Skeletal muscle contractions power human body movements and are essential for
maintaining stability. Skeletal muscle tissue accounts for almost half of the human body
mass and, in addition to its power-generating role, is a crucial factor in maintaining
homeostasis. Given its central role in human mobility and metabolic function, any
deterioration in the contractile, material, and metabolic properties of skeletal muscle has an
extremely important effect on human health.
The nuclear pore complex (NPC) is the only gateway for molecular traf-ficking across the nuclear envelope. The NPC is not merely a static
nuclear-cytoplasmic transport gate; the functional analysis of nucleoporins
has revealed dynamic features of the NPC in various cellular functions,
such as mitotic spindle formation and protein modification.
The spleen is the intra-abdominal organ most often injured as a result of blunt trauma. The
spleen is the most vascular organ of the body and, for this reason, splenic injury is
potentially life threatening. The most common mechanism for such injury is motor vehicle
collision. Left lower rib fractures are suggestive of spleen injury, although an intact rib cage
does not exclude spleen trauma.