Nuclear medical

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  • This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and increase in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G.

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  • Safe and effective medical countermeasures, including vaccines, drugs, and diagnostics, are critical for responding to large-scale public health emergencies. Such situations, be they natural (e.g., pandemic influenza) or man-made (e.g., terrorism), have the potential to rapidly overwhelm public health and medical systems. America’s national security depends on having appropriately licensed chemical, biological, radiological, and nuclear medical countermeasures in its arsenal of defenses.

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  • In recent years, the remarkable advances in medical imaging instruments have increased their use considerably for diagnostics as well as planning and follow-up of treatment. Emerging from the fields of radiology, medical physics and engineering, medical imaging no longer simply deals with the technology and interpretation of radiographic images. The limitless possibilities presented by computer science and technology, coupled with engineering advances in signal processing, optics and nuclear medicine have created the vastly expanded field of medical imaging.

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  • Writing and rewriting a text such as Medical Imaging Physics over several editions presents two challenges. The first is to keep the information fresh and relevant. This is a particular challenge in medical imaging, because the field is evolving so rapidly. The third edition of this text was published in 1992, just 10 short years ago. Yet in that text no mention was made of topics such as photodiode or direct conversion digital x-ray imagers; digital mammography; digital fluoroscopy; power Doppler ultrasound; functional magnetic resonance imaging; elastography; or helical CT scanning.

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  • Everyday, millions of medical images are produced worldwide, to aid diagnosis and treat‐ ment of patients. A typical patient’s diagnostic work-up is often incomplete without a medi‐ cal imaging technique. The various techniques for achieving this have continued to evolve, from the basics through the sophisticated and now to the abstract.

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  • Nuclear Medicine is a fascinating application of nuclear physics. This wikibook is intended to support a basic introductory course in an early semester of an undergraduate program. It assumes that students have completed decent high school programs in maths and physics and are concurrently taking subjects in the medical sciences.

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  • The NCRP has long mcog&ed the need for a clear assessment of the magnitude of doses from various souroes of radiation to which the population of the U.S. is ocpo9ed. In anticipation of the need to gather data for input into this process five as&sament committees, each adhing a different source category, wem established, first in 1971 and then reestablished in 1986. NCRP reports assessing exposum from natural background, consumer products, and nuclear power gene ation have recently been published (NCRP, 1987% 1987b. 1987~)...

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  • The application of radiation in human health, for both diagnosis and treatment of disease, is an important component of the work of the IAEA. The responsibility for the increasingly technical aspects of this work is undertaken by the medical physicist. To ensure good practice in this vital area, structured clinical training programmes are required to complement academic learning. This publication is intended to be a guide to the practical implementation of such a programme for nuclear medicine.

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  • In September 2003, the National Institutes of Health (NIH) presented to the American people the goals of the NIH for medical research in the 21st century. Dr. Elias Zerhouni, who became director of the NIH in May 2002, had been Associate Dean for Research at Johns Hopkins School of Medicine before going to the NIH as the fi rst radiologist to head that agency. He had been trained in nuclear medicine while a resident in radiology at Hopkins.

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  • Tham khảo sách 'medical imaging in clinical practice_1', y tế - sức khoẻ, y học thường thức phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • Although several proteins undergo tyrosine phosphorylation at the nuclear envelope, we achieved, for the first time, the identification of tyrosine-phos-phorylation sites of a nuclear-membrane protein, emerin, by applying two mass spectrometry-based techniques.

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  • Hepatocyte nuclear factor-4 (HNF-4a), a member of the nuclear receptor superfamily, binds DNA exclusively as a homodimer. Dimerization con-trols important aspects of receptor function, such as DNA binding, protein stability, ligand binding and interaction with coactivators.

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  • In an era of spectacular medical advances, it is easy to become immune to the announcement of new “breakthroughs”. This in no way lessens the remarkable achievements of diagnostic imaging over the last few years in which the field of Nuclear Medicine has shared. To the outsider the specialty of Nuclear Medicine can appear confusing and esoteric since it operates in a world of invisible radioactive emissions, nuclear decay charts and obscure elements.

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  • The 20th century brought us the birth of the atomic age, with Albert Einstein’s understanding that E = MC2 in 1905, Ernest Rutherford’s theory of the structure of the atom in 1911, and the first sustained nuclear reaction in Chicago in 1942. While it brought the promise of a robust use of nuclear technologies for peaceful purposes, it also brought the reality of nuclear weapons in 1945. Those initial weapons were large, heavy, and complex to make and use. Moreover, only nations had nuclear weapons, not individuals or groups.

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  • The inner nuclear membrane protein MAN1 has been identified as an important factor in transforming growth factor b⁄bone morphogenic pro-tein (TGFb⁄BMP) signaling. Loss of MAN1 results in three autosomal dominant diseases in humans; all three characterized by increased bone density.

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  • A cDNA encoding a nuclear receptor subfamily I member in the platy-helminthSchistosoma mansoni(SmNR1) was identified and characterized. SmNR1 cDNA is 2406 bp long and contains an open reading frame encoding a 715 residue protein.

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  • The effects of physiologically relevant hypoxia on the catalytic activity of cytochromecoxidase (CytOX), mito-chondrial gene expression, and both nuclear and mito-chondrial encoded CytOX mRNA levels were investigated in murine monocyte macrophages, mouse C2C12 skeletal myocytes and rat adrenal pheochromocytoma PC12 cells. Our results suggest a coordinated down regulation of mito-chondrial genome-coded CytOX I and II and nuclear genome-codedCytOX IV andVbmRNAs during hypoxia.

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  • The naturally synchronous plasmodia of myxomycetes synthesize poly(b-L-malic acid), which carries out cell-specific functions. In Physarum polycephalum, poly(b-L-malate) [the salt form of poly(b-L-malic acid)] is highly concentrated in the nuclei, repressing DNA synthetic activity of DNA polymerases by the formation of reversible complexes. To test whether this inhibitory activity is cell-cycle-dependent, purified DNA polymerase a of P.

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  • Even before the events of September 11, 2001, threat assessments suggested that the United States should prepare to respond to terrorist attacks inside its borders. This report documents research into the use of military medical assets to support civil authorities in the aftermath of a chemical, biological, radiological, nuclear, or conventional high expl

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  • Current evidence indicates that chylomicron remnants (CMR) induce macrophage foam cell formation, an early event in atherosclerosis. Inflam-mation also plays a part in atherogenesis and the transcription factor nuclear factor-jB (NF-jB) has been implicated. In this study, the influence of CMR on the activity of NF-jB in macrophages and its modulation by the fatty acid composition of the particles were investigated using macro-phages derived from the human monocyte cell line THP-1 and CMR-like particles (CRLPs)....

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