Physical chemistry of macromolecules is a course that is frequently offered in the
biochemistry curriculum of a college or university. Occasionally, it is also offered in
the chemistry curriculum. When it is offered in the biochemistry curriculum, the
subject matter is usually limited to biological topics and is identical to biophysical
chemistry. When it is offered in the chemistry curriculum, the subject matter is
often centered around synthetic polymers and the course is identical to physical
Chapter 5 - The structure and function of macromolecules. In this chapter, you should be able to: List and describe the four major classes of organic molecules; explain: monomers, polymers, dehydration synthesis with the type of covalent bond for each; distinguish between monosaccharides, disaccharides, and polysaccharides.
1928, Frederick Griffith, was one of the first experiments
suggesting that bacteria are capable of transferring
genetic information through a process known
§ 1944:Avery, MacLeod & McCarty - Strong evidence that
DNA is genetic material
§ 1950:Chargaff - careful analysis of DNA from a wide
variety of organisms.
As with the first edition, the primary purpose of this
book is to describe human blood group antigens and
their inheritance, the antibodies that define them, the
structure and functions of the red cell membrane
macromolecules that carry them, and the genes that
encode them or control their biosynthesis. In addition,
this book provides information on the clinical relevance
of blood groups and on the importance of blood
group antibodies in transfusion medicine in particular.
The expression of proteoglycans (PGs), essential macromolecules of the
tumor microenvironment, is markedly altered during malignant transforma-tion and tumor progression. Synthesis of stromal PGs is affected by factors
secreted by cancer cells and the unique tumor-modified extracellular matrix
may either facilitate or counteract the growth of solid tumors.
The molecular masses of macromolecules and subunits of the extracellular
hemoglobin from the fresh-water crustaceanDaphnia magnawere deter-mined by analytical ultracentrifugation, multiangle laser light scattering
and electrospray ionization mass spectrometry.
International Tables for Crystallography, Volume F, Crystal-
lography of Biological Macromolecules, was commissioned by
the International Union of Crystallography (IUCr) in recognition
of the extraordinary contributions that knowledge of macro-
molecular structure has made, and will make, to the analysis of
biological systems, from enzyme catalysis to the workings of a
Chapter 3 - Macromolecules and the origin of life. In this chapter, students will be able to understand: What kinds of molecules characterize living things? What are the chemical structures and functions of proteins? What are the chemical structures and functions of carbohydrates? What are the chemical structures and functions of lipids? What are the chemical structures and functions of nucleic acids? How did life on earth begin?
(BQ) Part 2 book "Harper’s illustrated biochemistry" presents the following contents: Structure, function and replication of informational macromolecules; biochemistry of extracellular and intracellular communication, special topics.
Ebook Handbook of polymer synthesis the book analyzes biodegradable polymers for biomedical applications; Investigates the use of polyolefins, polymeric dienes, aromatic polyethers, polymides, and metal-containing macromolecules; and covers polymers of Acrylic Acid, Methacrylic Acid, and Maleic Acid.
Một axít nucleic là một đại phân tử sinh học có phân tử lượng lớn (tiếng Anh: high-molecular-weight biochemichal macromolecule) được cấu tạo từ các chuỗi nucleotide nhằm truyền tải thông tin di truyền (genetic information). Hai loại axít nucleic phổ biến nhất là deoxyribonucleic acid (ADN) và ribonucleic acid (ARN). Axít nucleic có mặt ở hầu hết các tế bào sống và virút.
Smart polymers are macromolecules capable of undergoing rapid, reversible
phase transitions from a hydrophilic to a hydrophobic microstructure. These
transitions are triggered by small shifts in the local environment, such as
slight variations in temperature, pH, ionic strength, or the concentration of
specific substances like sugars.
Smart polymers have an extensive range of applications, but this book
focuses solely on their roles within the fields of bioseparation and biomedicine.
Until recently, polymers were considered to be passive participants
within these fields.
Biomimetics is the science of emulating nature’s design. In nature, living organisms
synthesize mineralized tissues and this process of biomineralization is under strict biological
control. It involves the interactions of several biological macromolecules among
themselves and with the mineral components. Generally, natures design principles are
based on a “Bott om-Up” strategy. Such processes lead to the formation of hierarchically
structured organic-inorganic composites with mechanical properties optimized for a
Một axít nucleic là một đại phân tử sinh học có phân tử lượng lớn (tiếng Anh: high-molecular-weight biochemichal macromolecule) được cấu tạo từ các chuỗi nucleotide nhằm truyền tải thông tin di truyền (genetic information).
A need for a book on immunology which primarily focuses on the needs of medical
and clinical research students was recognized. This book is relatively short and
contains topics considered relevant to the understanding of human immune system
and its role in health and diseases. Immunology is the study of our protection from
foreign macromolecules or invading organisms and our responses to them. These
invaders include viruses, bacteria, protozoa or even larger parasites.
Bioinformatics is an emerging and rapidly growing area of science. Not sur-
prisingly, there is tremendous lag time between the state of knowledge and
the publication of manuals for those who need to fathom the basic knowledge
and apply it in problem solving. Mr. Rashidi and Dr. Buehler have found a
way to address these needs. Their book provides excellent, timely, and easy-
to-understand information and advice for those without a great...
Proteins are the driving force for all cellular processes. They regulate several cellular
events through binding to different partners in the cell. They are capable of binding to
other proteins, peptides, DNA, and also RNA. These interactions are essential in the
regulation of cell fates and could be important in drugs development. For example
RNA interacting proteins regulate gene expression through the binding to different
mRNAs. These mRNAs could be involved in important cellular processes such as cell
survival or apoptosis.
- Polysaccharides are macromolecules, polymers with a few hundred to a few thousand monosaccharides joined by glycosidic linkages.
- Some polysaccharides serve as storage material, hydrolyzed as needed to provide sugar for cells.
- Other polysaccharides serve as building material for structures that protect the cell or the whole organism.
- The architecture and function of a polysaccharide are determined by its sugar monomers and by the positions of its glycosidic linkages.
Vitamin E is an important topic because many benefits and some risks have
been attributed to it when used as a nutritional supplement. Moreover, there
has been considerable progress in the basic science of this vitamin in recent
years. This volume reviews recent aspects of the biochemistry and molecular
biology of this vitamin, associated macromolecules, metabolism of the
vitamin and its derivatives, and its many roles in health and disease. The
various contributions comprising this volume are listed here in the order in
which they are presented in the volume....
The extracellular matrix (ECM) represents a complex organization of macromolecules
that surrounds the cell and comprises the substratum onto which the cell
may be attached. The properties and functions of the ECM depend ultimately on
its structure, molecular components, architecture, and dynamic modulation.
Because the critical role of ECM involved in cell biology and physiology has long
been recognized, the structure and biology of the ECM have been extensively
studied (Yurchenco and Birk 1994 ; Ayad et al. 1998 ; Robert 2001 ) .