Pharmacological approaches

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  • Physiology plays a major role in the scientific foundation of medicine and other subjects related to human health and physical performance. Pharmacology is the science which deals with the effects of drugs on living systems and their use in the treatment of disease. This book is designed to enhance students’ understanding of physiology and pharmacology via a series of case studies involving human disease and its treatment. Traditional university teaching methods focus on informing students in terms of physiological and pharmacological theory.

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  • Maximum success in skeletal surgery depends on adequate access to and exposure of the skeleton. Skeletal surgery is simplified and expedited when the involved parts are sufficiently exposed. In orthopedic surgery, especially of the appendicular skeleton, a basic rule is to select the most direct approach possible to the underlying bone. Thus, incisions are usually placed very near the area of interest while major nerves and blood vessels are retracted.

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  • This book has its roots in our perceived need for a concise text to assist the practitioner in prioritizing likely diagnoses when encountering a patient complaining of neurological problems or defi cits. Though many references exist on neurological disease and differential diagnoses, few offer easily referable likely diagnoses based on common complaints and presentation. When one approaches differential diagnosis in neurology, there is frequently a feeling of overwhelming information.

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  • As the global epidemic of diabetes continues to expand, the prevalence of type 2 diabetes is predicted to double in the next 20 years. Continued population growth, increasing age, and worldwide globalization leading to changes in diet and patterns of physical inactivity have resulted in staggering numbers of individuals affected by the disease. A haphazard approach to treatment for a problem of this magnitude could easily overburden the healthcare system, particularly in areas of the world with limited resources.

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  • The evolution of trauma care in developed countries around the world has created new and exciting roles for all the personnel involved in the resuscitation and recovery of critically injured patients. The stress on strict roles for the nurse, doctor, paramedic and ancillary staff is now being replaced by a greater emphasis on the ‘team approach’. This acknowledges the interactive nature of the procedures undertaken by the trauma team and the need for close cooperation at all stages of the resuscitation.

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  • In the past two decades, enormous strides have been made in our understanding of the relationships between inflammation, innate immune responses, adaptive immune responses, and degenerative human diseases. The developing information has mostly appeared in specialty journals that have dealt only with isolated aspects of these tightly related fields. As a result, contemporary scientists have had a difficult time finding sources, even in review articles, that provide an integrated picture.

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  • The physician treating the acutely ill febrile patient must be able to recognize infections that require emergent attention. If such infections are not adequately evaluated and treated at initial presentation, the opportunity to alter an adverse outcome may be lost. In this chapter, the clinical presentations of and approach to patients with relatively common infectious disease emergencies are discussed. These infectious processes and their treatments are discussed in detail in other chapters. ...

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  • 20 A Comparison of the Effects of the Latham–Millard POPLA Procedure with a Conservative Treatment Approach on Dental Occlusion and Facial Aesthetics in CUCLP and CBCLP Samuel Berkowitz, Martha Mejia 20.1 Dental Occlusion One of the most widely debated areas in the treatment of cleft lip and palate involves the use of presurgical orthopedics and periosteoplasty with lip adhesion (POPLA) designed by Ralph Latham (orthodontist) and D. Ralph Millard, Jr. (plastic surgeon) [1, 2].

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  • What attracted us to plastic surgery are its tremendous scope and the multitude of approaches for every clinical situation. Yet precisely these aspects of plastic surgery make its study and teaching especially challenging. Although there are several excellent atlases and texts, we have come across few references that are compact, affordable, timely, and focus on the practical, day-to-day practice of plastic surgery.

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  • Obstetrics and gynaecology is a dynamic and rapidly changing speciality. Great advances have been made in prenatal diagnosis, the management of infertility and contraceptive techniques. The introduction of minimally invasive surgical procedures has reduced bed occupancy and analgesic requirements allowing women to return home more rapidly. Service delivery development, required to meet improving NHS standards, has seen the introduction of a new multidisciplinary approach, new roles for midwives and the emergence of the gynaecological nurse practitioner....

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  • This book has been written to enable health care workers to understand the principles of managing an acute medical emergency safely and effectively.To achieve this aim it provides a structured approach to medical emergencies, describing relevant pathophysiology that will also help to explain physical signs and the rationale behind treatment.The first edition of this manual (written by Terry Wardle) has undergone significant modification directed by the working group and also, in particular, candidates from the first MedicALS courses.

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  • Consistent with my long-standing aspiration to become a psychoanalyst, I trained in psychiatry at the Massachusetts Mental Health Center of Harvard Medical School in the early 1960s and completed a residency there. Then I changed direction. I decided not to obtain psychoanalytic training or even to have a clinical practice. Rather, I spent the next 40 years doing biological research—developing a reductionist approach to learning and memory, first in snails and then in mice.

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  • Why do thoracic surgeons need training in decision making? Many of us who have weathered harrowing residencies in surgery feel that, after such experiences, decision making is a natural extension of our selves. While this is no doubt true, correct decision making is something that many of us have yet to master. The impetus to develop a text on evidence-based decision making in thoracic surgery was stimulated by a conference for cardiothoracic surgical trainees developed in 2004 and sponsored by the American College of Chest Physicians....

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  • A definitive summary of novel techniques, this 1st volume in the New Technologies Series details the most current and multidisciplinary approach to new technologies used in general plastic, hand, peripheral nerve, microsurgery, breast, esthetic, and trauma surgery and provides an overview of the most important and clinically relevant plastic surgery research. New surgical images of new surgical approaches are all accompanied with anatomical descriptions.

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  • Since we compiled our first book on pediatric laparoscopy a decade ago, a lot has changed. In the early days, few pediatric surgeons challenged the establishment as they forged ahead, pushing the edges of the envelope before them, into a new area. We had to prove that pediatric laparoscopy offered some benefit to our patients. We had to justify every so-called “new” approach.

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  • Despite the significant decline in heart disease mortaht' rates over the last 25 years, heart failure has remained a significant problem. We are now confronted with large numbers of terminally ill patients for whom conventional therapies for heart failure have been exhausted and for whom repeated hospital visits are necessary. There now is a major thrust towards a management strategy which embraces a comprehensive approach including vigorous preventive measures and earlier surgical interventions.

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  • This book is an outgrowth of the author’s experience teaching a toxicology course for 12 years at West Chester University and his interactions with physicans and laboratory toxicologists for 24 years in the Crozer Keystone Health System. These experiences provided valuable insights into the needs both groups have for an enhanced understanding of toxicology in the laboratory and in the emergency department.

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  • The area of gastrointestinal oncology is an active one. Both clinical research and basic research have come together and changed the diagnostic and treatment protocols for a number of deadly malignancies. A multidisciplinary approach to the diagnosis and treatment appears to be the best paradigm; it allows for each individual medical specialty to apply their knowledge and expertise in an expeditious and effective manner.

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  • The underlying principle in managing diabetes has undergone several important changes over the last two decades. Diabetes was once believed to be a disease with inevitable microvascular and macrovascular complications. Current approaches to management, however, recognize the benefit of maintaining tight glycemic control and addressing associated metabolic disorders.

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  • This compact and concise monograph lays a foundation for the understanding of normal cardiovascular function. Students welcome the book as a practical partner or alternative to a more mechanistically oriented approach or an encyclopedic physiology text. Especially clear explanations, ample illustrations, clinical cases and problems, and chapter-opening learning objectives provide guidance for self-directed learning and help fill the gap in many of today's abbreviated physiology blocks. A focus on well-established cardiovascular principles reflects recent, widely accepted research....

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