Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về y học đề tài: The limited utility of electrocardiography variables used to predict arrhythmia in psychotropic drug overdose...
Advances in drug treatment have revolutionised the practice of psychiatry over the past six decades. Drugs provide a degree of stability and control in the lives of those suffering from schizophrenia, a chronic debilitating illness with impact so profound that it accounts for 2-3% of UK national health spending. Similarly, the impact of medication in alleviating the burden on individuals, their families and society of depression, which has a lifetime prevalence of up to I in 6 of the population, is substantial. ...
The reality is more complex since the receptor binding profile of clozapine and the newer atypical antipsychotic agents suggests that D2-receptor blockade is not essential for antipsychotic effect. The atypical drugs act on numerous receptors and modulate several interacting transmitter systems. Clozapine is a highly effective antipsychotic. It has little affinity for the D2-receptor compared with classical drugs but binds more avidly to other dopamine subtypes (e.g. D1, D3 and D4). It blocks muscarinic acetylcholine receptors, as do certain classical agents (e.g.
Benzodiazepines show antianxiety, hypnotic, anticonvulsant and muscle-relaxant effects. This group of drugs has wide safety dose ranges; it means that the ratio of the LD50 to the ED50 (therapeutic index) is high. Because of its safety, benzodiazepines are being widely used in the world. Some of benzodiazepines are also being abused or used for so-called “drug facilitated sexual assault”, and thus they are under the control of the Narcotics and Psychotropics Control Law; in Japan, triazolam abuse has become one of the serious social problems.
Deliberate and accidental self-poisoning Principles of treatment Poison-specific measures General measures Specific poisonings: cyanide, methanol, ethylene glycol, hydrocarbons, volatile solvents, heavy metals, herbicides and pesticides, biological substances (overdose of medicinal drugs is dealt with under individual agents) Incapacitating agents: drugs used for torture
drugs, and psychotropic drugs is increasing. Repeated episodes are not rare.1 Prescribed drugs are used in over 75% of episodes but teenagers tend to favour nonprescribed analgesics available by direct sale, e.g.
This book is the long-anticipated sequel to the first edition of Psychological Aspects
of Women’s Health Care written almost a decade ago. In this edition, the authors
continue the tradition of writing and speaking plainly about the
fascinating, and at times baffling, relationships between women patients and
their obstetrician and gynecologist physicians. As the authors note, the field
has changed dramatically since the first volume was published.
The global burden of neuropsychiatric disorders is substantial. When measured by years lived
with disability and years lost due to premature death in disability-adjusted life years (DALYs),
psychiatric and neurological conditions accounted for 13% of the global burden of disease in
2002 (WHO, 2004).
Despite the huge burden of mental illness, few human and financial resources are directed
towards mental health care. Mental health spending in many countries of the world is less than
1% of the health budget, and the number of mental health professionals is grossly inadequate