively expressed on the basolateral surface of Madin–Darby canine kidney (MDCK) cells in a tyrosine-dependent manner.

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  • Madin–Darby canine kidney (MDCK) cells, which do not normally express the proteoglycan (PG) serglycin, were stably transfected with cDNA for human serglycin fused to a polyhistidine tag (His-tag). Clones with differ-ent levels of serglycin mRNA expression were generated. One clone with lower and one with higher serglycin mRNA expression were selected for this study.

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  • Strategies for Stem Cell Replacement Stem cell transplantation is not a new concept and it is already part of established medical practice. Hematopoietic stem cells (HSCs) (Chap. 68) are responsible for the long-term repopulation of all blood elements in bone marrow transplant recipients. HSC transplantation is now the gold standard against which other stem cell transplantation therapies will be measured. Transplantation of differentiated cells is also a clinical reality, as donated organs (e.g., liver, kidney) and tissues (i.e.

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  • Other Organ Systems and the Future The use of stem cells in regenerative medicine has been studied for many other organ systems and cell types, including skin, eye, cartilage, bone, kidney, lung, endometrium, vascular endothelium, smooth muscle, striated muscle, and others. In fact, the potential for stem cell regeneration of damaged organs and tissues is virtually limitless. However, numerous obstacles must be overcome before stem cell therapies can become a widespread clinical reality.

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  • Tham khảo sách 'novel insights on chronic kidney disease, acute kidney injury and polycystic kidney disease', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • Until recently, surgical resection was considered the only option for treatment of kidney cancer, especially renal cell carcinoma. The disease is relatively resistant to both radiotherapy and chemotherapy, and although alternative systemic therapies such as interleukin- 2 immunotherapy and interferon have shown promise, objective response rates are still quite low. Minimally invasive therapies have piqued the interest of researchers by showing significant improvements in treatment and management of kidney cancer.

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  • Renal Cell Carcinoma Renal cell carcinomas account for 90–95% of malignant neoplasms arising from the kidney. Notable features include resistance to cytotoxic agents, infrequent responses to biologic response modifiers such as interleukin (IL) 2, and a variable clinical course for patients with metastatic disease, including anecdotal reports of spontaneous regression. Epidemiology The incidence of renal cell carcinoma continues to rise and is now nearly 51,000 cases annually in the United States, resulting in 13,000 deaths. The male to female ratio is 2:1.

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  • Renal Cell Carcinoma: Treatment Localized Tumors The standard management for stage I or II tumors and selected cases of stage III disease is radical nephrectomy. This procedure involves en bloc removal of Gerota's fascia and its contents, including the kidney, the ipsilateral adrenal gland, and adjacent hilar lymph nodes. The role of a regional lymphadenectomy is controversial. Extension into the renal vein or inferior vena cava (stage III disease) does not preclude resection even if cardiopulmonary bypass is required.

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  • The EVI1 transcriptional repressor is critical to the normal development of a variety of tissues and participates in the progression of acute myeloid leu-kaemias. The repressor domain (Rp) was used to screen an adult human kidney yeast two-hybrid library and a novel binding partner designated ubiquitously expressed transcript (UXT) was isolated.

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  • TRPP2, also called polycystin-2, the gene product ofPKD2, is a membrane protein defective in 10–15% of cases of autosomal dominant polycystic kidney disease. Mutations in PKD2 are also associated with extrarenal dis-orders, such as hepatic cystogenesis and cardiovascular abnormalities.

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  • Insulin receptor substrate (IRS) proteins comprise a family of adaptor molecules that integrate extracellular signals from insulin and other ligands to intracellular effectors such as phosphoinositide 3-kinase and mitogen-activated protein kinase. The predominant forms of IRS protein in humans, IRS1 and IRS2, are widely expressed.

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  • Despite the aberrant expression of cholinesterases in tumours, the question of their possible contribution to tumorigenesis remains unsolved. The identifica-tion in kidney of a cholinergic system has paved the way to functional studies, but details on renal cholinesterases are still lacking. To fill the gap and to determine whether cholinesterases are abnormally expressed in renal tumours, paired pieces of normal kidney and renal cell carcinomas (RCCs) were compared for cholinesterase activity and mRNA levels....

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  • Pig kidney fructose-1,6-bisphosphatase is a homotetrameric enzyme which does not contain tryptophan. In a previous report the guanidine hydrochlo-ride-induced unfolding of the enzyme has been described as a multistate process [Reyes, A. M., Ludwig, H. C., Yan˜ez, A. J., Rodriguez, P. H and Slebe, J. C.

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  • Summarizing a decade of scientific advance and therapeutic innovation, Renal Tumor offers all physicians treating kidney cancer, as well as researchers, updated information concerning the epidemiology, biology, and treatment of renal cell carcinoma. Contributors to this book are from all over the world and are experts in their individual fields.

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  • (BQ) Part 1 book "Guyton and hall physiology review" presents the following contents: The cell and general physiology; membrane physiology, nerve, and muscle; the heart; the circulation, blood cells, immunity and blood coagulation; the body fluids and kidneys.

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  • TẾ BÀO G1, GIÁ TRỊ TRONG TẦM SOÁT CÁC BỆNH LÝ CẦU THẬN (URINARY G1 CELL: VALUE IN THE SCREENING FOR GLOMERULAR DISEASE OF THE KIDNEY) GIỚI THIỆU Tiểu máu vi thể là triệu chứng lâm sàng thưòng gặp. Có rất nhiều nguyên nhân gây tiểu máu vi thể như bệnh lý cầu hoặc ống thận, sỏi niệu, u thận, u niệu quản, nhiễm trùng tiểu trên và dưới, vỡ các mao mạch thận… Tầm soát lâm sàng tiểu máu vi thể rất tốn kém, tốn thời gian, mà lại bất tiện cho bệnh nhân.

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  • There has been a case report of exaggerated pigmented granulomatous reaction to the artificial joint implant in a 72-year-old man who had undergone bilateral total hip arthroplasty, in whom, aspirate from the inguinal region was misinterpreted as metastatic melanoma from an unknown primary. Microscopically, the smears of this patient showed both intracellular and extracellular black pigment with obscured cytomorphology; although, appreciable cells were reported to be pleomorphic with prominent nucleoli. The patient had no evidence of primary cutaneous melanoma.

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  • The third section of this book is ‘Adeno-associated-virus Vector’. Chapter nine by Sun et al. introduces the adeno-associated virus (AAV) mediated β-thalassemia gene therapy. Human hematopoietic stem cells (HSCs) were obtained from β-thalassemia patients, transfected with the recombinant AAV containing β-globin gene. The transfected cells were then transplanted into Nude/SCID mice, and the long term expression of β-globin in vivo was examined. In the tenth chapter, Korecka et al. compare AAV serotypes for gene delivery to dopaminergic neurons in the substantia nigra (SN)....

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  • In India, Foot and Mouth Disease (FMD) research started in the then Imperial Bacteriological Laboratory at Mukteswar as early as in 1929. The work on the production of vaccines using cell culture technique commenced at Mukteswar in early sixties initially in goat kidney/calf kidney cell cultures and subsequently by 1971-72 with the availability of the BHK 21 cell line in monolayer cultures. With the increased demand for the FMD vaccines, the Bangalore campus of IVRI was established in 1972 with the objective of large scale production in fermenters.

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  • ATuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: dipose-Derived Mesenchymal Stem Cell Protects Kidneys against Ischemia-Reperfusion Injury through Suppressing Oxidative Stress and Inflammatory Reaction

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