Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: What do measurements of molecular biomarkers in different body fluids really tell us...
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: In silico evidence for the species-specific conservation of mosquito retroposons: implications as a molecular biomarker...
Many cancer patients are diagnosed at a stage in which the cancer is too far advanced to be cured, and most cancer treatments are effective in only a minority of patients undergoing therapy. Thus, there is tremendous opportunity to improve the outcome for people with cancer by enhancing detection and treatment approaches. Biomarkers will be instrumental in making that transition.
(BQ) Part 1 book "Molecular histopathology and tissue biomarkers in drug and diagnostic development" presentation of content: Histopathology - A canvas and landscape of disease in drug and diagnostic development, histopathology in mouse models of rheumatoid arthritis, markers used for visualization and quantification of blood and lymphatic vessels, image analysis tools for quantification of spinal motor neuron subtype identities,...
(BQ) Part 1 book "Molecular histopathology and tissue biomarkers in drug and diagnostic development" presentation of content: Final recommendations, three companion diagnostic development paths, implementing a multi analyte immunohistochemistry panel into a drug development program, cutpoint methods in digital pathology and companion diagnostics,...
Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field.
Pancreatic cancer is one of the most fatal human malignancies with extremely poor
prognosis making it the fourth leading cause of cancer-related deaths in the United
States. The molecular mechanisms of pancreatic carcinogenesis are not well
understood. The major focus of these two books is towards the understanding of the
basic biology of pancreatic carcinogenesis, identification of newer molecular targets
and the development of adjuvant and neoadjuvant therapies.
Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : Emerging concepts in biomarker discovery; The US-Japan workshop on immunological molecular markers in oncology
Ankylosing Spondylitis (AS) was first described possibly at the end of the XVII
century by Buckley (1931) and Connor, but it was only recognized after the radiologic
descriptions of Bechterew, Strumpell and Marie, during the XIX century. In 1964 the
American Rheumatism Association classified AS as a distinct disease. About forty
years ago (1973), Schlosstein and Brewerton published simultaneously but
independently the association of AS with the Class I allele B*27.
Ovarian cancer can no longer be considered one disease entity, but a heterogeneous group
of diseases. Our understanding of its clinical and molecular complexity is improving nota‐
bly over the last decade. This is of utmost importance when it comes to determine the most
adequate treatment strategy for each individual patient. Despite not being the most frequent
tumor, ovarian cancer has the highest mortality rate amongst gynecological cancers.
Porcine reproductive and respiratory syndrome (PRRS) is one of the most significant swine diseases
worldwide. Despite its relevance, serum biomarkers associated with early-onset viral infection, when clinical signs
are not detectable and the disease is characterized by a weak anti-viral response and persistent infection, have not
yet been identified. Surface-enhanced laser desorption ionization time of flight mass spectrometry (SELDI-TOF MS)
is a reproducible, accurate, and simple method for the identification of biomarker proteins related to disease in
Nutrigenomics, proteomics and metabolomics are three
new disciplines that will contribute to the rapid development
of functional foods. Bioinformatics is a new tool that uses
computer database technology to integrate data from
multiple, and sometimes disparate, disciplines. Already
these disciplines and tools have improved our understanding
of food science and human nutrition. Discoveries in genetics
make it possible to understand the effects of nutrients in
processes at the molecular level in the body and also the
variable effects of dietary components on each individual.
Recent reductions in cancer mortality are
due in part to risk reduction behaviors like
smoking cessation and more strongly to early
detection of cancer coupled with appropriate
therapy. Yet, there are no validated molecular
biomarker tests for the early detection of any
cancer (see Table I). Among the list of Food
and Drug Administration (FDA)-approved
biomarkers, none have been approved for
cancer early detection and screening.
Glucose as a source of energy is centrally important to our understanding
of life. We investigated the cell division–quiescence behavior of the fission
yeastSchizosaccharomyces pombeunder a wide range of glucose concentra-tions (0–111 mM). The mode of S.
Many people can work during chemotherapy, as long as they
match their schedule to how they feel. Whether or not you can
work may depend on what kind of work you do. If your job
allows, you may want to see if you can work part-time or work
from home on days you do not feel well.
Many employers are required by law to change your work
schedule to meet your needs during cancer treatment. Talk
with your employer about ways to adjust your work during
chemotherapy. You can learn more about these laws by talking ...
ider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication, referencing or personal use of the work must explicitly identify the original source. As for readers, this license allows users to download, copy and build upon published chapters even for commercial purposes, as long as the author and publisher are properly credited,...
A major challenge in clinical periodontics is to find a reliable molecular marker of
periodontal support loss with high sensitivity, specificity and utility (Buduneli & Kinane
2011). Molecules derived from inflamed host tissue and pathogenic bacteria have the
potential of being used as markers of periodontitis; however, molecular markers of bone
resorption have advantages as they relate to specificity for bone, easy detection, pre-analytic
stability and availability of sensitive and specific assays for detection (Forde et al. 2006).
In this review, will be summarize the principle of these new methodologies and the impact
of omics-techniques, mainly genomic-transcriptomics (analysis of single nucleotide
polymorphisms or gene-expression) and proteomic (identification and quantification of
proteins), in the knowledge of different aspects of allergy diseases (diagnosis, screening,
monitoring of treatment, protective or risk biomarkers and drug development) and the
advance to define the personalized and molecular medicine in this complex kind of diseases....
This book is unique among its peers as it offers a broad international perspective and
discusses practice approaches from around the globe. In addition, key elements of
emergency medicine practice are covered for the reader discussing historical and
cutting edge approaches and their scientific basis. The chapters that make up this
textbook should be of interest to any reader who treats or is interested in the treatment
of the emergency patient whether the patient is located in the pre-hospital, emergency
department or in-hospital settings....
The book Renal Failure – The Facts consists of some facts about diagnosis,
etiopathogenis and treatment of acute and chronic renal failure. Acute, as well as
chronic renal failure is great medical problems and their treatment is a burden for the
budget of each government.
Acute kidney injury (AKI), previously termed acute renal failure, is a frequent clinical
condition in critically ill patients especially, in intensive care units (ICU). Its incidence
varies from 1-7 % of all hospitalized patients to 30-50 % of patients in ICU....