Xem 1-20 trên 75 kết quả Metazoan systems
  • From the beginnings of modern science, lakes have fulfilled a focus of attention. Doubtless, this has something to do with the lure that water bodies hold for most of us, as well as for long having been a source of food as well as water. Authors, from Aristotle to Izaak Walton, committed much common knowledge of the freshwater fauna to the formal written record, so it is still a little surprising to realise that the formal study of lakes—limnology (from the Greek word, limnos, a lake)—is scarcely more than a century in age (Forel 1895).

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  • “Dunsel … is a term used by midshipmen at Starfleet Academy. It refers to a part which serves no useful purpose.” Mr Spock, in Star Trek, Episode 53: “The Ultimate Computer” Paranoia began morphing into depression with the arrival of the 15 January 2004 issue of Nature. On page 247 was a paper by King et al. entitled ‘Functional genomic hypothesis generation and experimentation by a robot scientist’. The paper describes an automated system that uses techniques from artificial intelligence to formulate hypotheses to explain observations.

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  • Aidan Budd*, Stephanie Blandin*, Elena A Levashina† and Toby J Gibson* Addresses: *European Molecular Biology Laboratory, 69012 Heidelberg, Germany. †UPR 9022 du CNRS, IBMC, rue René Descartes, F-67087 Strasbourg CEDEX, France. Correspondence: Toby J Gibson. E-mail: toby.gibson@embl.de reviews Published: 26 May 2004 Genome Biology 2004, 5:R38 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/6/R38 Received: 20 February 2004 Revised: 2 April 2004 Accepted: 8 April 2004 © 2004 Budd et al.

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  • Department of Biochemistry and Molecular Biology and †The Genes and Development Graduate Program, The University of Texas M. D. Anderson Cancer Center, and ‡Program in Developmental Biology, Baylor College of Medicine, Houston, TX 77030, USA. Correspondence: Georg Halder. E-mail: ghalder@mdanderson.org comment reviews Published: 25 March 2004 Genome Biology 2004, 5:216 The electronic version of this article is the complete one and can be found online at http://genomebiology.

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  • A study to measure indoor concentrations and emission rates of volatile organic compounds (VOCs), including formaldehyde, was conducted in a new, unoccupied manufactured house installed at the National Institute of Standards and Technology (NIST) campus. The house was instrumented to continuously monitor indoor temperature and relative humidity, heating and air conditioning system operation, and outdoor weather. It also was equipped with an automated tracer gas injection and detection system to estimate air change rates every 2 h.

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  • A report on the Molecular Approaches to Malaria meeting, Lorne, Australia, 4-8 February 2004. species-specific genes are mainly involved in unique, species-specific processes of the parasites and thus are potential targets for antimalarial strategies. David Roos (University of Pennsylvania, Philadelphia, USA) introduced the updated version of the Plasmodium Genome Resource [http://www.PlasmoDB.org], which includes the complete P. falciparum genome as well as the partial genome sequences of additional plasmodial...

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  • Using the broadest possible definition, a lipid (Greek lipos = fat ) may be defined as a compound of low or intermediate molecular weight (5000), a substantial proportion of which is made up of hydrocarbons. Included are diverse compounds such as fatty acids; soaps; detergents; steroids; mono-, di-, and triacylglycerols; and more complex compounds such as phospholipids, sphingolipids, glycolipids, and lipopolysaccharides.

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  • The EU needs to protect its citizens and their rights from threats and challenges and further remove obstacles to circulation of citizens in Europe. This includes fighting crime and corruption, controlling our external borders and ensuring the respect of the rule of law and of fundamental rights, with the right balance between security and mobility. It also needs a well functioning and efficient justice system to support growth, entrepreneurship and attract investors.

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  • Collection of reports on forestry research is published in the journal International Forestry topics: Ecological aspects of the floral phenology of the cork-oak (Q suber L): why the Annual and Biennial biotypes appear?

