MicroRNAs (miRNAs) have been proven to play important roles at the
post-transcriptional level in animals and plants. To investigate clustering
patterns and specific sequence characteristics in the flanking regions of
plant miRNA genes, we performed genome-wide analyses ofArabidopsis
thaliana, Populus trichocarpa, Oryza sativaand Sorghum bicolor.
Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí y học Molecular Biology cung cấp cho các bạn kiến thức về ngành sinh học đề tài: Learning from positive examples when the negative class is undetermined- microRNA gene identification...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Regulatory conservation of protein coding and microRNA genes in vertebrates: lessons from the opossum genome...
Conservation of microRNAs (miRNAs) among species suggests that they
bear conserved biological functions. However, sequencing of new miRNAs
has not always been accompanied by a search for orthologues in other spe-cies. I report herein the results of a systematic search for interspecies ortho-logues of miRNA precursors, leading to the identification of 35 human and
45 mouse new putative miRNA genes. MicroRNA tracks were written to
visualize miRNAs in human and mouse genomes on the UCSC Genome
Our understanding of the importance of noncoding RNA molecules is steadily growing. One such important
class of RNA molecules are microRNAs (miRNAs). These tiny RNAs fulfi ll important functions in cellular
behavior by infl uencing the protein output levels of a high variety of genes through the regulation of
target messenger RNAs. Moreover, miRNAs have been implicated in a wide range of diseases. In pathological
conditions, the miRNA expression levels can be altered due to changes in the transcriptional or
posttranscriptional regulation of miRNA expression.
MicroRNAs (miRNAs) comprise species of short noncoding RNA that
regulate gene expression post-transcriptionally. Recent studies have demon-strated that epigenetic mechanisms, including DNA methylation and his-tone modification, not only regulate the expression of protein-encoding
genes, but also miRNAs, such as let-7a, miR-9, miR-34a, miR-124, miR-137, miR-148 and miR-203.
MicroRNAs (miRNAs) are a class of small noncoding RNAs that have
gained status as important regulators of gene expression. Recent studies
have demonstrated that miRNAs are aberrantly expressed in the cardiovas-cular system under some pathological conditions.
The discovery that microRNAs (miRNAs) are synthesized as hairpin-con-taining precursors and share many features has stimulated the development
of several computational approaches for identifying new miRNA genes in
various animal species.
RNomics is a newly emerging sub-discipline of genomics that categorically
studies the structure, function and processes of non-coding ribo nucleic acids in
a cell. MicroRNomics is a sub-field of RNomics that describes the biogenesis and
mechanisms of tiny RNA regulators, and their involvement in the processes of
development, differentiation, cell proliferation, cell death, chromosomal segregation
and metabolism. The discovery of microRNAs in species ranging from
Caenorhabditis elegans (C.
MicroRNAs (miRNAs) are small noncoding RNAs (~22 nucleotides) that regulate gene expression by cleaving mRNAs or inhibiting translation. The baboon is a well-characterized cardiovascular disease model; however, no baboon miRNAs have been identified. Evidence indicates that the baboon and human genomes are highly conserved; based on this conservation, we hypothesized that comparative genomic methods could be used to identify baboon miRNAs.
Non coding endogenous RNAs were first discovered in the last decade of the previous
century. These new discoveries changed our views of the transcriptome landscape of
plant genomes and paradigms of the regulation of gene expression. With the beginning
of this century, we have witnessed an explosion of studies on small regulatory
RNAs that has yielded a basic understanding of the many types of small RNAs in
diverse eukaryotic species and how they are functioning as RNA–protein complexes
along the RNA silencing pathways.
important regulators of biological processes in animals
and plants. MiRNAs regulate gene expression at
the posttranscriptional level by binding to mRNAs and
either inhibit translation or modify the stability of the
mRNA. Due to the important biological role of miRNAs
it is of great interest to study their expression level in
the cells. Furthermore, miRNAs have been associated
with cancer and other diseases  and miRNA expression
can help in the diagnosis and prognostic of human
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài:The roles of binding site arrangement and combinatorial targeting in microRNA repression of gene expression...
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines
Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Gene and microRNA analysis of neutrophils from patients with polycythemia vera and essential thrombocytosis: down-regulation of micro RNA-1 and -133a
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Research Article MicroRNA Target Detection and Analysis for Genes Related to Breast Cancer Using MDLcompress
MicroRNAs are a class of small noncoding RNAs that function as key reg-ulators of gene expression at the post-transcriptional level. Recently, micr-oRNA-373 (miR-373) has been found to function as an oncogene in
testicular germ cell tumors.
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: cGlobal analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Minireview cung cấp cho các bạn kiến thức về ngành y đề tài: Preferential regulation of duplicated genes by microRNAs in mammals...