Regulatory factors

Xem 1-20 trên 103 kết quả Regulatory factors
  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Role of cellular caspases, nuclear factor-kappa B and interferon regulatory factors in Bluetongue virus infection and cell fate

    pdf16p dauphong1 21-12-2011 23 3   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway

    pdf50p panasonic09 12-01-2012 22 3   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Replication of the genetic effects of IFN regulatory factor 5 (IRF5) on systemic lupus erythematosus in a Korean population...

    pdf5p thulanh13 15-10-2011 21 2   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells...

    pdf13p thulanh14 19-10-2011 18 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells

    pdf12p panasonic09 12-01-2012 19 2   Download

  • Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice

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  • Theinterferon-bpromoter has been studied extensively as a model system for combinatorial transcriptional regulation. Invirus-infectedcells the transcription factorsATF-2, c-Jun, interferon regulatory factor (IRF)-3, IRF-7andNF-jB, and the coactivators p300/CBP play critical roles in the activa-tion of this and other promoters. It remains unclear, how-ever, why most other combinations of AP-1, IRF and Rel proteins fail to activate theinterferon-bgene. Here we have explored how different IRFs may cooperate with other fac-tors to activate transcription....

    pdf11p awards 05-04-2013 10 2   Download

  • Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài:Identification of novel regulatory factor X (RFX) target genes by...

    pdf21p coxanh_8 05-11-2011 21 1   Download

  • The innate antiviral response requires the induction of genes and proteins with activities that limit virus replication. Among these, the well-character-ized interferon b (IFNB) gene is regulated through the cooperation of AP-1, NF-jB and interferon regulatory factor 3 (IRF-3) transcription fac-tors. Using a constitutively active form of IRF-3, IRF-3 5D, we showed previously that IRF-3 also regulates an IFN-independent antiviral response through the direct induction of IFN-stimulated genes.

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  • A novel geneZC3H12A, encoding MCP-1-induced protein 1 (MCPIP), was recently identified in human peripheral blood monocytes treated with monocyte chemotactic protein 1 (MCP-1) and in human monocyte-derived macrophages stimulated with interleukin (IL)-1b. These experiments revealed that the gene undergoes rapid and potent transcription induction upon stimulation with proinflammatory molecules, such as MCP-1, IL-1b, tumour necrosis factor aand lipopolysaccharide.

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  • The c-jungene encodes the protein Jun, a component of the essential transcription factor, AP1. Jun/AP-1 occupies a central position in signal transduction pathways as it is responsible for the induction of a number of genes in response to growth promoters. However, the exact mecha-nisms leading to an enhanced expression of the c-jun gene itself during proliferation, differentiation, cell growth and development are not fully understood. Cell culture studies have given some insight in the mechanisms involved in the up-regulation of c-jun expression by UV irradiation and phorbol esters. ...

    pdf9p tumor12 20-04-2013 12 1   Download

  • Virus infection results in the activation of a set of cellular genes involved in host antiviral defense. IRF-3 has been identifiedas a critical transcription factor in this process. The activationmechanismof IRF-3 is not fully elucidated,yet it involves a conformational change triggered by the virus-dependent phosphorylation of its C-terminus. This con-formational change leads to nuclear accumulation,DNA binding and transcriptional transactivation.

    pdf10p tumor12 22-04-2013 11 1   Download

  • Developing countries’ markets depend extensively (technically and financially) on international services. Reasons for this include (among others) structural, financial and technical constraints, including the small size of markets, under-capitalization of insurance companies and insufficient experience and know-how. Usually, insurance industries there also have a shortage of skilled personnel.

    pdf446p thangbienthai 27-11-2012 34 11   Download

  • It is difficult to discern exposures from institutions’ reported credit market posi- tions. Indeed, common data sources such as annual reports and regulatory filings record accounting measures on a large and diverse number of credit market instruments. Ac- counting measures are not necessarily comparable across positions. For example, the economic value of two loans with the same book value but different maturities will react quite differently to changes in interest rates. At the same time, many instruments are close substitutes and thus entail essentially the same market risk.

    pdf101p taisaovanchuavo 23-01-2013 31 9   Download

  • In this vein UNCTADs contribution will continue to focus on: the benefits and challenges arising from international trade in insurance services, regulatory challenges arising from domestic implementation as well as in relation to the GATS, measures to overcome supply side constraints and build domestic capacity in the insurance sector, the role of the Government both as a regulator and a provider of insurance services, likely impacts of emerging global and technological trends in the insurance sector and in relation to the GATS assisting developing countries in their ongoing and evolv...

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  • The dehesa is both a resilient and a fragile system; its resilience derives from the perseverance of its operators, and its fragility is its susceptibility to unfavourable economic factors that influence its profitability (Siebold, 2009). Livestock grazing is an integral management component of a dehesa and undergirds the conservation function of the system. The livestock component, including cattle, accounts for the largest fraction of revenue from the dehesa.

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  • At the end of a day and a half of presentations and discussion, participants concluded that, while more research is needed, there are immediate opportunities to mediate the growing health risks associated with poor eating and physical inactivity. These areas suggest both voluntary and regulatory strategies that focus on strengthening industry accountability, while changing the food and physical activity environment and promoting healthier behaviors.

    pdf49p dangsuynghi 15-03-2013 22 6   Download

  • The Department of Energy's Office of Environmental Management (DOE-EM) is responsible for cleaning up radioactive waste and environmental contamination resulting from five decades of nuclear weapons production and testing. A major focus of this program involves the retrieval, processing, and immobilization of waste into stable, solid waste forms for disposal. This report, which was requested by DOE-EM, examines requirements for waste form technology and performance in the cleanup program.

    pdf271p camnhung_1 14-12-2012 27 5   Download

  • Tham khảo tài liệu 'báo cáo sinh học: " research article uncovering transcriptional regulatory networks by sparse bayesian factor model"', khoa học tự nhiên phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

    pdf18p dauphong15 16-02-2012 34 4   Download

  • Managing water for all is not only a question of resource availability and money, but also a matter of good governance. Water involves a wide range of stakeholders at basin, municipal, regional, national and international levels. In the absence of effective public governance to manage interdependencies across policy areas and between levels of government, policymakers inevitably face obstacles to effectively designing and implementing water reforms. In addition, good governance and financial sustainability are inextricably linked.

    pdf240p lulaula 25-10-2012 22 4   Download

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