Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Psychosocial stress, demoralization and the consumption of tobacco, alcohol and medical drugs by veterinarians
Prescription and over-the-counter drugs help millions of people with devastat-ing diseases and chronic conditions. But in the process, these medications can also deplete the body’s natural stores of vitamins, minerals, and hormones—the very nutrients you need to keep energy levels high, fend off infections, and be healthy. Pharmacist Suzy Cohen calls these medications “drug muggers,” and she says it’s essential to replenish what a drug mugger steals from your body in order to feel your best and avoid side effects.
The brain is a physical organ just like the heart or lungs or liver and, as such, its functioning can be
affected by our environment, particularly the substances we put in our bodies. I first became aware of
smart drugs from an article in Omni magazine some twenty years ago while I was attending college.
It was also at that time that I was becoming aware of health foods, and the article so impressed me
that, while other students were taking speed and No-Doz to cram for exams, I was gobbling hand-fuls
of vitamins. While my approach was undoubtedly too haphazard and belated to have...
Our main purpose in editing this book is to provide the health care practitioner
with general clinical practical guidelines regarding the use of pediatric
cardiovascular drugs. We also intend to provide an overview of basic pediatric
cardiovascular principles. We realize the need for a pocket reference handbook that
is tailored to meet the daily challenges of practitioners that care for pediatric
Forensic autopsy is an important task for proving crimes medically; unfortunately, every department of legal medicine of Japanese universities is suffering from insufficient staffs and budget. About 30 years ago, one of the authors started the analysis of drugs and poisons at the Department of Legal Medicine, Hiroshima University School of Medicine. At that time, the author did not have much knowledge about poison analysis; but it is a good memory that many good friends of toxicological societies gave the author many useful suggestions on analytical methods.
Pentazocine ( Fig. 5.1) is a non-narcotic analgesic, but shows mild dependence; there are many cases of pentazocine abuse especially for medical and co-medical workers. The drug is being regulated as a subclass compound of narcotics (DEA class: IV). Pentazocine in both antemortem and postmortem specimens is being analyzed by GC [1–4], HPLC [5–7] and GC/MS . In this chapter, a simple method for GC/MS analysis of pentazocine in human whole blood and urine is presented.
⊡ Figure 5.1
Structures of pentazocine and dextromethorphan (IS).
Current Medical Diagnosis & Treatment 2007 is the 46th annual volume of this single-source
reference for practitioners in both hospital and ambulatory settings. It emphasizes the practical
features of clinical diagnosis and patient management in all fields of internal medicine and in
specialties of interest to primary care practitioners and subspecialists who provide generalist care.
We are pleased to present the 7th edition of the Clinician’s Pocket Drug Reference.
This book is based on the drug presentation style used since 1983 in the Clinician’s
Pocket Reference, popularly known as the Scut Monkey Book. Our goal is to identify
the most frequently used and clinically important medications, including
branded, generic and OTC products. The book includes well over 1000 medications
and is designed to represent a cross section of commonly used products in
medical practices across the country....
The Tenth Edition of the Handbook of Clinical Drug Data continues a long
tradition of providing clinically relevant, well-referenced drug information compiled
by expert clinicians and presented in a compact format. The formats of all
sections should be familiar to users of the ninth edition. As with recent editions,
information in the Handbook is divided into three part
The art of compliance is a craft much like that of a carpenter who learns to
work with various kinds of wood and designs. Ours is an industry wrought
with differences. While the regulations that govern FDA-regulated industries
are proscribed, how the regulations are interpreted and applied really
depends on experience and how well one has mastered the craft of compliance.
There are no proscribed procedures, but there are guideposts common
to all FDA-regulated industries, whether a firm manufactures medical
devices, pharmaceuticals, or biological products....
Th e readers of this book will immediately realize that all authors are Japanese scientists; this is
the English translation of a book which was published in Japanese by Jiho, Inc., Tokyo in 2002.
Upon translation, the Editors added fi ve new chapters to the previous 67 chapters in view of
international occurences of poisoning by drugs and poisons.
Th e most important aim of this book is to provide the most reliable and reproducible methods
for analysis of drugs and poisons; therefore, the newest methods and ones requiring
skills have not been adopted.
The field of drug therapy is a rapidly changing and somewhat bewildering area to study. In
developing and writing this textbook, we consulted the most up-to-date sources for information
on new drug therapies. No textbook can be complete, especially when it covers an area as vast as
the field of ocular pharmacology and therapeutics. Nonetheless, we have made a conscientious
effort to cover the most important and commonly used medications in a format that is easy to
The impetus to provide a seventh edition of Cardiac Drug Therapy was generated by
the positive comments received from readers worldwide, and from favorable reviews of
earlier editions. The seventh edition updates and revises the sixth edition in several
respects. In particular, the text includes: Six new chapters that deal with ongoing important
controversies regarding the use of several widely used cardiac drugs.
Controversies have arisen regarding the use of beta blockers for the treatment of
β-Lactum antibiotics constitute an important class of antibacterial agents being used extensively for both humans and food-producing animals to treat or prevent infections. The drugs occasionally cause human deaths due to anaphylactic shock during medical treatments, especially when they are parenterally administered without their prior intracutaneous tests. These cases are usually handled as medical accidents (malpractice), and subjected to autopsies and analysis of the drugs used. These antibiotics are composed of cephems ( Table 10.1) and penicillins ( Table 10.
Delayed hypersensitivity mechanisms directed by drug-specific T cells are probably the most important mechanisms in the etiology of the most common drug eruptions—morbilliform exanthems—and also of rare and severe forms such as hypersensitivity syndrome, acute generalized exanthematous pustulosis (AGEP), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN). Drugspecific T cells have been detected in these types of drug eruptions.
Contrary to what has been believed for years, the antigen is more often the native drug itself than its metabolites.
Untoward cutaneous responses to drugs can arise as a result of immunologic or nonimmunologic mechanisms. A variety of adverse reactions result from mechanisms that do not involve an immunologic process. Drug reactions are a public health problem because of their frequent occurrence, occasional severity, and impact on the use of medications. The skin is among the organs most often affected by adverse drug reactions. The list of conditions that can be triggered by medications includes nearly all dermatologic diseases.
The development of drug treatments for diseases of the retina and back of the eye has
been slow. Among the principal causes for this have been a failure of the pharmaceutical
industry to appreciate the potential size of the market these diseases represent,
a poor understanding of the disease processes themselves, and technical
difficulty in delivering drugs to the back of the eye. There have been recent rapid
advances in all three areas with many more changes likely to occur in the next decade.
PARKSERVICE is a new telemedical application combining home-based support for
people with Parkinson’s disease (PD) and a PD-specific walking aid which uses a
strategy known as visual cueing. PD is estimated to affect 100-180 per 100,000 of the
population (with most surveys favoring the higher estimate) and has an annual
incidence of 4-20 per 100,000,. Taking a population of approximately 450M
citizens this implies 450,000-900,000 people with PD (PWP) in the EU.
The basic precepts underlying previous editions of Clinical Drug Therapy continue to guide the
writing of this seventh edition. The overall purpose is to promote safe, effective, and rational drug
• Providing information that accurately reflects current practices in drug therapy.
• Facilitating the acquisition, comprehension, and application of knowledge related to drug
therapy. Application requires knowledge about the drug and the client receiving it.