Xem 1-20 trên 23 kết quả Potentially malignant
  • Abstract Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteinases that are capable of cleaving all extra cellular matrix (ECM) substrates. Degradation of matrix is a key event in progression, invasion and metastasis of potentially malignant and malignant lesions of the head and neck. It might have an important polymorphic association at the promoter regions of several MMPs such as MMP-1 (-1607 1G/2G), MMP-2 (-1306 C/T), MMP-3 (-1171 5A/6A), MMP-9 (-1562 C/T) and TIMP-2 (-418 G/C or C/C)....

    pdf13p toshiba23 18-11-2011 42 2   Download

  • The PSA criteria used to recommend a diagnostic prostate biopsy have evolved over time. The goal is to increase the sensitivity of the test for younger men more likely to die of the disease and to reduce the frequency of detecting cancers of low malignant potential in elderly men more likely to die of other causes. Age-specific reference ranges reduce the upper limit of normal for younger men and increase it for older men. Different thresholds alter the sensitivity and specificity of detection. The threshold for performance of a biopsy was 4.0 ng/mL, which has been reduced to 2.6...

    pdf5p konheokonmummim 03-12-2010 42 4   Download

  • The increasing number of chromosomal rearrangements involving the humanMLLgene, in combination with differences in clinical behavior and outcome for MLL-rearranged leukemia patients, makes it necessary to reflect on the cancer mechanism and to discuss potential therapeutic strate-gies. To date, 64 different translocations have been identified at the molecular level.

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  • The new toolkit focuses on relapse prevention, risks of secondhand smoke exposure and the health benefits of quitting smoking for mother and infant. It also emphasizes the potential and underlying issues related to relapse including postpartum depression, stress and miscarriage. An appendix for counselors to use as a reference tool during counseling sessions is also included in the toolkit.

    pdf24p connicquy 20-12-2012 26 8   Download

  • Pathology of the Head and Neck is an easy sounding title for a complex subject matter. This title stands for an accumulation of diverse diseases occurring in different organs whose relationship to each other consists in the fact that they are located between the base of the skull and the thoracic aperture.

    pdf334p maket1311 16-10-2012 44 7   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases

    pdf11p dauphong6 04-01-2012 25 6   Download

  • There has been only modest improvement in the productivity of indigenous cows, cross- breds or buffaloes over the last two decades in India (Table 1). The average daily milk production data at 6.52 kg for crossbreds, 2.10 kg for indigenous cattle and 4.44 kg for buffaloes (NSSO, 2007) suggests that the productivity of these animals is far below their genetic potential.

    pdf109p conduongdinhmenh 07-05-2013 21 5   Download

  • At the end of 1996 the first prepaid cards were issued in Germany by the German banking sector (ZKA-GeldKarte-System) and tested in a pilot project. Since the successful test phase the number of prepaid GeldKarte cards has increased to 67.3 million. There are cards linked to accounts, where the GeldKarte chip is integrated into an ec card, as well as cards not linked to an account (“white cards”), which have only an electronic purse function.

    pdf196p enterroi 02-02-2013 21 4   Download

  • Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học đề tài : A novel multiplex assay combining autoantibodies plus PSA has potential implications for classification of prostate cancer from non-malignant cases

    pdf11p dauphong8 14-01-2012 18 3   Download

  • The tactile examination of the breast is best performed with the patient re- cumbent with her arm raised above her head. A small pillow under her upper back can further distribute the breast tissue over the chest wall. Palpation is performed using the base of the fingertips in small circular motions with vari- able depth. Recall that breast tissue extends beyond the region usually defined by a bra cup.

    pdf8p connicquy 20-12-2012 16 3   Download

  • Tumor markers are secreted, released, or leaked into the interstitial fluids, and thus into the lymph, and finally (or directly) into the bloodstream, where they become detectable in serum samples. To be able to enter the bloodstream directly, larger molecules, often proteins, are cleaved into truncated forms or fragments, which are sometimes specific to the protease micro-environment of the tumor. Tumor markers can be associated with patient diagnosis, prognosis, clinical management, and follow-up.

