Molecular basis

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The Hoover's Sign of Pulmonary Disease: Molecular Basis and Clinical Relevance...

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  • Cytokine receptors are crucial for the maintenance, regulation and growth of cells in multicellular organisms. As a common theme in cytokine signal-ling, single-span receptor chains are assembled in the cell membrane by a ligand enabling cross-activation of the aligned cytoplasmic receptor domains.

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  • Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học Journal of Biology đề tài: X-chromosome inactivation: the molecular basis of silencing...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: "The molecular basis of lung cancer: molecular abnormalities and therapeutic implications...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Application of the comprehensive set of heterozygous yeast deletion mutants to elucidate the molecular basis of cellular chromium toxicity...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus...

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  • Chapter 16 - The molecular basis of inheritance. The chapter describe the contributions of the following people: Griffith; Avery, McCary, and MacLeod; Hershey and Chase; Chargaff; Watson and Crick; Franklin; Meselson and Stahl; describe the structure of DNA; describe the process of DNA replication; include the following terms: antiparallel structure, DNA polymerase, leading strand, lagging strand, Okazaki fragments, DNA ligase, primer, primase, helicase, topoisomerase, single-strand binding proteins.

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  • The genomics revolution of the past decade has greatly enhanced our understanding of the genetic composition of living organisms including many plant species of economic importance. Complete genomic sequences of Arabidopsis and several major crops, together with high-throughput technologies for analyses of transcripts, proteins and mutants, provide the basis for understanding the relationship between genes, proteins and phenotypes.

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  • Clostridium perfringense-toxin is produced by toxinotypes B and D strains. The toxin is the aetiological agent of dysentery in newborn lambs but is also associated with enteritis and enterotoxaemia in goats, calves and foals. It is considered to be a potential biowarfare or bioterrorism agent by the US Government Centers for Disease Control and Prevention.

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  • Dr. Sharon Rounds, the editor for this series who invited us to write a book on rare lung diseases, developed the idea after attending the 2004 Lymphangioleiomyomatosis (LAM) Foundation annual research meeting. She was a keynote speaker at that event (during her tenure as the president of the American Thoracic Society) and was witness to the power of patient advocacy and the mission-based scientific effort that had brought this rare disease of women from obscurity to clinical trials with targeted molecular therapies in under a decade.

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  • Understanding the forces that influence natural variation within and among populations has been a major objective of evolutionary biology for decades (Csilléry et al., 2010). It can be problematic, as natural populations may have complex demographic histories: size and range changes over time can lead to bottlenecks, fusions and expansions that leave signatures on the genetic composition of the population (Avise, 2004). Detection and analysis of genetic diversity can help us to understand the molecular basis of various biological phenomena in these natural systems.

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  • This is because IT uses primers based on allele sequences of functionally characterized genes, and thus specific banding patterns corresponding to plant phenotypes can be identified (Cernák, 2008; Cernák et al., 2008; Gizaw, 2011). However, development of such markers depends on the availability of robust genomic databases holding several target sequences for IT marker development. Functional gene characterization criteria might be limiting factors, since it is not possible to establish gene functions in a molecular ecological sense for all genes.

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  • In Germany, credit transfers have traditionally been the predominant form of payment transaction. However, their share of the total volume of payment transactions has decreased in recent years because more suitable payment instruments, especially direct debits, are being used for certain purposes (eg for the collection of identical payments due on a regular basis).

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  • A novel class of molecular chaperones co-ordinates the assembly and targeting of complex metalloproteins by binding to an amino-terminal peptide of the cognate substrate. We have previously shown that the NarJ chaperone interacts with the N-terminus of the NarG subunit coming from the nitrate reductase complex, NarGHI.

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  • Welcome to the home of the online edition of The Cancer Handbook which provides a comprehensive overview of all major areas of cancer research and oncology. This title differs from existing oncology textbooks and reference works in that it bridges the gap between the molecular biology of cancer and clinical diagnosis and treatment. As more and more laboratory research is applied to clinical management, e.g. the use of monoclonal antibodies as drugs, it is important that clinicians understand the aetiology of the disease and the molecular basis of the new therapeutic approaches. ...

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  • Glyphosate (N-phosphonomethyl-glycine) is the most widely used herbicide in the world: glyphosate-based formulations exhibit broad-spectrum herbi-cidal activity with minimal human and environmental toxicity.

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  • IgG molecules are exposed on a regular basis to acidic conditions during immunoaffinity purification procedures, as well as during the production of some therapeutic immunoglobulin preparations. This exposure is known to induce in them an antigen-binding polyreactivity. The molecular mecha-nisms and the possible biological significance of this phenomenon remain, however, poorly understood.

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  • The inhibition of phosphatases by adenosine 5¢-phosphorothioate (AMPS) was first reported in the late 1960s; however, the structural basis for the inhibition has remained unknown. Here, it is shown that AMPS is a submi-cromolar inhibitor of class C acid phosphatases

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  • Uncovering Recurrent Submicroscopic Rearrangements As a Cause of Disease For five decades since Fred Sanger's (1) seminal discovery that proteins have a specific structure, since Linus Pauling's (2) discovery that hemoglobin from patients with sickle cell anemia is molecularly distinct, and since Watson and Crick's (3) elucidation of the chemical basis of heredity, the molecular basis of disease has been addressed in the context of how mutations affect the structure, function, or regulation of a gene or its protein product.

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