Population genetics

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  • Population geneticists study the genetic composition and variability of natural populations as well as the theories that explain this variability in terms of natural selection, mutation, recombination, genetic drift and gene flow. Population genetics was first developed among eukaryotes in an attempt to reconcile Darwin’s theory of evolution by natural selection and Mendelian genetics. When Darwin postulated that natural selection is the main force of evolutionary change, a great controversy was created.

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  • When it comes to advocating animal conservation, it is difficult to be convincing without becoming alarmist. The fact is, time is running out for many of the world’s animal species. Habitat loss, introduced species, overexploitation and pollution, all caused by human activities, combine with stochastic factors to place ever-increasing pressure on natural populations (Primack 2002).

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  • The epidemiology of infectious diseases is one of the great triumphs of applied ecology. In particular, the public health importance of parasites has lead to a large literature, exploring their impact on the population dynamics, population genetics and evolutionary biology of human populations. An important milestone was the Dahlem Conference on population biology of infectious diseases, held in 1981. The resulting book (Anderson and May 1982) lucidly summarised the contemporary state of parasite ecology and epidemiology.

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  • The theory and practice of molecular ecology draw on a number of subjects, particularly genetics, ecology and evolutionary biology. Although the foundations of molecular ecology are not particularly new, it did not emerge until the 1980s as the discipline that we now recognize. Since that time the growth of molecular ecology has been explosive, in part because molecular data are becoming increasingly accessible and also because it is, by its very nature, a collaborative discipline.

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  • In the last decade the progress of molecular biology has made a strong influence on the theoretical framework of population genetics and evolution. Introduction of molecular techniques in this area has resulted in many new discoveries. As a result, a new interdisciplinary science, which may be called 'Molecular Population Genetics and Evolution', has emerged. In this book I have attempted to discuss the development and outline of this science. In recent years a large number of papers have been published on this subject.

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  • Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Assessing population genetic structure via the maximisation of genetic distance

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  • which allows users to download, copy and build upon published articles even for commercial purposes, as long as the author and publisher are properly credited, which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech, authors have the right to republish it, in whole or part, in any publication of which they are the author, and to make other personal use of the work. Any republication,

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  • Population Genetics In population genetics, the focus changes from alterations in an individual's genome to the distribution pattern of different genotypes in the population. In a case where there are only two alleles, A and a, the frequency of the genotypes will be p2 + 2pq + q2 = 1, with p2 corresponding to the frequency of AA, 2pq to the frequency of Aa, and q2 to aa. When the frequency of an allele is known, the frequency of the genotype can be calculated. Alternatively, one can determine an allele frequency, if the genotype frequency has been determined. Allele frequencies vary...

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  • Tuyển tập các báo cáo nghiên cứu về lâm nghiệp được đăng trên tạp chí lâm nghiệp Original article đề tài: Population genetics of Norway spruce (Picea abies Karst.) at regional scale: sensitivity of different microsatellite motif classes in detecting differentiation...

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  • What happened after the initial global spread of pandemic human influenza virus A (H1N1)? A population genetics approach

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  • We have endeavoured to make A Primer of Conservation Genetics as com- This book is intended to provide a brief accessible introduction to the general principles of conservation genetics prehensible as possible to a broad range of readers. It is suitable for those undertaking introductory genetics courses at university, for students undertaking conservation biology courses and even for motivated first-year biology students who have completed lectures on basic Mendelian genetics and introductory population genetics (allele frequencies and Hardy--Weinberg equilibrium).

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài:Population genetics of cancer cell clones: possible implications of cancer stem cells...

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Population genetics and the Cretaceous extinction

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Population genetics of the metabolically related Adh, Gpdh and Tpi polymorphisms in Drosophila melanogaster : II. Temporal and Spatial Variation in an Orchard Population Karen M. NIELSEN A.A. HOFFMANN S.W. McKECHNIE

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Population genetics of French brown trout (Salmo trutta L): large geographical differentiation of wild populations and high similarity of domesticated stocks

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  • This chapter students will be able to: Recognize that natural selection is the correct mechanism for explain evolution; understand the importance of and identify sources of genetic variation; know how to solve various problems associated with Hardy-Weinberg equilibrium; list the five factors, and state an example of each, that affect Hardy-Weinberg equilibrium and understand how each can produce evolutionary changes in a population experiencing any one of the five;...

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  • Population Screening Mass genetic screening programs require tests of high enough sensitivity and specificity to be cost-effective. An effective screening program should fulfill the following criteria: that the tested disorder is prevalent and serious; that it can be influenced presymptomatically through lifestyle changes, screening, or medications; and that identification of risk does not result in undue discrimination or harm.

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  • Since the 1930s, the USDA (U.S. Department of Agriculture) Forest Service’s International Institute of Tropical Forestry (the Institute) has studied mahogany and its management. In the 1960s, F.B. Lamb, the author of the classic book on mahogany (1966), was an Institute collaborator. Before gene flow and genetic erosion became popular terms, my predecessor Frank Wadsworth established a gene bank at the Luquillo Experimental Forest.

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  • Molecular analysis is generally more informative if testing is initiated in a symptomatic family member, since the identification of a mutation can direct the testing of other at-risk family members (whether they are symptomatic or not). In the absence of additional familial or environmental risk factors, individuals who test negative for the mutation found in the affected family member can be informed that they are at general population risk for that particular disease. Furthermore, they can be reassured that they are not at risk for passing on the mutation to their children.

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  • Therapeutic Interventions Based on Genetic Risk for Disease Specific treatments are now available for an increasing number of genetic disorders, whether identified through population-based screening or directed testing (Table 64-2). Although the strategies for therapeutic interventions are best developed for childhood hereditary metabolic diseases, these principles are making their way into the diagnosis and management of adult-onset disorders. Hereditary hemochromatosis illustrates many of the issues raised by the availability of genetic screening in the adult population.

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