Obesity and its associated disorders

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  • Obesity and its associated disorders, including diabetes and cardiovascular disease, have now reached epidemic proportions in the Western world, resulting in dramatic increases in healthcare costs. Understanding the pro-cesses and metabolic perturbations that contribute to the expansion of adi-pose depots accompanying obesity is central to the development of appropriate therapeutic strategies.

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  • Harrison's Internal Medicine Chapter 44. Abdominal Swelling and Ascites Abdominal Swelling Abdominal swelling or distention is a common problem in clinical medicine and may be the initial manifestation of a systemic disease or of otherwise unsuspected abdominal disease. Subjective abdominal enlargement, often described as a sensation of fullness or bloating, is usually transient and is often related to a functional gastrointestinal disorder when it is not accompanied by objective physical findings of increased abdominal girth or local swelling.

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  • It has been documented, for example, that high maternal pre-pregnancy weight and excessive weight gain during pregnancy are often associated with adverse pregnancy outcomes, including greater risks of gestational diabetes, childbirth complications, caesarean sections, hypertension and pre-eclampsia, and post-partum obesity. Women with severe (morbid) obesity are more likely to experience even poorer outcomes such as stillbirths or neonatal deaths.

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  • It’s the other four-letter word. The D-word. The D-bomb. DIET. Why do we hate that word so much? Hunger. Failure. Rules. Restrictions. Deprivation. Expectations. Rebound weight-gain. Eating disorders. Strained relationships. Bad foods. Bad moods. Bad breath. Guilt. There are so many negative associations with the word diet, it’s no wonder that over half the North American population is overweight. We hate dieting. It’s torturous. Tacky. Totally depressing. And even worse, dieting doesn’t seem to work.

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