(BQ) Part 1 book "Clinical management of overweight and obesity" presents the following contents: Overview of the management of obese patients, diet recommendations, physical activity, therapeutic education, pharmacological management, bariatric surgery.
Twenty years ago in the twenty-first edition of the
Principles and Practice of Medicine, the authors
described what was then the practice for the pharmacologic
therapy of patients with heart failure,
which included digoxin and a diuretic . In addition,
the authors noted that recent studies had
supported the potential use of vasodilators in the
treatment of this population of patients.
In one sense, pharmacology can be considered a “good
news, bad news” scenario. The good news is that
exciting and innovative changes in drug therapy continue
to occur at lightning speed. The bad news is that
it is often difficult for health care practitioners to stay
abreast of this rapidly changing field. Oftentimes,
drug therapies that were considered state-of-the-art
only a few years ago are now outdated and replaced by
more contemporary treatments.
Widely recognised as the best starting point for pharmacology study, the internationally best-selling Medical Pharmacology at a Glance is an ideal companion for all students of the health sciences.
Key principles are supported by coloured schematic diagrams - invaluable as both an introduction to medical pharmacology, and revision in the run-up to pharmacology exams.
In the 4th edition we have distilled the text to a set of fl ow diagrams with
linked tables. Our aim is to provide the doctor caring for an acutely ill patient
with rapid access to key information, including a balanced interpretation of
current national and international guidelines.
We have substantially broadened the scope of the book to cover all problems
in general medicine likely to be encountered in the emergency department.
Integration of the use of echocardiography, which we believe is as
important in acute medicine as ECG interpretation, is a particular feature of
Upper respiratory tract infections and, especially, sinusitis are frequently
encountered in the day-to-day practice of infectious disease specialists, allergists,
pediatricians, otolaryngologists, internists, and family practitioners.
The range of causative agents and available therapies and the constantly
changing spectrum of antibiotic resistance can make it difficult to select
the most appropriate course of treatment.
This chapter describes the background to why it became necessary to regulate the use and supply of drugs, and the ways in which these processes are managed. • Basis for regulation: safety, efficacy, quality, supply • Present medicines regulatory system • Present day requirements • Counterfeit drugs • Appendix: the thalidomide disaster
change the safety information e.g. add new warnings, or contraindications. The quality aspects may also need to be revised as manufacturing practices change. MAH's have strong profit motives for making claims about their drugs.
The last quarter of a century has seen dramatic
developments in the management of cardiovascular
diseases. Besides the pioneering developments in
the medical management of cardiovascular disorders
the field of interventional cardiology has also emerged
as a major discipline with a huge impact on the
clinical management of acute coronary syndrome,
chronic coronary artery disease, congestive heart
failure, and peripheral vascular and valvular diseases.
Hypertension and coronary heart disease (CHD) are of great importance. Hypertension affects above 20% of the total population of the USA with its major impact on those over age 50. CHD is the cause of death in 30% of males and 22% of females in England and Wales. Management requires attention to detail, both clinical and pharmacological. The way drugs act in these diseases is outlined and the drugs are described according to class.
It has been almost a decade since the first edition of Clinical Management of Diabetic
Neuropathy was published. Since then, all societies have seen an explosion in obesity and
diabetes. As a result, there is also an explosion in long-term diabetes complications,
including diabetic neuropathy. Diabetic neuropathy therefore remains a major health
problem that has not only serious consequences for the patient but also carries a significant
financial burden for the health care-providing organizations of every society....
Rational use of haematinic drugs is essential to the correction of anaemia in its various forms. The emergence of haemopoietic growth factors as drugs that stimulate erythroid or myeloid cell lines has opened the way to successful management of other forms of haematological disease. Iron: therapy, acute overdose Vitamin B12 (cobalamins) Folic acid Haemopoietic growth factors Sickle cell anaemia Polycythaemia rubra vera Aplastic anaemia
'colouring matter' of the blood and the 'defective nature of the colouring matter' in anaemia were recognised.
The underlying principle in managing diabetes
has undergone several important changes over the
last two decades. Diabetes was once believed to
be a disease with inevitable microvascular and
macrovascular complications. Current approaches
to management, however, recognize the benefit
of maintaining tight glycemic control and addressing
associated metabolic disorders.
Antiepilepsy drugs: principles of management; withdrawal of therapy; pregnancy; teratogenic effects; epilepsy in children; status epilepticus • Individual drugs: carbamazepine, phenytoin, sodium valproate, lamotrigine, vigabatrin, gabapentin, clonazepam, topiramate, levetiracetam. • Parkinsonism Objectives of therapy Drug therapy; problems of long-term treatment • Other disorders of movement • Tetanus
cortical neurons simultaneously (primary generalised seizure). Bromide (1857) was the first drug to be used for the treatment of epilepsy, but it is now obsolete.
Procedural sedation and analgesia represents one of the great advances in the maturation
of emergencymedicine as a discrete specialtywithinmedicine.Once the exclusive domain
of the anesthesiologist, sedation and painmanagement procedures are nowa routine part
of all emergency department practices.
Emergency Sedation and Pain Management is a comprehensive medical text
addressing emergency sedation and analgesia with specific emphasis on treatment of
the emergency department patient.
Acute-care clinicians are well aware of the alphabetical
“ABC” (airway, breathing, circulation)
directive of resuscitation. This term has been
widely disseminated through programs such as
Advanced Trauma Life Support (ATLS) and Advanced
Cardiac Life Support (ACLS). In fact,
both courses have contributed significantly to
improving awareness of resuscitation priorities
required in managing patients rendered critically
ill from trauma or cardiac events.
Correction of blood lipid abnormalities offers scope for a major impact on cardiovascular disease. Drugs play a significant role and have a variety of modes of action. Dietary and lifestyle adjustment are components of overall risk prevention.
Problems of constipation, diarrhoea and irritable bowel syndrome are common. Infective diarrhoeal diseases are a significant cause of morbidity and mortality worldwide, especially in infants and children.The management of these conditions is reviewed. • Constipation: mode of action and use of drugs • Diarrhoea (drug treatment importance of fluid and electrolyte replacement) • Inflammatory bowel disease • Irritable bowel syndrome
STOOL BULKING AGENTS Dietary fibre comprises the cell walls and supporting structures of vegetables and fruits.
Infection is a major category of human disease and skilled management of antimicrobial drugs is of the first importance.The term chemotherapy is used for the drug treatment of parasitic infections in which the parasites (viruses, bacteria, protozoa, fungi, worms) are destroyed or removed without injuring the hostThe use of the term to cover all drug or synthetic drug therapy needlessly removes a distinction which is convenient to the clinician and has the sanction of long usage.
The field of Pain Medicine has evolved over the last 20 years to include an
increasing array of sophisticated and technologically complex diagnostic and therapeutic
procedures. Concurrent to this advancement has been the development of a
battery of pharmacological options to treat pain, from extended-release formulations
of analgesics to antidepressants and anticonvulsants designed to treat specific types of