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  • It is becoming increasingly clear that signals generated in tumor microenvi-ronments are crucial to tumor cell behavior, such as survival, progression and metastasis. The establishment of these malignant behaviors requires that tumor cells acquire novel adhesion and migration properties to detach from their original sites and to localize to distant organs.

    pdf15p cosis54 05-01-2013 15 3   Download

  • In Southeast Asia there have been found a lot of rubber-bearing plants. Most of them are members of the one family, Apocynaceae, but there are also some important species from other families, like Ficus elastica Roxb. and Bleekrodea tonkinensis Dub. & Eber., which both belongs to the family Moraceae. The first seeds for the cultivation of the rubber were sent to Asia, Sri Lanka, in 1876, but these first attempts to grow the rubber trees (Hevea brasiliensis Muell. Arg.) were not successful. It was not until 1877 when 22 rubber trees were plated in Singapore. From...

    pdf121p thieubaotrang 23-04-2013 19 3   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Retroperitoneal smooth muscle tumor of uncertain malignant potential after hysterectomy: a case report...

    pdf6p thulanh25 07-12-2011 22 2   Download

  • The third meeting of the Internet Governance Forum officially opened today in Hyderabad, India, focussing on the overall issue of "Internet for all". Participants from government, the private sector, civil society and the Internet community are gathering for the next four days to share information, experiences and best practices and to explore how the Internet can be used to its full potential for the benefit of all while combating its use for harmful purposes.

    pdf5p doiroimavanchuadc 06-02-2013 14 2   Download

  • This manual applies equally to conventionally housed birds and free-range operations. It is recognised that free-range birds will have some exposure to wild birds. However, in these environments measures should be taken to minimise the congregation of waterfowl and the impacts of wild birds generally, and these measures should be documented. While footbaths are not appropriate for a free range paddock, a system should be implemented to monitor and prevent any potential hazardous organic material or litter entering free range paddocks and these measures should be documented.

    pdf36p loginnhanh 22-04-2013 22 1   Download

  • Combined methods have led to further refinements with, for example, high visuospatial resolution afforded by MRI combined with metabolic information from the lesion site (measured with 18F-fluorodeoxyglucose positron emission tomography; FDG-PET) to indicate location and malignancy of gliomas, which in turn informs radiosurgical targeting. Kapsalaki et al. (Chapter 7) consider MRS spectroscopic profiles for differentiation among ring enhancing lesions including high grade gliomas, abscesses and post-radiation necrosis.

    pdf224p wqwqwqwqwq 21-07-2012 57 10   Download

  • The potential value of artificial neural networks (ANNs) as a predictor of malignancy has now been widely recognised. The concept of ANNs dates back to the early part of the 20th century; however, their latest resurrection started in earnest in the 1980s when they were applied to many problems in the areas of pattern recognition, control, and optimisation.

    pdf212p echbuon 02-11-2012 27 5   Download

  • Cancer Chemoprevention Chemoprevention involves the use of specific natural or synthetic chemical agents to reverse, suppress, or prevent carcinogenesis before the development of invasive malignancy. Cancer develops through an accumulation of genetic and epigenetic changes that are potential points of intervention to prevent cancer. The initial changes are termed initiation. The alteration can be inherited or acquired through the action of physical, infectious, or chemical carcinogens.

    pdf6p konheokonmummim 03-12-2010 42 3   Download

  • Mucositis Irritation and inflammation of the mucous membranes particularly afflicting the oral and anal mucosa, but potentially involving the gastrointestinal tract, may accompany cytotoxic chemotherapy. Mucositis is due to damage to the proliferating cells at the base of the mucosal squamous epithelia or in the intestinal crypts. Topical therapies, including anesthetics and barrier-creating preparations, may provide symptomatic relief in mild cases.

    pdf4p konheokonmummim 03-12-2010 25 3   Download

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