Xem 1-5 trên 5 kết quả Lewis antigens
  • As with the first edition, the primary purpose of this book is to describe human blood group antigens and their inheritance, the antibodies that define them, the structure and functions of the red cell membrane macromolecules that carry them, and the genes that encode them or control their biosynthesis. In addition, this book provides information on the clinical relevance of blood groups and on the importance of blood group antibodies in transfusion medicine in particular.

    pdf571p thuytienvang_1 31-10-2012 34 7   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I

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  • We investigated the role ofb3Gal-T5, a member of the b1,3galactosyltransferase (b1,3Gal-T) family, in cancer-associated glycosylation, focusing on the expression of sialyl-Lewis a (sLe a , the epitope of CA19.9 antigen), poly N-acetyllactosamines, and sialyl-Lewis x (sLe x )antigen.A clone permanently expressing an antisense fragment of b3Gal-T5 was obtained from the human pancreas adeno-carcinoma cell line BxPC3 and characterized. Bothb1,3Gal-T activity and sLe a expression are dramatically impaired in the clone. ...

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  • Schistosomes are parasitic flatworms that infect millions of people in (sub)tropical areas around the world. Glycoconjugates of schistosomes play a critical role in the interaction of the different developmental stages of the parasite with the host. In particular, glycosylated components of the eggs produced by the adult worm pairs living in the bloodstream are strongly immunogenic.

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  • Adecrease in the level ofO-acetylatedsialicacidsobserved in colorectal carcinoma may lead to an increase in the expres-sion of sialyl Lewis X , a tumor-associated antigen, which is related toprogressionof colorectal cancer tometastasis. The underlyingmechanism for this reduction is, however, not fully understood. Two enzymes are thought to be primarily responsible for the turnover of O-acetyl ester groups on sialic acids; sialate-O-acetyltransferase (OAT) and sialate-O-acetylesterase (OAE).

    pdf10p dell39 03-04-2013 24 2   Download

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