Xem 1-20 trên 100 kết quả Rare disease
  • Dr. Sharon Rounds, the editor for this series who invited us to write a book on rare lung diseases, developed the idea after attending the 2004 Lymphangioleiomyomatosis (LAM) Foundation annual research meeting. She was a keynote speaker at that event (during her tenure as the president of the American Thoracic Society) and was witness to the power of patient advocacy and the mission-based scientific effort that had brought this rare disease of women from obscurity to clinical trials with targeted molecular therapies in under a decade.

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  • Tuyển tập các báo cáo nghiên cứu về bệnh thú y được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành thú y đề tài: Sampling to Detect Rare Diseases...

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  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A rare disease...

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  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Shared communication processes within healthcare teams for rare diseases and their influence on healthcare professionals’ innovative behavior and patient satisfaction

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  • Dental Care of Medically Complex Patients Routine dental care (e.g., extraction, scaling and cleaning, tooth restoration, and root canal) is remarkably safe. The most common concerns regarding care of dental patients with medical disease are fear of excessive bleeding for patients on anticoagulants, infection of the heart valves and prosthetic devices from hematogenous seeding of oral flora, and cardiovascular complications resulting from vasopressors used with local anesthetics during dental treatment. Experience confirms that the risks of any of these complications are very low.

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  • Diseases of the Oral Mucosa Infection Most oral mucosal diseases involve microorganisms (Table 32-1). Table 32-1 Vesicular, Bullous, or Ulcerative Lesions of the Oral Mucosa Condition Usual Location Clinical Features Course Viral Diseases Primary acute Lip and oral Labial Heals that spontaneously in 10– days.

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  • Becoming less common. Poikiloderma is a term used to describe a patch of skin with (1) reticulated hypo- and hyperpigmentation, (2) wrinkling secondary to epidermal atrophy, and (3) telangiectasias. Poikiloderma does not imply a single disease entity—although becoming less common, it is seen in skin damaged by ionizing radiation as well as in patients with autoimmune connective tissue diseases, primarily dermatomyositis (DM), and rare genodermatoses (e.g., Kindler syndrome). In scleroderma, the dilated blood vessels have a unique configuration and are known as mat telangiectasias.

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  • Pathology The noninvasive proliferation of epithelial cells within ducts is termed prostatic intraepithelial neoplasia. PIN is a precursor of cancer, but not all PIN lesions develop into invasive cancers. Of the cancers identified, 95% are adenocarcinomas; the remainder are squamous or transitional cell tumors or, rarely, carcinosarcomas. Metastases to the prostate are rare, but in some cases colon cancers or transitional cell tumors of the bladder invade the gland by direct extension.

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  • Harrison's Internal Medicine Chapter 103.

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  • The microbiology laboratory must be an ally in the diagnostic endeavor. Astute laboratory personnel will suggest optimal culture and transport conditions or alternative tests to facilitate diagnosis. If informed about specific potential pathogens, an alert laboratory staff will allow sufficient time for these organisms to become evident in culture, even when the organisms are present in small numbers or are slow-growing.

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  • Sick! Diseases and Disorders, Injuries and Infections presents the latest information on 140 wide-ranging illnesses, disorders, and injuries. Included are entries on familiar medical problems readers might encounter in daily life, such as acne, asthma, chickenpox, cancer, and learning disorders. Some rare and fascinating illnesses are covered as well, such as smallpox, hantaviruses, and Creutzfeld Jakob disease (also known as mad cow disease). Entries are arranged alphabetically across the four-volume set and generally range from three to eight pages in length.

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  • Pemphigus Foliaceus Pemphigus foliaceus (PF) is distinguished from PV by several features. In PF, acantholytic blisters are located high within the epidermis, usually just beneath the stratum corneum. Hence PF is a more superficial blistering disease than PV. The distribution of lesions in the two disorders is much the same, except that in PF mucous membranes are almost always spared. Patients with PF rarely demonstrate intact blisters but rather exhibit shallow erosions associated with erythema, scale, and crust formation.

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  • How variations in genes contribute to variations in disease risk has been a subject of study for more than 100 years (IOM, 2006). Until fairly recently research focused on single genes that give rise to rare genetic diseases such as cystic fibrosis or Huntington’s disease.

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  • Pemphigoid Gestationis Pemphigoid gestationis (PG), also known as herpes gestationis, is a rare, nonviral, subepidermal blistering disease of pregnancy and the puerperium. PG may begin during any trimester of pregnancy or present shortly after delivery. Lesions are usually distributed over the abdomen, trunk, and extremities; mucous membrane lesions are rare. Skin lesions in these patients may be quite polymorphic and consist of erythematous urticarial papules and plaques, vesiculopapules, and/or frank bullae. Lesions are almost always very pruritic.

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  • Chronic Idiopathic Myelofibrosis: Treatment No specific therapy exists for chronic IMF. Anemia may be due to gastrointestinal blood loss and exacerbated by folic acid deficiency, and in rare instances, pyridoxine therapy has been effective. However, anemia is more often due to ineffective erythropoiesis uncompensated by extramedullary hematopoiesis in the spleen and liver. Neither recombinant erythropoietin nor androgens, such as Danazol, have proved consistently effective as therapy for anemia.

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  • Vasculitis, an inflammation of blood vessels, can be idiopathic or secondary to other conditions. Infections may also mimic idiopathic vasculitis, and the differential diagnosis is of paramount importance for the practicing physician. Vasculitides are not rare diseases. In fact, some vasculitides, such as giant cell arteritis, cutaneous vasculitis, and ANCA-associated vasculitis are relatively common in everyday practice. Vasculitis may rapidly lead to organ failure, and put patient's life in danger....

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  • For cell-based bone tissue engineering, various tissues derived cells are utilized since osteogenic cells can be harvested from bone marrow, periosteum, and adipose tissue, though recent studies indicate that bone marrow stromal cells (BMSCs, bone marrow derived multipotent mesenchymal stromal cells, or mesenchymal stem cells) are the most reliable cell source because of their superior osteogenic ability (Hayashi et al., 2008). However, it is difficult to obtain adequate numbers of transplantable BMSCs from bone marrow aspirates, as they are rare in the bone marrow (less than 0.

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  • In general, the best beers at a competition should be assigned scores in the 40+ range, with real evaluations of the beer identifying some characteristics of the beer that make it non-perfect. A beer receiving a perfect score of 50 must indeed be perfect; it must have absolutely no flaws, exemplify the style as well as or better than the best commercial examples, be perfectly brewery-fresh, and be well- handled and presented. These conditions might not all be under the brewer’s control, so achieving a perfect beer at the point of presentation to judges is extremely rare. ...

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  • Asmentioned in the introduction, the information associatedwith an event is represented by a data structure called a notification.We refer to the datamodel or encoding schema of notifications as the event notification model or simply event model. Most existing event notification services adopt a simple record- like structure for notifications, while some more recent frameworks define an object-oriented model (e.g., the Java™ Distributed Event Specification [Sun Microsystems 1998] and the CORBA Notification Service [Object Management Group 1998b]).

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  • Hormone resistance syndromes are typically thought of as rare, usually genetic, disorders with a severe but relatively stereotyped clinical and biochemical profile. While there are syndromes of severe insulin resistance that conform to this description, defective insulin action is of much more pervasive biomedical importance. Even moderate degrees of insulin resistance are closely linked to a range of common diseases, including Type 2 diabetes, polycystic ovary syndrome, obesity and hypertension....

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