Xem 1-20 trên 212 kết quả Molecular approaches
  • A report on the Molecular Approaches to Malaria meeting, Lorne, Australia, 4-8 February 2004. species-specific genes are mainly involved in unique, species-specific processes of the parasites and thus are potential targets for antimalarial strategies. David Roos (University of Pennsylvania, Philadelphia, USA) introduced the updated version of the Plasmodium Genome Resource [http://www.PlasmoDB.org], which includes the complete P. falciparum genome as well as the partial genome sequences of additional plasmodial...

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Molecular approaches to the analysis of deformed wing virus replication and pathogenesis in the honey bee, Apis mellifera

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Report on the Molecular Approaches to Osteoarthritis Symposium, Imperial College London, UK, 18–20 April 2004...

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  • Lung cancer is the leading cause of cancer death among men and women in the United States with 170,000 deaths per year. This exceeds the sum of the next three leading causes of death due to cancer: breast, colon, and prostate. There are over 1 million deaths worldwide due to lung cancer, making it truly an epidemic. Fewer than 15% achieve a 5-yr survival. The vast majority (85%) present with advanced disease, although stage I patients may have a 5-yr survival approaching 70% (1).

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  • Next, a few words about our strategy. It is well recognized now that one has to go beyond the Einstein-Hilbert action for gravity, both from the experimental viewpoint (eg.,because of Dark Energy) and from the theoretical viewpoint (eg., because of the UV incompleteness of quantized Einstein gravity, and the need of its unification with the Standard Model of Elementary Particles). In our approach, the origin of inflation is purely geometrical, ie. is closely related to space-time and gravity.

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  • Lung cancer is the most frequent cause of cancer deaths in both men and women in the U.S. (1). Although tobacco smoking is accepted as the number one cause of this devastating disease, our understanding of the acquired genetic changes leading to lung cancer is still rudimentary. Lung cancer is classifi ed into two major clinic-pathological groups, small cell lung carcinoma (SCLC) and non-small cell lung carcinoma (NSCLC) (2). Squamous cell carcinoma, adenocarcinoma, and large cell carcinoma are the major histologic types of NSCLC....

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  • Multidisciplinary landscape assessment, or MLA, is a set of methods developed by CIFOR scientists to determine ‘what is important to local communities, in terms of landscape, environmental services, and resources’. The approach is rooted in social (anthropology, ethnobotany and socio-economics) as well as natural sciences (botany, ecology, geography and pedology); was tested and used in different countries (Bolivia, Cameroon, Gabon, Indonesia, Mozambique and Philippines). The methods are fully detailed in four languages: English, French, Indonesia and Spanish (Sheil et al.

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  • 6 Molecular Approaches to Behavioural Ecology Using Molecules to Study Behaviour Behavioural ecology is a branch of biology that seeks to understand how an animal’s response to a particular situation or stimulus is influenced by its ecology and evolutionary history.

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  • Molecular dynamics (MD) simulations have played increasing roles in our understanding of physical and chemical processes of complex systems and in advancing science and technology. Over the past forty years, MD simulations have made great progress from developing sophisticated theories for treating complex systems to broadening applications to a wide range of scientific and technological fields. The chapters of Molecular Dynamics are a reflection of the most recent progress in the field of MD simulations....

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  • The field of molecular biophysics is introduced in the following pages. The presentation focuses on the simple underlying concepts and demonstrates them using a series of up to date applications. It is hoped that the approach will appeal to physical scientists who are confronted with biological questions for the first time as they become involved in the current biotechnological revolution. The field of biochemistry is vast and it is not the aim of this textbook to encompass the whole area.

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  • Tham khảo sách 'systems and computational biology – molecular and cellular experimental systems', kỹ thuật - công nghệ, cơ khí - chế tạo máy phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • For elucidating protein–protein interactions, many methodologies have been developed during the past two decades. For investigation of interac-tions inside cells under physiological conditions, yeast is an attractive organism with which to quickly screen for hopeful candidates using versa-tile genetic technologies, and various types of approaches are now avail-able.

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  • Moreover, we will present estimates for different scenarios – of slow and rapid adoption of the new technology – that should cover the range of possible out- comes with a good approximation. Third and last, our approach neglects some of the positive effects exerted by the introduction of cloud computing, mainly the cre- ation of new network effects and the positive externalities due to energy savings. Their consideration would be subject to excessive uncertainty, but because of this we can look at our estimates of the impact of cloud computing on the economy as conservative estimates.

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  • Our October 2012 box generated many comments, criticisms, and suggestions. In this paper, we restate our methodology, revisit our results, examine their robustness, and consider a number of extensions. Section II presents our estimation approach and reports our baseline results. Our forecast data come from the spring 2010 IMF World Economic Outlook (IMF, 2010c), which includes forecasts of growth and fiscal consolidation—measured by the change in the structural fiscal balance—for 26 European economies.

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  • Biomimetic recognition elements employed for the detection of analytes are commonly based on proteinaceous affibodies, immunoglobulins, single-chain and single-domain antibody fragments or aptamers. The alternative supra-molecular approach using a molecularly imprinted polymer now has proven utility in numerous applications ranging from liquid chromatogra-phy to bioassays.

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  • A tri-functional monomeric primase–polymerase domain encoded by the plasmid pIT3 fromSulfolobus solfataricusstrain IT3 was identified using a structural–functional approach. The N-terminal domain of the pIT3 repli-cation protein encompassing residues 31–245 (i.e. Rep245) was modeled onto the crystallographic structure of the bifunctional primase–polymerase domain of the archaeal plasmid pRN1 and refined by molecular dynamics in solution.

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  • Cellular regulation is a result of complex interactions arising from DNA–protein and protein–protein binding, autoreg-ulation, and compartmentalization and shuttling of regula-tory proteins. Experiments in molecular biology have identified these mechanisms recruited by a regulatory net-work.Mathematicalmodelsmaybe used to complement the knowledge-base provided byin vitroexperimental methods. Interactions identified byin vitroexperiments can lead to the hypothesis of multiple candidate models explaining the in vivo mechanism. ...

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  • Making vocational degree qualifications comparable and easily readable is at the heart of the Bologna Process. Methods of achieving this based purely on duration of study are fallible and give little information as to how graduates will perform in the workplace. A more robust outcome-based approach was developed by the Tuning Project (http://tuning.unideusto.org/tuningeu), a sector-wide project to agree learning outcomes/competences for all disciplines in Higher Education in Europe.

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  • This life-course approach is supported by a growing literature that documents how many adult health conditions have their origins in childhood and are affected by childhood risk, protective, and health-promoting influences. 7 Mounting evi- dence demonstrates how prenatal and early childhood risks that interfere with growth can increase the risk of ischemic heart disease, hypertension, obesity, and diabetes. Early exposure to infections and environmental toxins increase the like- lihood of cancer, hypertension and stroke, and neurodegenerative diseases.

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  • Like the population in general, the nursing workforce is aging, and impending retirements are likely to exacerbate future nursing shortages. In Australia, the proportion of nurses and midwives age 50 years and over increased from 29.1% to 34.9% from 2004 to 2008. In New Zealand, the average age of the practicing nurses is 47. With a large cohort of nurses expected to retire over the next 5 years, a major challenge exists to ensure an adequate supply of nurses in the coming years.

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