Neuroimaging in dementia

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  • In 1871, over 30 years before Alois Alzheimer published his seminal cases, James Crichton - Browne may have been among the fi rst physicians to remark upon the relationship between “ brain wasting ” and “ premature dotage ” in a letter to Charles Darwin (Snyder & Pearn, 2007 ). Age - related mental deterioration as an entity had been recognized virtually for recorded history (Boller et al., 2007 ; Mandell & Albert, 1990 ).

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  • While history and examination will always remain the foundation of neurolog- ical diagnosis, MRI and CT have now become the most important diagnostic tests used by neurologists and neurosurgeons. These tests are critical not only for confirming clinical diagnosis, but in many cases will give additional infor- mation absolutely essential to patient care. Modern clinical diagnosis and treat- ment of central nervous system disorders relies heavily upon neuroimaging. In some cases, the optimal management of clinical problems affecting patients with brain tumors, strokes, etc.

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  • Magnetic resonance spectroscopy (MRS), unlike conventional magnetic resonance imaging (MRI), provides information on the brain’s chemical environment (rather than neuroanatomical structure) and the data are most commonly presented as line spectra. This capacity for determining brain metabolite concentrations provides the basis for clinical investigation of, and differentiation between, neurological and neurosurgical conditions.

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Clinical and neuroimaging correlates of abnormal short-latency Somatosensory Evoked Potentials in elderly vascular dementia patients: A psychophysiological exploratory study...

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