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  • Many drugs have unknown, controversial or multiple mechanisms of action. Four recent ‘chemical genomic’ studies, using genome-scale collections of yeast gene deletions that were either arrayed or barcoded, have presented complementary approaches to identifying gene-drug and pathwaydrug interactions. deposited research The fact that much of modern drug research is target-oriented obscures the long history during which the effects of drugs were discovered prior to identification of their targets. There remain many...

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  • The Basel Committee on Banking Supervision, after an extensive consultation process, redrafted its recommendations for credit institutions’ regulatory capital requirements (Basel I) issued in 1988. The revision was motivated by the wish to adequately refl ect current developments in banking and to strengthen the stability of the international fi nancial system.

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  • The SAS In-Database technology described in this paper relates to a variety of environments, including grid, blade servers, and event management containers. The focus here is on its application to database management systems. The goal of the SAS In-Database initiative is not only to achieve deeper technical integration with database providers, but to also extend this integration to a unique and differentiated value proposition that blends the best SAS data integration and analytics with the core strengths of databases.

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  • Cyclooxygenases (COXs) catalyze the rate-limiting step in the production of prostaglandins, bioactive compounds involved in processes such as fever and sensitivity to pain, and are the target of aspirin-like drugs. COX genes have been cloned from coral, tunicates and vertebrates, and in all the phyla where they are found, there are two genes encoding two COX isoenzymes; it is unclear whether these genes arose from an early single duplication event or from multiple independent duplications in evolution. The...

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  • This information has not been peer-reviewed. Responsibility for the findings rests solely with the author(s). comment Deposited research article Gene expression profiles of peripheral blood cells in type 2 diabetes and nephropathy in Asian Indians Paturi V Rao*, Xinfang Lu†, Patrick Pattee†, Mark Turner†, Nandgaonkar Suguna* and Srinivasa R Nagalla† Addresses: *Department of Endocrinology and Metabolism, Nizam's Institute of Medical Sciences, Hyderabad 500 082, India.

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  • Prediction of Saccharomyces cerevisiae replication origins Adam M Breier*, Sourav Chatterji† and Nicholas R Cozzarelli‡ Addresses: *Graduate Group in Biophysics, University of California-Berkeley, Berkeley, CA 94720-3204, USA. †Department of Computer Science, University of California-Berkeley, Berkeley, CA 94720-3204, USA. ‡Department of Molecular and Cellular Biology, Barker Hall, University of California-Berkeley, Berkeley, CA 94720-3204, USA. Correspondence: Nicholas R Cozzarelli. E-mail: ncozzare@socrates.berkeley.

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  • Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA. †Department of Biology, University of New Mexico, Albuquerque, NM 87131, USA. ‡Current address: DOE Joint Genome Institute, 2800 Mitchell Drive, Bldg 400, Walnut Creek, CA 94596, USA. Correspondence: Stephanie W Ruby. E-mail: sruby@unm.edu reviews Published: 30 March 2004 Genome Biology 2004, 5:R29 The electronic version of this article is the complete one and can be found online at http://genomebiology.

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  • 30 April 2004 Genome Biology 2004, 5:324 The electronic version of this article is the complete one and can be found online at http://genomebiology.com/2004/5/5/324 © 2004 BioMed Central Ltd reviews A report on the 5th annual Advances in Genome Biology and Technology (AGBT) and Automation in DNA Mapping and Sequencing (AMS) meeting, Marco Island, USA, 4-7 February 2004.

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  • The AICPA Government Performance and Accountability Committee (GPAC) represents CPAs working in all levels of federal, state and local government. It also serves the public who depend on CPAs to help ensure government accountability.

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  • Though systems still exist based on these models, they are not nearly as common as they once were. A directory service like ActiveDirectory orOpenLDAP is where you are most likely to engage in new hierarchical development. Another model—the object model—is slowly coming into favor for limited problem domains. As its name implies, it is a data model based on object-oriented concepts. Because Java is an object-oriented programming language, it actually maps best to the object model.

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