Pathological changes

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Injurious mechanical ventilation in the normal lung causes a progressive pathologic change in dynamic alveolar mechanics...

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  • In 1856, Rudolf Virchow published “Cellular pathology” based on macroscopic and microscopic observation of diseases, and described a triad of factors on thrombosis. The three components were vascular change, blood flow alteration, and abnormalities of blood constituents. Although Virchow originally referred to venous thrombosis, the theory can also be applied to arterial thrombosis, and it is considered that atherothrombus formation is regulated by the thrombogenicity of exposed plaque contents, local hemorheology, and blood factors.

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  • Forensic veterinary pathology is defi ned as the application of knowledge of veterinary pathology to the elucidation of evidence for the Courts. In other words, the purpose of conducting a forensic examination is: (a) to discover and record any injury, disease or abnormality, and (b) to interpret these fi ndings in a manner that allows a Court of Law to understand the cause(s) and signifi cance of any changes. Forensic pathology is a highly skilled task, and veterinarians undertaking forensic post-mortem examinations must be able to demonstrate that they are competent in this fi eld.

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  • Lung cancer is the most frequent cause of cancer deaths in both men and women in the U.S. (1). Although tobacco smoking is accepted as the number one cause of this devastating disease, our understanding of the acquired genetic changes leading to lung cancer is still rudimentary. Lung cancer is classifi ed into two major clinic-pathological groups, small cell lung carcinoma (SCLC) and non-small cell lung carcinoma (NSCLC) (2). Squamous cell carcinoma, adenocarcinoma, and large cell carcinoma are the major histologic types of NSCLC....

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  • In no department of Pathology has advance been so fitful and interrupted as in that dealing with blood changes in various forms of disease, though none now offers a field that promises such an abundant return for an equal expenditure of time and labour. Observations of great importance were early made by Wharton Jones, Waller, and Hughes Bennett in this country, and by Virchow and Max Schultze in Germany.

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  • The 32nd Japanese Hip Society (JHS) Congress was held November 6–8, 2005, in Niigata, Japan. Guest speakers from many countries and specialists for hip disease presented papers that focused on joint preservation for osteoarthritis of the hip, joint preservation for aseptic necrosis of the femoral head, treatment for epiphyseolysis capitis femoris, and up-to-date information and knowledge on joint arthroplasty. Altogether, there were many important presentations about joint preservation and replacement. This book covers the main themes of the congress....

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  • The pioneering cardiac surgeon Alain Carpentier, MD, PhD, developed a functional classification to reflect the underlying pathological changes that contributed to MR (Carpentier A. 1983) (Figure 4). As described in this classification, type I MR is characterized as normal leaflet motion but with annular dilatation or leaflet perforation; type II lesions are related to leaflet prolapse and may be caused by myxomatous disease, such as chord rupture or elongation, or by papillary muscle rupture or elongation; and type III lesions are caused by restricted leaflet motion.

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  • Hepatocellular carcinoma (HCC) used to be regarded as a rare disease. The increasing numbers of chronic hepatitis C virus carriers in the United States and subsequent increased incidence of HCC seen in most large medical centers means that it is no longer an uncommon disease for most gastroenterologists or oncologists to encounter. During the times when liver resection or systemic chemotherapy were the only real therapeutic modalities available, the outcomes were generally dismal, especially because most patients presented with advanced-stage tumors.

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  • There is a common belief, significantly shared by many beginning formal tertiary studies in education, that ‘education’ has a fixed meaning, and distinct aims, which can be unveiled either by turning up a dictionary or by consulting a favoured authority. So, in the very first lecture of every course I give, I stress that ‘education’ is a changing, contested and often highly personalised, historically and politically constructed concept. To illustrate this I read a few dictionary definitions of ‘education’, as well as a selected set of stated ‘aims of education’.

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  • At the other end of the food chain agricultural practices are going to change. The increased focus on environmental sustainability in society is reflected in the rapid growth for organic agriculture, while the use of modern biotechnology might be offering many new opportunities for agriculture in the EU. The enlargement process and further reforms of the CAP could lead to a drastically changed market and production situation.

