Radiotracer

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  • (BQ) Part 1 book "Principles and practice of PET and PET/CT" presents the following contents: Production of radionuclides for PET, PET physics and PET instrumentation, radiotracer chemistry, data analysis and image processing, fundamentals of CT in PET/CT, standardized uptake values, image fusion, oncologic applications,...

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  • Molecular cloning has identified eight metabotropic glutamate receptor (mGluR) subtypes, each with distinct patterns of expression. However, the characteristic roles of these different mGluRs in physiological processes are not well understood. Identification of subtype-specific compounds may potentially act as therapeutic agents for the treatment of a wide range of conditions (including progressive brain disease, epilepsy and cerebral ischemia) all of which are associated with abnormal mGLuR activation.

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  • The field of molecular imaging/nuclear medicine continues to build excitement for the medical community as a whole. To be able to visualize fundamental molecular and biochemical processes in patients in a meaningful way has truly become reality. Of all the available molecular probes and tools it is clear that FDG with PET-CT is one of the true clinical success stories. Very few would have been able to predict the eventual impact of a simple glucose analog as a marker for imaging cancer, hibernating myocardium, Alzheimer’s disease, epilepsy and many other important disease processes....

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  • There have been several significant advances innuclearmedicine since the publication of the second edition of Practical NuclearMedicine. The last seven years have seen great strides in instrumentation, including new coincidence detectors, the development of a wider variety of crystals, and the advent of combined anatomical/functional imaging devices, including PET/CT and SPECT/CT. PET imaging with 18F-FDG has become a mainstay of many clinical settings, and other radiotracers are finding theirway into the rapidly expanding field of oncologic PET.

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