The European Union’s CAREX database of occupational exposures to
carcinogens estimated that in the early 1990s 22-24 million workers in the
then 15 EU member states were exposed to carcinogens classiﬁed as group 1
by the International Agency for Research on Cancer – those known to cause
cancer in humans.
Overall, 32 million workers, 23 per cent of the working population,
had workplace exposures associated by the CAREX database with an
occupational cancer risk.
Even with “clean” technology and improved, modern,
workplace safety practices, the risks can be real.
A 2006 US study using the ﬁrm’s own ‘Corporate
Mortality File’, found staff employed at IBM computer
factories had high rates of a range of cancers linked to
exposures to chemicals and electromagnetic ﬁelds.
Studies have found similar problems in computer
factories in other countries.
Ofﬁce jobs too can have their risks.
Cancer, this complex group of diseases with serious implications not just for
individuals and their families, but also for society in general and health
systems in particular, remains an important health challenge in Slovenia, in
Europe and world-wide. At present, with more than 3 million new cases and
1.7 million deaths each year, cancer represents the second most important
cause of death and morbidity in Europe.
Genes contain the recipes for the
various proteins a cell needs to stay
healthy and function normally. Some
genes and the proteins they make can
influence how a breast cancer behaves
and how it might respond to a specific
treatment. Cancer cells from a tissue
sample can be tested to see which
genes are normal and abnormal. The
proteins they make can also be tested.
If the genetic recipe contains a mistake
the report will say “genetic mutation”
or “genetic abnormality.
GM-CSF is one of several naturally occurring glycoproteins
that regulate leukocyte production, migration and function.
It has been produced in different cell types, with different
properties that depend on the production process used. The
purpose of this work was to characterize the recombinant
human GM-CSF from an engineered Chinese hamster
ovary cell line grown in suspension and as adherent culture
for the identification of the glycosylation sites and the defi-nition of the glycosidic moiety, including the degree of site
This article offers a brief overview of the health evidence on Agent Orange and cancer, to help clinicians serve
Vietnam veteran patients and their family members. The evidence comes from several sources including studies of
Vietnam veterans, workers exposed to herbicides or dioxins (since dioxins contaminated the herbicide mixtures used
in Vietnam) in occupational settings, and studies of health effects among Vietnamese populations in the aftermath of
the war. This article does not offer a complete review of all these lines of evidence.
A variety of occupational risks is known to cause
cancer. Every year more than seven million people
die of cancer. Forty percent of these cases could be
prevented which means that one in every ten cancer
deaths is preventable through interventions targeted on
exposure in the working environment.
The articles in this issue of GOHNET highlight
some aspects of the problem and the prevention
of occupational cancer.
Given the rapid pace of research findings and clinical refinement related to cancer prevention and
treatment, the content of the NCI Thésaurus evolves rapidly. To keep the information as up to date as
possible, a new release is made every month. With nearly a dozen full time subject matter experts working
on different parts of the terminology, a well-structured and complex process is used to ensure accuracy and
coherence. NCI uses the Apelon, ...
Countless organizations have their own intricate and well-developed thesauri that have been refined over many
years. With consummate converters, these thesauri can become a strong and useful element on the semantic web.
Like the Thésaurus from the National Cancer Institute, many are available in an unusual form of XML, or not in
XML at all. As in this case, simple translations using standard XML parsers often will not be a reasonable solution
for making the transition to RDF or OWL.
The most time...
Very limited evidence was available to inform the following recommendations on
screening. No prospective studies have evaluated the impact of screening on survival, quality of
life, or morbidity from treatment for skin cancer nor are there data on the adverse effects of
screening for skin cancer. As experts in the treatment and epidemiology of skin cancer, the
guideline panel members were aware that some individuals are at increased risk for skin cancer
because of personal characteristics or history.
With advances in the management of acute myocardial infarction (AMI) the incidence of
mechanical complications continues to decline. Nevertheless, when they occur,
unfortunately, despite similar advances and growing experiences in the surgical
management of these problems, morbidity and mortality remain high. Post-myocardial
infarction ventricular septal defects (PI-VSD) have fascinated and challenged clinicians for
The National Highway Traffic Safety Administration (NHTSA) is an integral part of the United
States Department of Transportation (DOT) and its mission is to save lives, prevent injuries, and
reduce traffic-related health care and other economic costs associated with motor vehicle use and
highway travel. To accomplish this, NHTSA collects and analyzes motor vehicle crash data, and
develops, promotes, and implements educational programs, vehicle safety standards, research,
and enforcement programs.
During the last decades, cancer diseases have increased all over the world. The
low quality of food and strong pollution of environment are the main
prerequisites for carcinogenesis. The main problem for scientists is to find strategy
for prevention of cancer diseases. Therefore, the information about models for
studying carcinogenesis and mutagens which appear during cooking,
environmental pollutants, and tests for specific detection of carcinogens is
Transurethral biopsy of the prostate was another approach that had been described but
unlike the previous method described it required a general anaesthetic and a period of
hospitalization. Denton et al. held that an extensive transurethral prostatectomy would
nearly always confirm the diagnosis (Denton et al., 1967) and Grabstald commented that this
transurethral biopsy might be useful in advanced tumours (Grabstald, 1965b).
Psychological distress increases with the intensity of cancer pain. Cancer pain is often under-reported
and under-treated for a variety of complex reasons, partly due to a number of beliefs held by patients,
families and healthcare professionals. There is evidence that cognitive behavioural techniques that
address catastrophising and promote self-efficacy lead to improved pain management. Group format pain
management programmes could contribute to the care of cancer survivors with persistent pain.
Like several other implements of child abuse, motor vehicles are household necessities. If not used
properly, however, they can be deadly weapons. A ride in the family van, sports utility vehicle
(SUV), pickup truck or sedan can become lethal if adults do not take appropriate precautions,
including using proper child restraints and avoiding DUI restraints.
Before choosing or recommending information resources for men with prostate cancer, health-
care professionals should check that their content is clear, reliable and up to date.
Healthcare professionals should seek feedback from men with prostate cancer and their carers
to identify the highest quality information resources.
Healthcare professionals caring for men with prostate cancer should ascertain the extent to
which the man wishes to be involved in decision making and ensure that he has sufficient
information to do so.
A: high-fat diet can increase the risk of many cancers, including endometrial cancer.
Because fatty foods are also high-calorie foods, a high-fat diet can lead to obesity, which
is also an endometrial cancer risk factor. Some doctors think that fatty foods may have a
direct effect on estrogen levels, which can increase risk, too.
Exercise protects against endometrial cancer. Studies found that women who exercised
more had a lower risk of this cancer, while one study showed that women who spent
more time sitting had a higher risk....
More people today face a workplace cancer
risk than at any other time in history.
It’s just that most of them don’t know it.
A World Health Organisation (WHO)
study concluded 20-30 per cent of males and
5-20 per cent of females in the working-age
population could have been exposed to an
occupational lung cancer risk during their
Figures from the French national statistic
ofﬁce DARES published in 2005 revealed
more than 1 in 8 workers was exposed to
workplace substances that can cause cancer.
It concluded 13.
Investigate Review existing sources, like workplace sick leave, accident,
compensation and pension records. Don’t forget retired members – many
cancers take decades to emerge, so may only occur after a worker has ﬁnished
working. Newspaper reports may highlight local deaths linked to occupational
disease. Where there is a suspicion of a problem, dig deeper.
Surveys Do-it-yourself research can quickly identify problems. This need not
be a highly scientiﬁc and time-consuming business.