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  • Azzaroli et al. dedicated their chapter to the most prescribed medications worldwide, namely non steroidal anti-inflammatory drugs (NSAIDs). These drugs are prescribed for pain management in musculoskeletal or osteoarticolar pathologies because of their analgesic and anti-inflammatory properties, however, major side effect associated with NSAIDs include gastrointestinal bleedings from both the upper and lower gastrointestinal tract.

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  • The second section of the book collects studies on pathophysiology of ischemic damage. This is an area where our knowledge has greatly advanced in the past decade, mainly due to the study of novel pathways of damage and of novel techniques to investigate them. Better knowledge of how brain tissue becomes damaged in stroke will hopefully lay the foundation for better therapies, be them recanalization (like thrombolysis) or neuroprotection (like hypothermia).

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  • Although the FAB classification failed to distinguish immunophenotypic groups of acute lymphoblastic leukemias, did not recognize the significance of myelodysplastic changes in acute myeloid leukemias or cytogenetic abnormalities in either leukemia type, and resulted in some subcategories of little clinical significance, this system provided very clear guidelines for classification.

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  • In recent years, all western industrialized countries, and to a growing extent even many developed and developing Asian nations, have witnessed a remarkable growth in numbers of older people [1]. Future projections anticipate continued increases, particularly in numbers of individuals who are 85 years and older [1]. Although US statistics have indicated recent declines in disability trends [2], overall numbers of older individuals living with disability and functional dependence are likely to increase given projected increases in life expectancy [3].

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  • The field of insect pathology has grown steadily since its inception as a formal academic discipline in the mid-1940s (Steinhaus, 1949). Concomitantly, the applied side of insect pathology has also grown considerably resulting in the commercial development of bacterial, viral, fungal and nematode entomopathogens as microbial control agents.

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  • The National Council on Radiation Protection and Measurements (NCRP) was requested by the US Department of Energy (DOE) to review the literature on the effects of radiation on aquatic organisms and develop a document that reviews the present understanding of such effects and provides guidance for a standard for the protection of populations of aquatic organisms.

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  • Aleksandra Klemba1,2, Magdalena Kowalewska3, Wojciech Kukwa4, Katarzyna Tonska1, Aleksandra Szybinska5, Malgorzata Mossakowska5, Anna Scinska4, Paweł Golik1,6, Kamil Koper1, Jakub Radziszewski7, Andrzej Kukwa4, Anna M Czarnecka1,2*, Ewa Bartnik1,6 Abstract Vulvar squamous cell carcinoma (VSCC) is a rare female genital neoplasm. Although numerous molecular changes have been reported in VSCC, biomarkers of clinical relevance are still lacking. On the other hand, there is emerging evidence on the use of mtDNA as a diagnostic tool in oncology.

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  • By transforming the paradigm for how health develops, a life-course approach provides a strong public policy rationale for health systemtransformation. It dem- onstrates how disadvantage during childhood diminishes future prospects by re- ducing a child’s health potential, which in turn directly harms educational out- comes and future social competence and accelerates the acquisition and severity of health problems in later years. 9 This approach emphasizes investments focused on prevention, health promotion, and improving the conditions of children’s lives.

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  • First of all, we are delighted to be able to provide the "Innovative Rheumatology" to everyone involved in the treatment and research of rheumatoid arthritis. In recent years, the treatment of Rheumatoid Arthritis has undergone tremendous changes due to methotrexate and biologics in large part. Until a decade ago, avoiding joint destruction in rheumatoid arthritis was not realistic for rheumatologist. However, prevention of joint deterioration is now possible, and the quality of life of patients with rheumatoid arthritis in long-term has been able to improve by advances in treatment.

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  • In recent years, the treatment of Rheumatoid Arthritis has undergone tremendous changes due to methotrexate and biologics in large part. Until a decade ago, avoiding joint destruction in rheumatoid arthritis was not realistic for rheumatologist. However, prevention of joint deterioration is now possible, and the quality of life of patients with rheumatoid arthritis in long-term has been able to improve by advances in treatment.

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