This comprehensive volume covers the major viral, bacterial and fungal diseases in fi n- and
shellfi shes. It completes the three-volume series on fi sh diseases and disorders; Volume I
(published in 1995) is on parasitic diseases in fi n- and shellfi shes while Volume II (published
in 1998) deals with non-infectious disorders in fi nfi sh. Reviews in the three volumes
are written by international authorities that are actively working in the area or have contributed
greatly to our understanding of specifi c piscine diseases or disorders.
(BQ) Part 2 book "Microbiology with diseases by body system" presents the following contents: Innate immunity, adaptive immunity, immunization and immune testing, microbial disease of the skin and wounds, applied and environmental microbiology, applied and environmental microbiology,....
(BQ) Part 2 book "Prescott's microbiology" presentation of content: The diversity of the microbial world, ecology and symbiosis, pathogenicity and host response, microbial diseases, detection, and their control, applied microbiology,...and other contents.
As for the fi rst edition of this volume, the chapters comprise comprehensive discussions of
the some of the major non-infectious disorders of fi nfi sh. It is the second volume of a threevolume
series on fi sh diseases and disorders; Volume 1 deals with parasitic diseases and
Volume 3 with microbial diseases. Reviews in the three volumes are written by leading
international authorities who are actively working in the area or who have contributed
greatly to our understanding of specifi c diseases or disorders....
In a Global scenario, economically progressive nations have developed medical
sciences. But still it lacks precise information during the enhancement of potent drugs
to combat ailment, which is the legacy of the organisms that generate diseases. Rising
countries had long been perceived the threat, which at times, down the lane has been
the major factor for magnanimous economic disaster and human poverty. Lot of
resources was put into force by the world community to abscond the microbial fauna
and genetically inherited diseases to contain them within the safe limits.
Harrison's Internal Medicine Chapter 114. Molecular Mechanisms of Microbial Pathogenesis
Molecular Mechanisms of Microbial Pathogenesis: Introduction
Over the past three decades, molecular studies of the pathogenesis of microorganisms have yielded an explosion of information about the various microbial and host molecules that contribute to the processes of infection and disease.
Encounters with Epithelial Cells
Over the past decade, many bacterial pathogens have been shown to enter epithelial cells (Fig. 114-2); the bacteria often use specialized surface structures that bind to receptors, with consequent internalization. However, the exact role and the importance of this process in infection and disease are not well defined for most of these pathogens. Bacterial entry into host epithelial cells is seen as a means for dissemination to adjacent or deeper tissues or as a route to sanctuary to avoid ingestion and killing by professional phagocytes.
Encounters with Phagocytes
Phagocytosis and Inflammation Phagocytosis of microbes is a major innate host defense that limits the growth and spread of pathogens. Phagocytes appear rapidly at sites of infection in conjunction with the initiation of inflammation. Ingestion of microbes by both tissue-fixed macrophages and migrating phagocytes probably accounts for the limited ability of most microbial agents to cause disease.
Many diseases are caused primarily by pathogens growing in tissue sites that are normally sterile. Pneumococcal pneumonia is mostly attributable to the growth of S. pneumoniae in the lung and the attendant host inflammatory response, although specific factors that enhance this process (e.g., pneumolysin) may be responsible for some of the pathogenic potential of the pneumococcus. Disease that follows bacteremia and invasion of the meninges by meningitisproducing bacteria such as N. meningitidis, H. influenzae, E.
Transmission to New Hosts
As part of the pathogenic process, most microbes are shed from the host, often in a form infectious for susceptible individuals. However, the rate of transmissibility may not necessarily be high, even if the disease is severe in the infected individual, as transmissibility and virulence are not linked traits.
(BQ) Part 2 book "Microbiology - An introduction" presentation of content: Principles of disease and epidemiology, microbial mechanisms of pathogenicity, practical applications of immunology, antimicrobial drugs, microbial diseases of the skin and eyes, microbial diseases of the skin and eyes, microbial diseases of the skin and eyes, applied and industrial microbiology,...
(BQ) Part 1 book "Microbiology with diseases by body system" presents the following contents: A brief history of microbiology, the chemistry of microbiology, cell structure and function, microbial genetics, microbial metabolism, characterizing and classifying prokaryotes,... and other contents.
Pest and disease management continues to be an important challenge to the
agricultural community. Confronted with the shifts in pest pressure and the rise in
new pest and crop problems, coupled with public concern over pesticide use and
more stringent environmental regulations, today’s crop producer must exhibit good
stewardship and stay current with new technologies in order to produce high-quality
crops in a profitable manner.
A well-developed knowledge of clinical microbiology is critical for the practicing physician in any medical field. Bacteria, viruses, and protozoans have no respect for the distinction between ophthalmology, pediatrics, trauma surgery, or geriatric medicine. As a physician you will be faced daily with the concepts of microbial disease and antimicrobial therapy.
Bacteria are non-chlorophyllated unicellular organisms that reproduce by fission and do not
present nuclear envelope. Gram´s stain is a staining technique used to classify bacteria based
on the different characteristic of their cell walls. Gram-positive or Gram-negative bacteria
are determined by the amount and location of peptidoglycan in the cell wall, exhibiting
different chemical compositions and structures, cell-wall permeabilities, physiologies,
metabolisms, and pathogenicities.
Resistance towards the responsible pathogens are also seen in developed countries. The
situation has worsened often due to limited resource available to investigate and provide
reliable susceptibility data on which rational treatments can be based as well as means to
optimize the use of antimicrobial agents. The emergence of multi-drug-resistant isolates in
tuberculosis, acute respiratory infections and diarrhea, often referred to as diseases of
poverty, has had its greatest toll in developing countries.
Malaria, caused by four species of Plasmodium, of which Plasmodium falciparum is the most
dangerous, remains the world's most devastating human parasitic infection. This chapter deals with
the properties and uses of important drugs used to treat and prevent this infection. Highly effective
agents that act against asexual erythrocytic stages of malarial parasites responsible for clinical
attacks include chloroquine, quinine, quinidine, mefloquine, atovaquone, and the artemisinin
Infertility is a disease of the reproductive system that impairs one of the
body's most basic functions: the conception of children. In the United States,
infertility affects about 7.3 million women and their partners, or about 12%
of the reproductive-aged population. For many of these couples, the answer
lies in conventional medical therapy, such as drug treatment or surgery to
repair reproductive organs. Since 1978, ART has provided another solution
for many would-be parents.
Sarcoidosis is one of the best-known systemic granulomatous diseases. Despite intensive
investigation, however, the etiology of sarcoidosis has remained unresolved for more than 100
years . Sarcoidosis seems to result from the exposure of a genetically susceptible subject to
an environmental agent, and microbial etiologies of sarcoidosis have long been considered
based on the clinical similarities to infectious granulomatous diseases .