.Treatment of Pediatric Neurologic Disorders
.NEUROLOGICAL DISEASE AND THERAPY Advisory Board Louis R. Caplan, M.D.
Professor of Neurology Harvard University School of Medicine Beth Israel Deaconess Medical Center Boston, Massachusetts
William C. Koller, M.D.
Mount Sinai School of Medicine New York, New York
John C. Morris, M.D.
Friedman Professor of Neurology Co-Director, Alzheimer’s Disease Research Center Washington University School of Medicine St. Louis, Missouri
Bruce Ransom, M.D., Ph.D.
he Second Edition of this single-authored volume integrates multiple disciplines of basic and clinical research to help clinicians further develop the best possible care for the rehabilitation of patients with neurologic diseases. From the readable descriptions of the structures and functions of pathways for movement and cognition, the reader comes to understand the potential for training induced, pharmacologic,
NEUROLOGIC DISEASE IN WOMEN
insomnia, and anxiety. Less than half of these cases are correctly identified as alcohol-related. Women are also more likely to be admitted to non–alcohol-specific treatment, such as general psychiatric units rather than conventional alcohol treatment services (81) and are more likely to drop out of treatment (85). Because female alcoholics often have low self-esteem and feelings of shame and embarrassment, they may balk at confrontational techniques and require more supportive and skill-building approaches.
Neuro-oncology has evolved substantially as a
clinical and research discipline over the past few
decades. Initially the province of isolated devotees,
it has become a well-recognized subspecialty
of neurology, oncology, and neurosurgery. The
Society for Neuro-Oncology, founded just five
years ago, now has almost 1000 members. Most
tertiary care hospitals have staff physicians who
consider themselves neuro-oncologists. These physicians
typically are involved in the evaluation and
management of neurologic complications of systemic
cancer and its treatment, as well as of primary
(BQ) Part 2 book "Diagnostic imaging of the foot and ankle" presents the following contents: Midfoot, forefoot, abnormalities of the plantar soft tissues, neurologic diseases, diseases not localized to a specific site, systemic diseases that involve the foot, tumorlike lesions, normal variants.
(BQ) Part 2 book "Elsevier's integrated review genetics" presents the following contents: Musculoskeletal disorders, neurologic diseases, cardiopulmonary disorders, renal, gastrointestinal and hepatic disorders, disorders of sexual differentiation and development, population genetics and medicine, modern molecular medicine.
Diseases of the nervous system number in the hundreds and are too
numerous and varied to be learned in their entirety. Hence the common
practice of subdividing them into categories—traumatic, vascular, neoplastic,
infective, metabolic, degenerative, congenital, and so forth. In
our textbook, Principles of Neurology, we describe the various categories
of neurologic disease and the main diseases that constitute each
This book has its roots in our perceived need for a concise text to assist the practitioner
in prioritizing likely diagnoses when encountering a patient complaining of
neurological problems or defi cits. Though many references exist on neurological
disease and differential diagnoses, few offer easily referable likely diagnoses based
on common complaints and presentation. When one approaches differential diagnosis
in neurology, there is frequently a feeling of overwhelming information.
Although a general understanding persists that the
human brain functions similarly in women and in men,
an increasing body of knowledge indicates that neuronal
connectivity, recruitment, and disease patterns exhibit
gender differences. Imaging techniques such as positron
emission computerized tomography (PET) and single
photon emission computerized tomography (SPECT)
have highlighted some gender-based differences in human
After the publication of Emergency Neurology: Principles and Practice, many emergency
medicine residents inquired whether a handbook based on the main text
would be available. As a result, we developed a handbook to be carried by emergency
physicians, extending our initial goal of disseminaing the principles of
emergency neurology to emergency physicians and providing a ready resource
in caring for patients with neurological emergencies. As we embarked upon the
handbook project, we realized that this is a daunting challenge.
In writing An Atlas of Parkinson’s Disease and
Related Disorders, I have been conscious of the
need to find an appropriate match between the
text and the illustrative material. The text is
designed to provide a basic overview of the conditions
discussed, inevitably concentrating on those
areas which lend themselves best to photographic
illustration. Some movement disorders, by their
very nature, do not lend themselves to still
photography whereas others, characterized by
sustained postures, are ideally suited to the technique.
This book has been in the planning stage for a consider-
able period of time. Each of us has been involved in the
care of patients with Parkinson’s disease for many years,
and we have become keenly aware of the need for a book
that will help patients and their families develop a fuller
understanding of what living with Parkinson’s is like.
When people ﬁrst learn of the diagnosis of Parkinson’s
disease, they generally know very little about this illness.
Understandably, a myriad of questions arise.
Advances in the diagnosis, prevention, treatment and cure of neurological diseases
are based upon scientific discovery. The journey from discovery to treatment is often
arduous and involves both basic and clinical science. Over the ages, multiple intertwined
paths of discovery connect the recognition of distinct diseases of the nervous
system to exquisite diagnostic descriptions, which, when coupled with the scientific
understanding of the disease, have allowed the development of effective treatments
Over the past few decades the field of neurology has seen spectacular developments in diagnostic techniques, most vividly
exemplified by modern neuroimaging and molecular genetics. Although not always at the same speed this evolution has
gone hand in hand with an enlarging armentarium of effective therapies to treat neurological disease.
James Parkinson described Parkinson’s disease in his memorable Essay on the Shaking Palsy in 1817. Since then,
and particularly in recent years, there has been tremendous progress in our understanding of this complex and fascinating
neurological disorder. Briefly, we have learned that it is not only manifest by motor symptoms but also
that there is a whole range of non-motor features, including autonomic, psychiatric, cognitive and sensory impairments.
We now know how to distinguish better clinically between Parkinson’s disease and the various parkinsonian
(BQ) Part 2 book "Rogers' textbook of pediatric intensive care" presents the following contents: Respiratory disease, neuromuscular disease, neurologic disease, cardiac disease, immunologic diseases, infectious diseases, nutritional and gastrointestinal disorders, oncologic and hematologic disorders, renal, endocrine and metabolic disorders.
Sleep is a function of the brain. However, the ultimate physiological function
of sleep remains enigmatic and unknown despite recent extensive research of this
ubiquitous and important brain activity. Sleep intervenes in functions of somatic
growth, regeneration, and memory. Sleep is important in medicine because it
modulates quality of life, while its disorders provoke family pathology, disturb
work routines, alter social activities, and, in general, affect the health of the
Neuro-ophthalmology is a subspecialty of neurology and ophthalmology that bridges
the gap between eye and brain. This issue of Neurologic Clinics describes the key
features and latest information on topics in neuro-ophthalmology of interest to practicing
neurologists and, in particular, highlights areas for which referral might be
reasonable to neuro-ophthalmologists.
A quick review of the table of contents for this issue illustrates the depth and
breadth of the neurologic topics that fall within neuro-ophthalmology.
Funny turns and chest pain – funny turns are an unusual presentation for
cardiac disease in children, much more commonly associated with simple
faints, or neurological disease such as epilepsy. Sudden collapse may be due to
arrhythmias, and collapse with exercise is a very worrying sign in a child with
significant left ventricular outflow tract obstruction such as aortic stenosis.
Most chest pain in children is due to musculoskeletal problems, especially in
older children. Coronary artery abnormalities, and hence chest pain due to
angina, is rare.