Molecular changes

Xem 1-20 trên 156 kết quả Molecular changes
  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Dominance induction of fruitlet shedding in Malus × domestica (L. Borkh): molecular changes associated with polar auxin transport

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  • These research teams study for example the impact and mechanisms of greenhouse gas emissions and atmospheric pollutant on climate, ozone depletion and carbon sinks (oceans and inland waters, forests and soil). They do research to understand the mechanisms and assess the impact of global change on the water cycle, water quality and availability, as well as soil functions and quality to provide the bases for management tools for sustainable water systems. Biodiversity and ecosystems are analysed to understand and minimise the negative impacts of human activities.

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  • Over the past 20 years, technological advances in molecular biology have proven invaluable to the understanding of the pathogenesis of human cancer. The application of molecular technology to the study of cancer has not only led to advances in tumor diagnosis, but has also provided markers for the assessment of prognosis and disease progression. The aim of Molecular Analysis of Cancer is to provide a comprehensive collection of the most up-to-date techniques for the detection of molecular changes in human cancer.

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  • Lung cancer is the most frequent cause of cancer deaths in both men and women in the U.S. (1). Although tobacco smoking is accepted as the number one cause of this devastating disease, our understanding of the acquired genetic changes leading to lung cancer is still rudimentary. Lung cancer is classifi ed into two major clinic-pathological groups, small cell lung carcinoma (SCLC) and non-small cell lung carcinoma (NSCLC) (2). Squamous cell carcinoma, adenocarcinoma, and large cell carcinoma are the major histologic types of NSCLC....

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  • As a research scientist in the area of human nutrition, I have observed a sea change in emphasis within my field over the past 10–15 years. There have always been dynamics within the subject: During the first half of the twentieth century, scientists grappled with discovering the essential micronutrients and with characterizing the biological effects of their deficiency. This interest in “too little” was supplanted in the mid-1980s by a preoccupation with too much—too much fat, too much sugar, and too much obesity.

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  • Circular dichroism (CD) spectra of two major hemoglobin components (Hb), HbI and HbIV, from Oncorhyncus mykiss(formerly Salmo irideus) trout were evaluated in the range 250–600 nm. HbI is characterized by a complete insensitivity to pH changes, while HbIV presents the Root effect. Both reduced [iron(II) or oxy] and oxidized (met) forms of the two proteins were studied at different pHs, 7.8 and 6.0, to obtain information about the pH effects on the structural features of these hemoglobins.

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  • The scientific evidence is now overwhelming: climate change presents very serious global risks, and it demands an urgent global response. This independent Review was commissioned by the Chancellor of the Exchequer, reporting to both the Chancellor and to the Prime Minister, as a contribution to assessing the evidence and building understanding of the economics of climate change. The Review first examines the evidence on the economic impacts of climate change itself, and explores the economics of stabilising greenhouse gases in the atmosphere.

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  • A thermodynamic model for heterogeneous mixtures involving multi-molecular sorption is proposed. Some complex relationships between sorption potential, diffusion, sorption kinetics polymer network change kinetics, chemical affinity energy of internal changes and physico- chemical properties of polymer network are obtained. This model has interpreted some experimental results of fluid sorption in polymer network. Proposed model may be also used for study of other problems in heterogeneous mixture of fluid and polymers.

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  • Lecture Biology - Chapter 17: Genome sequencing, molecular biology, and medicine. The topics discussed in this chapter are: How do defective proteins lead to diseases? What kinds of DNA changes lead to diseases? How does genetic screening detect diseases? What is cancer? How are genetic diseases treated? What have we learned from the human genome project?

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  • HIV-1 protease (PR) and two drug-resistant variants – PR with the V82A mutation (PRV82A) and PR with the I84V mutation (PRI84V) – were studied using reduced peptide analogs of five natural cleavage sites (CA-p2, p2-NC, p6 pol -PR, p1-p6 and NC-p1) to understand the structural and kine-tic changes. The common drug-resistant mutations V82A and I84V alter residues forming the substrate-binding site. Eight crystal structures were refined at resolutions of 1.10–1.60 A ˚ .

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  • Chapter 20 - Development and evolutionary change. This chapter includes contents: How does a molecular tool kit govern development? How can mutations with large effects change only one part of the body? How can differences among species evolve? How does the environment modulate development? How do developmental genes constrain evolution?

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  • Molecules, small structures composed of atoms, are essential substances for lives. However, we didn’t have the clear answer to the following questions until the 1920s: why molecules can exist in stable as rigid networks between atoms, and why molecules can change into different types of molecules. The most important event for solving the puzzles is the discovery of the quantum mechanics. Quantum mechanics is the theory for small particles such as electrons and nuclei, and was applied to hydrogen molecule by Heitler and London at 1927.

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  • Plant response to reduced water availability and other abiotic stress (e.g. metals) have been analysed through changes in water absorption and transport mechanisms and also by molecular and genetic approach. A relatively new aspects of fruit nutrition are presented in order to provide the basis for the improvement of some fruit quality traits. The involvement of hormones, nutritional and proteomic plant profiles together with some structure/function of sexual components have also been addressed.

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  • Thus, in living cells, the rates of anterograde and retrograde transport between the two organelles appear to have a substantial effect on the morphology of the Golgi. The effect of the balance between anterograde and retrograde transport on the morphology of the ER remains to be explored. Recently, increasing evidence has suggested that alteration in Golgi morphology during mitosis is not a passive process but rather an active one, which is highly coordinated with entry into mitosis and its progression.

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  • This textbook covers Plant Ecology from the molecular to the global level.

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  • A global research community of scientists is teasing out the biochemical mechanisms that regulate normal cellular physiology in a variety of organisms. Much of current research aims to understand the network of molecular reactions that regulate cellular homeostasis, and to learn what allows cells to sense stress and activate appropriate biochemical responses.

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  • As a research scientist in the area of human nutrition, I have observed a sea change in emphasis within my field over the past 10–15 years. There have always been dynamics within the subject: During the first half of the twentieth century, scientists grappled with discovering the essential micronutrients and with characterizing the biological effects of their deficiency. This interest in “too little” was supplanted in the mid-1980s by a preoccu- pation with too much—too much fat, too much sugar, and too much obesity.

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  • Over the next decade, the two laws also will provide for about $900 billion in new subsidies, including a substantial expansion of Medicaid and new tax credits to offset the cost of health insurance premiums for low- and middle-income families and small businesses. In each state, exchanges will be established to facilitate the purchase of coverage and the delivery of the subsidies. Some companies whose workers receive subsidies for health insurance through the exchanges could be required to pay penalties.

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  • The research field of gene therapy and the clinical practice of medicine evolving from the research are fast moving, ever-changing disciplines. On an almost daily basis, there appears in the media a “breaking story” of a gene-based research finding. An implication of the story is that this research breakthrough will speedily transform, in the next few years, into a marvelous new therapy in molecular genetic medicine

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  • The Project Gutenberg EBook of The Minds and Manners of Wild Animals by William T. Hornaday Copyright laws are changing all over the world. Be sure to check the copyright laws for your country before downloading or redistributing this or any other Project Gutenberg eBook. This header should be the first thing seen when viewing this Project Gutenberg file. Please do not remove it. Do not change or edit the header without written permission. Please read the "legal small print," and other information about the eBook and Project Gutenberg at the bottom ...

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