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A Novel Approach to Molecular Recognition Surface of Magnetic Nanoparticles Based on Host–Guest Effect
Over the past decade the topic of energy and environment has been acknowledged
among many people as a critical issue to be solved in 21st century since
the Kyoto Protocol came into effect in 1997. Its political recognition was put
forward especially at Heiligendamm in 2007, when the effect of carbon dioxide
emission and its hazard in global climate were discussed and shared universally
as common knowledge.
Encounters with Phagocytes
Phagocytosis and Inflammation Phagocytosis of microbes is a major innate host defense that limits the growth and spread of pathogens. Phagocytes appear rapidly at sites of infection in conjunction with the initiation of inflammation. Ingestion of microbes by both tissue-fixed macrophages and migrating phagocytes probably accounts for the limited ability of most microbial agents to cause disease.
A novel class of molecular chaperones co-ordinates the assembly and
targeting of complex metalloproteins by binding to an amino-terminal
peptide of the cognate substrate. We have previously shown that the NarJ
chaperone interacts with the N-terminus of the NarG subunit coming from
the nitrate reductase complex, NarGHI.
The crystal structure ofPterocarpus angolensislectin is determined in its
ligand-free state, in complex with the fucosylated biantennary complex type
decasaccharide NA2F, and in complex with a series of smaller oligosaccha-ride constituents of NA2F. These results together with thermodynamic
binding data indicate that the complete oligosaccharide binding site of the
lectin consists of five subsites allowing the specific recognition of the penta-saccharide GlcNAcb(1–2)Mana(1–3)[GlcNAcb(1–2)Mana(1–6)]Man. ...
The cystine-knot motif, made up of three intertwined disulfide bridges, is a
unique feature of several toxins, cyclotides and growth factors, and occurs
in a variety of species, including fungi, insects, molluscs and mammals.
Growth factor molecules containing the cystine-knot motif serve as ligands
for a diverse range of receptors and play an important role in extracellular
Molecular mechanics calculations on conformers of
-HAla-NHMe and Ac-b
-HAla-NHMe indicate that low-energy conformations of the
b-amino acids backbone, corresponding to gauche rotamers
around the Ca–Cbbond, may overlap canonical backbone
conformers observed for a-amino acids. Therefore, Sub-stance P (SP) was used as a model peptide to analyse the
structural and biological consequences of the substitution of
-HAla or (S)-b
It is my privilege to contribute the foreword for this unique volume entitled: “Plant
Tissue Culture Engineering,” edited by S. Dutta Gupta and Y. Ibaraki. While there have
been a number of volumes published regarding the basic methods and applications of
plant tissue and cell culture technologies, and even considerable attention provided to
bioreactor design, relatively little attention has been afforded to the engineering
principles that have emerged as critical contributions to the commercial applications of
Thermodynamics is one of the most exciting branches of physical chemistry which has greatly contributed to the modern science. Being concentrated on a wide range of applications of thermodynamics, this book gathers a series of contributions by the finest scientists in the world, gathered in an orderly manner. It can be used in post-graduate courses for students and as a reference book, as it is written in a language pleasing to the reader. It can also serve as a reference material for researchers to whom the thermodynamics is one of the area of interest....
The potential value of artificial neural networks (ANNs) as a predictor of malignancy has
now been widely recognised. The concept of ANNs dates back to the early part of the 20th
century; however, their latest resurrection started in earnest in the 1980s when they were
applied to many problems in the areas of pattern recognition, control, and optimisation.
Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Mechanical tuning of molecular machines for nucleotide recognition at the air-water interface
Geochemical Investigations in Earth and Space Science: A Tribute to Isaac R. Kaplan is the
written product of a technical session organized for the 2002 Geological Society of America in
recognition of Isaac (Ian) Kaplan’s many contributions to various fields of geochemistry. This
volume is a collection of 29 papers written by former students, post-doctoral researchers, friends
and colleagues from countries all over the world (including Sweden, Japan, Taiwan, New
Zealand, Australia, Israel and the United States)....
Almost since their inception, the natural sciences, those fields that use the scientific
method to study nature, have been divided into two branches: the biological
sciences and the physical sciences. In part, this division can be viewed as a convenient
social contrivance. However, over time it has also served more functional
purposes. Physical scientists, when seeking the fundamental laws, have found it
necessary to focus on the simplest of systems—elementary particles, atoms, and
molecules—items clearly not alive.
Xylanase A from the phytopathogenic bacteriumErwinia chrysanthemiis
classified as a glycoside hydrolase family 30 enzyme (previously in family 5)
and is specialized for degradation of glucuronoxylan. The recombinant
enzyme was crystallized with the aldotetraouronic acidb-D-xylopyranosyl-(1fi4)-[4-O-methyl-a-D-glucuronosyl-(1 fi2)]-b-D-xylopyranosyl-(1 fi4)-D-xylose as a ligand.
The level of intracellular proteins is mainly regulated through modifications
by ubiquitin ligases that target them for degradation. Members of the
NEDD4 family of E3 ubiquitin ligases, such as Itch (atrophin-1 interacting
protein 4), possess up to four WW domains for specific association with
PY motif-containing substrates.
Despite increasing international recognition of the threat posed by terrorists’ use of the
Internet in recent years, there is currently no universal instrument specifically addressing
this pervasive facet of terrorist activity. Moreover, there is limited specialized training
available on the legal and practical aspects of the investigation and prosecution of terrorism
cases involving the use of the Internet. The present publication complements
the existing resources developed by UNODC in the areas of counter-terrorism, cybercrime
and rule of law.
Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí y học Molecular Biology cung cấp cho các bạn kiến thức về ngành sinh học đề tài: Efficient unfolding pattern recognition in single molecule force spectroscopy data...