Xem 1-20 trên 68 kết quả Phosphorylation state
  • We conducted our audit of compliance in accordance with U.S. generally accepted auditing standards; the standards applicable to financial audits contained in Government Auditing Standards, issued by the Comptroller General of the United States; and OMB Circular A-133, Audits of States, Local Governments, and Non-Profit Organizations.

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  • Almost 75 percent of the elderly (age 65 and over) have at least one chronic illness.3 About 50 percent have at least two chronic illnesses.3 Chronic conditions can lead to severe and immediate disabilities, such as hip fractures and stroke, as well as progressive disability that slowly erodes the ability of elderly people to care for themselves.4 According to AHRQ’s 1996 Medical Expenditure Panel Survey (MEPS),a about 14.3 percent of people age 65 and over—4.5 million elderly Americans—require assistance with bathing, dressing, preparing meals, or shopping.

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  • The information compiled in this report reflects evidence collected from WHP policies in high-income countries, primarily within the European and North American regions. The scarcity of information and case studies from low- and middle-income countries was highlighted as an important gap in the current knowledge that needs to be addressed. Despite the limits of the available evidence, all stakeholders are encouraged to develop and implement WHP policies and programmes tackling unhealthy diets and physical inactivity....

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  • In recent years, the Court invalidated two con- gressional statutes that attempted to regulate non- economic activities. In United States v. Lopez (1995), it struck down the Gun-Free School Zones Act, which attempted to reach the activity of possessing a gun within a thousand feet of a school. In United States v. Morrison (2000), it invalidated part of the Violence Against Women Act, which regulated gen- der-motivated violence.

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  • Within the Latin American context, worker remittances are becoming increasingly relevant to the economies of many countries. In 2003, Lat in America received more than $38 billion in remittances from Canada, Europe, Japan, Latin America itself and the United States. The table 4 shows the total remittances sent to selected countries in Latin America and the Caribbean in 2003. The table also shows remittances as a percentage of GDP and exports.

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  • The FCC Office of Plans and Policy's Working Paper Series presents staff analysis and research in various states. These papers are intended to stimulate discussion and critical comment within the FCC, as well as outside the agency, on issues in telecommunications policy. Titles may include preliminary work and progress reports, as well as completed research. The analyses and conclusions in the Working Paper Series are those of the authors and do not necessarily reflect the view of other members of the Office of Plans and Policy, other Commission Staff, or the Commission itself.

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  • To accurately estimate energy savings attributable to the ENERGY STAR program, and target future efforts, current data are needed on the extent to which each type of office equipment is turned off or successfully enters low power mode when idle. Combined with measurements of the energy used in each power state, we can estimate typical unit energy consumption (UEC), which, combined with number of units currently in use, provides an estimate of total energy use, and program savings (Webber, Brown et al. 2002). In our ongoing technical support of ...

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  • With the increase of wealth and commerce in Europe, private bankers established themselves in all the principal cities and towns. They re- ceived money on deposit; they managed the money affairs of states and individuals; they lent money to such borrowers as could give the neces- sary security; and they bought and sold bills of exchange, bullion, and coin. The English bankers were not slow in perceiving the profits which the Bank of England derived from the circulation of its notes. They imitated its example.

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  • Multisite protein phosphorylation is a common regulatory mechanism in cell signaling, and dramatically increases the possibilities for protein– protein interactions, conformational regulation, and phosphorylation path-ways. However, there is at present no comprehensive picture of how these factors shape the response of a protein’s phosphorylation state to changes in kinase and phosphatase activities.

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  • In the following decades, the insurance regulators of the 48 (and eventually 50) states followed a similar path. State insurance regulators established minimum capital requirements that were geared to the ratings on the bonds in which the insurance companies invested—the ratings, of course, coming from the same small group of rating agencies. Once again, an important set of regulators had delegated their safety decisions to the credit rating agencies. In the 1970s, federal pension regulators pursued a similar strategy.

