Regulatory mechanisms

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  • Protein-tyrosine phosphatases are tightly controlled by various mecha-nisms, ranging from differential expression in specific cell types to restricted subcellular localization, limited proteolysis, post-translational modifications affecting intrinsic catalytic activity, ligand binding and dimerization. Here, we review the regulatory mechanisms found to control the classical pro-tein-tyrosine phosphatases.

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  • Over the past decades, investors, regulators, and industry self-regulatory bodies have forced banks, other financial institutions, and insurance companies to develop organizational structures and processes for the management of credit, market, and operational risk. Risk management became a hot topic for many institutions, as a means of increasing shareholder value and demonstrating the willingness and capability of top management to handle this issue.

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  • Over the past decades, investors, regulators, and industry self-regulatory bodies have forced banks, other financial institutions, and insurance companies to develop organizational structures and processes for the management of credit, market, and operational risk. Risk management became a hot topic for many institutions, as a means of increasing shareholder value and demonstrating the willingness and capability of top management to handle this issue.

    pdf578p transang4 01-10-2012 34 10   Download

  • Renewable fuels standard (RFS) policies are becoming a popular public policy mechanism for developing the market for renewable fuels in the transportation sector. During the past decade, U.S. states and several countries began implementing these more market-based (less command and control) policies to support increased biofuels production and use. This paper presents an overview of current and proposed U.S. state-level policies, as well as selected electric sector policies and international fuel standard policies. Current U.S.

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  • Note that the above assumes ultimate collection of the premium. Billed premium that is later determined to be uncollectible may be written off in several different locations, based on the particular accounting system. For example, U.S. regulatory accounting treats such uncollectible amounts as negative “other income”, while they may be accounted for as underwriting expenses under GAAP accounting. Conceivably another possibility might be negative premium. The above discussion focused on premium revenue on a calendar period basis.

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  • Within developing countries, health sector reform, often including decen- tralized priority setting, increases the information and advocacy burden for inclusion of SRH concerns. Central functions (like operating logistic systems and service quality control) require high-level commitment and a supportive policy and regulatory framework. The international discussion on SRH emphasizes an outcome-oriented public health approach but people react to multiple dimensions. Strong pas- sions and intensive debates continue on a range of issues: abortion, adolescent SRH and even family planning.

    pdf31p thankinhphanliet 21-12-2012 11 2   Download

  • The galactose uptake mechanism in yeast is a well-studied regulatory net-work. The regulatory players in the galactose regulatory mechanism (GAL system) are conserved in Saccharomyces cerevisiae and Kluyveromyces lactis, but the molecular mechanisms that occur as a result of the molecular interactions between them are different.

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  • Tham khảo sách 'risk management and capital adequacy', kinh doanh - tiếp thị, quản trị kinh doanh phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

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  • It is difficult to discern exposures from institutions’ reported credit market posi- tions. Indeed, common data sources such as annual reports and regulatory filings record accounting measures on a large and diverse number of credit market instruments. Ac- counting measures are not necessarily comparable across positions. For example, the economic value of two loans with the same book value but different maturities will react quite differently to changes in interest rates. At the same time, many instruments are close substitutes and thus entail essentially the same market risk.

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  • A truly distributed service would allow a client to use services by connecting to a broker nearest to the client’s geographical location. By having such local broker, a client does not have to re-connect all the way back to the broker that it was last attached to. If the client is not satisfied with the response times that it experiences or if the broker that it has connected to fails, the client could very well choose to connect to some other local broker.

    pdf30p nhacchovina 22-03-2013 24 7   Download

  • The dehesa is both a resilient and a fragile system; its resilience derives from the perseverance of its operators, and its fragility is its susceptibility to unfavourable economic factors that influence its profitability (Siebold, 2009). Livestock grazing is an integral management component of a dehesa and undergirds the conservation function of the system. The livestock component, including cattle, accounts for the largest fraction of revenue from the dehesa.

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  • Earlier in the year, when the affiliate rule was first implemented, the state expected that the planned expansion of Medicaid to non-elderly adults with incomes under 133% of poverty under the Affordable Care Act in 2014 would ensure that most of the low-income WHP clients would become eligible for Medicaid and that additional support might only be needed for those women with incomes between 138% and 185% of poverty.

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  • It has been a decade since book-length writing about law and the Internet began in earnest. Ethan Katsh’s wonderful book Law in a Digital World (1995) is just over a decade old, and anticipated the flood. My first book, Code and Other Laws of Cyberspace (1999), is just under. Most of these early books had a common character. We were all trying first to make the obscure understandable, and second, to draw lessons from the understood about how law and technology needed to interact.

    pdf354p bin_pham 05-02-2013 25 6   Download

  • In this paper we show that nontraded goods (in ¯nal consumption and in retail services) play an important role in exchange rate behavior in the context of an otherwise standard open-economy macro model. In our model, nontraded goods have an important role even though °uctuations in the relative price of nontraded goods account for a small proportion of real exchange rate °uctuations. 3 Our quantitative study with nontraded goods generates implications along several dimensions that are more closely in line with the data relative to the model that abstracts from nontraded goods.

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  • Tham khảo tài liệu 'market timing ability of indian mutual funds', tài chính - ngân hàng, quỹ đầu tư phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

    pdf12p hongphuocidol 04-04-2013 24 6   Download

  • Protein phosphorylation is a reversible posttranslational modification catalyzed by protein kinases and reversely by protein phosphatases. There are about 500 protein kinases and 25-30 phosphatases in human genome. Each kinase and phosphatase targets multiple substrates. Thus, protein phosphorylation is a most versatile signaling regulatory mechanism and constitutes a most complicated signaling network in living organisms. In fact, protein phosphorylation governs all aspects of physiological and pathological processes in human health....

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  • In some tropical shrimp-fishing grounds, turtles are relatively abundant and so may be captured incidentally and drown in the shrimp-trawls. Some countries have already taken action to mitigate the problem of turtle by-catch, and the use of the turtle-exclusion devices (TEDs) is for instance compulsory in tropical shrimp-fisheries in the USA as well as in other countries which wish to export shrimp to the USA but have problems with turtle by-catch. Australia has also introduced TEDs in some of its shrimp fisheries.

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  • Our first investor, the dogmatist, has extreme prior beliefs about the potential for manager skill. The dogmatist rules out any potential for skill, either fixed or time varying, for any fund manager. That is, the dogmatist’s view is that ai0 is fixed at 1 12ðexpense þ 0:01  turnoverÞ and that ai1 is fixed at zero, where expense and turnover are the fund’s reported annual expense ratio and turnover, and where we assume a round-trip total trade cost of 1% (this prior specification is similar to Pastor and Stambaugh (2002a,b)).

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  • The IDB’s measures of the impact of the funds and the outstanding is- sues and conclusions from the IDB study are summarized here. Despite the large amount of resources that the IDB and the World Bank have been lending to the funds, their scope is small. Only one fund in the region, Nicaragua, spends as much as 1 percent of the gross domes- tic product (GDP) in its fund; only three countries—Chile, Panama, and Uruguay—spend more than US$15 per year per poor person. And the poor countries on average spend less than US$10 a year.

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  • Tham khảo tài liệu 'opalesque round table series ' 13 cayman', tài chính - ngân hàng, quỹ đầu tư phục vụ nhu cầu học tập, nghiên cứu và làm việc hiệu quả

    pdf20p lenh_hoi_xung 01-03-2013 22 5   Download

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