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  • The logframe should thus not be seen as simply a set of mechanistic procedures, but as an aid to thinking. The logframe must also be seen as a dynamic tool, which should be re-assessed and revised as the project itself develops and circumstances change. It should be used to provide structure and purpose to project planning and budgeting without being perceived as an inflexible and constraining blueprint.

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  • One of the key areas the Board wants to pursue in the coming years continues to be Clinical Skills Assessment. This testing procedure would measure the clinical skills not only of new doctors, but of physicians coming into the state from elsewhere, who have been away from practice for an extended period or who may have had multiple medical malpractice payments or other problems. In 2004, the National Medical Board of Examiners began requiring all new physicians to pass a clinical skills exam. But there are only five locations nationwide where such physicians may take the test.

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  • The marketing mix concept is one of the core concepts of marketing theory. However, in recent years, the popular version of this concept McCarthy’s (1964) 4Ps (product, price, promotion and place) has increasingly come under attack with the result that different marketing mixes have been put forward for different marketing contexts. While numerous modifications to the 4Ps framework have been proposed (see for example Kotler, 1986; Mindak and Fine, 1981; Nickels and Jolson, 1976; Waterschoot and Bulte. 1992) the most concerted criticism has come from the services marketing area.

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  • The main objective of the Citizen's Charter is to improve the quality of public services. This is done by letting people know the mandate of the Corporation, how one can get in touch with its officials, what to expect by way of services and how to seek a remedy if something goes wrong. The Citizen’s Charter does not by itself create new legal rights, but it surely helps in enforcing existing rights.

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  • As crop prices increase, the value of the crops being insured increases, which results in higher crop insurance premiums and premium subsidies. For example, the prices of major crops were substantially higher in 2011 than in 2006, and premium subsidies in 2011 (about $7.4 billion) were substantially higher than in 2006 (about $2.7 billion). USDA forecasts that the prices of major crops—corn, cotton, soybeans, and wheat—will continue to be substantially higher than 2006 prices through 2016. Administrative expense subsidies also increased because of higher crop prices.

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  • Different PHI functions give rise to specific policy challenges. Primary PHI markets often create access-related challenges, especially for high-risk and vulnerable groups, where they represent the sole form of cover for some population groups.15 Where public and private delivery systems are linked to different funding sources, as in systems with duplicate private health insurance, differences in access to care, choice levels and utilisation patterns occur between individuals with and without private insurance.

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  • Ooplasmic transfer involves egg retrieval from the woman undergoing IVF and another woman donating ooplasm (the cytoplasm of an egg cell: the material outside the nucleus). The egg is then fertilized with sperm and implanted into the woman intending to become pregnant. The resulting child has DNA from both women because of the mitochondrial DNA present in the ooplasm of the donor, as well as DNA from the sperm provider (partner or donor), and therefore has three genetic parents. It had been used for women whose infertility seemed to stem from the ooplasm in their eggs.

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  • African countries have a choice between establishing an agricultural sector founded on broad-based ownership of medium-size farms (much larger than those currently operated and expanding over time) or a dual structure where a few mega farms coexist with many small producers. Given the long-term impacts associated with such choices, clear elaboration of the issues in an informed public debate about the development paths open to a country is needed.

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  • Vincent Cogliano reported holding stocks, bonds, stock options or other securi- ties in a commercial entity with an interest related to air pollution. He also re- ported having held office or position, paid or unpaid, where he may have been expected to represent interests or defend a position related to the subject of air pollution. David Eastmond reported having received research support from a commercial entity or other organization with an interest related to the subject of air pollution.

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  • In this scene building towards the climax of the film, the director is using the technique of cross- cutting to build up suspense, create narrative tension and to wrong foot the audience.. Will the FBI get to the house of the serial killer in time to save the woman whom he has imprisoned in the basement? At this point in the movie, the FBI believe that they have tracked down the address of the serial killer while the lead character, Clarice Starling (played by Jodie Foster) is searching elsewhere. Because we are so used to this type of dramatic scene...

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